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Tubulin beta-3 chain

Tubulin beta-3 chain, Class III β-tubulin, βIII-tubulin (β3-tubulin) or β-tubulin III, is a microtubule element of the tubulin family found almost exclusively in neurons, and in testis cells. In humans, it is encoded by the TUBB3 gene.

Function, Overview & Role in cancer

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Function

9 related topics

Overview

11 related topics

Role in cancer

1 related topics

Key facts & relationships

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Aliases
TUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta 3 class III
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ0, 5JCO, 5IJ9
Band
16q24.3 · 8|8 E1
Bgee
ganglionic eminence · superior frontal gyrus · hypothalamus · ventricular zone · primary visual cortex
BioGPS
n/a
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

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Overview

Function

Role in cancer

Advanced semantic analysis

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Map overview Semantic statistics

Tubulin beta-3 chain

Nodes25
Edges24
Triples86
Avg. degree1.92
Density0.08
Components1

How this topic connects Entity context

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Tubulin beta-3 chain

Top relations

Gene ontology · 26
Tubulin beta-3 chain → axon, axon guidance, cell projection, cytoplasm, cytoskeleton, cytoskeleton organization, dendrite, dorsal root ganglion development, extracellular exosome, filopodium, growth cone, GTP binding, GTPase activity, lamellipodium, microtubule, microtubule cytoskeleton, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, netrin receptor binding
Bgee · 17
Tubulin beta-3 chain → anterior cingulate cortex, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, ganglionic eminence, hypothalamus, medial ganglionic eminence, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, superior cervical ganglion, superior frontal gyrus, ventricular zone
RNA expression pattern · 17
Tubulin beta-3 chain → anterior cingulate cortex, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, ganglionic eminence, hypothalamus, medial ganglionic eminence, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, superior cervical ganglion, superior frontal gyrus, ventricular zone
Band · 2
Tubulin beta-3 chain → 16q24.3, 8|8 E1
Chr. · 2
Tubulin beta-3 chain → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
Tubulin beta-3 chain → 124,148,754 bp, 89,938,761 bp
Aliases · 1
Tubulin beta-3 chain → TUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta 3 class III
Available structures · 1
Tubulin beta-3 chain → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ0, 5JCO, 5IJ9
BioGPS · 1
Tubulin beta-3 chain → n/a
Databases · 1
Tubulin beta-3 chain → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

class iii β-tubulin tubb3 microtubule human gene bp cells expression cell chr band β3-tubulin chromosome neural neurons tubulin drugs βiii-tubulin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Tubulin beta-3 chainAliasesTUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta 3 class III1.00infobox
Tubulin beta-3 chainAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ0, 5JCO, 5IJ91.00infobox
Tubulin beta-3 chainBand16q24.31.00infobox
Tubulin beta-3 chainBand8|8 E11.00infobox
Tubulin beta-3 chainBgeeganglionic eminence1.00infobox
Tubulin beta-3 chainBgeesuperior frontal gyrus1.00infobox
Tubulin beta-3 chainBgeehypothalamus1.00infobox
Tubulin beta-3 chainBgeeventricular zone1.00infobox
Tubulin beta-3 chainBgeeprimary visual cortex1.00infobox
Tubulin beta-3 chainBgeeprefrontal cortex1.00infobox
Tubulin beta-3 chainBgeeright frontal lobe1.00infobox
Tubulin beta-3 chainBgeedorsolateral prefrontal cortex1.00infobox
Tubulin beta-3 chainBgeeBrodmann area 91.00infobox
Tubulin beta-3 chainBgeeanterior cingulate cortex1.00infobox
Tubulin beta-3 chainBgeesuperior cervical ganglion1.00infobox
Tubulin beta-3 chainBgeeperirhinal cortex1.00infobox
Tubulin beta-3 chainBgeemedial ganglionic eminence1.00infobox
Tubulin beta-3 chainBgeeentorhinal cortex1.00infobox
Tubulin beta-3 chainBgeefacial motor nucleus1.00infobox
Tubulin beta-3 chainBgeeCA3 field1.00infobox
Tubulin beta-3 chainBgeedentate gyrus of hippocampal formation granule cell1.00infobox
Tubulin beta-3 chainBioGPSn/a1.00infobox
Tubulin beta-3 chainChr.Chromosome 16 (human)1.00infobox
Tubulin beta-3 chainChr.Chromosome 8 (mouse)1.00infobox
Tubulin beta-3 chainDatabasesNCBI: entry; OMA: entry1.00infobox
Tubulin beta-3 chainEnd89,938,761 bp1.00infobox
Tubulin beta-3 chainEnd124,148,754 bp1.00infobox
Tubulin beta-3 chainEnsemblENSG000002589471.00infobox
Tubulin beta-3 chainEntrez103811.00infobox
Tubulin beta-3 chainExternal IDsOMIM: 602661; MGI: 107813; GeneCards: TUBB31.00infobox

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