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Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis.
Role in hematopoiesis, Production & Role in development
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scf cells c-kit hscs cell hematopoietic receptor mast also transmembrane role stem soluble bp human plays hematopoiesis expressed chr band
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Stem cell factor | Aliases | KITLG, FPH2, FPHH, KL-1, Kitl, MGF, SCF, SF, SHEP7, DCUA, KIT ligand, DFNA69, SLF | 1.00 | infobox |
| Stem cell factor | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EXZ, 1SCF, 2E9W | 1.00 | infobox |
| Stem cell factor | Band | 12q21.32 | 1.00 | infobox |
| Stem cell factor | Band | 10 D1|10 51.4 cM | 1.00 | infobox |
| Stem cell factor | Bgee | visceral pleura | 1.00 | infobox |
| Stem cell factor | Bgee | cardia | 1.00 | infobox |
| Stem cell factor | Bgee | lower lobe of lung | 1.00 | infobox |
| Stem cell factor | Bgee | pylorus | 1.00 | infobox |
| Stem cell factor | Bgee | lateral nuclear group of thalamus | 1.00 | infobox |
| Stem cell factor | Bgee | middle temporal gyrus | 1.00 | infobox |
| Stem cell factor | Bgee | parietal pleura | 1.00 | infobox |
| Stem cell factor | Bgee | endothelial cell | 1.00 | infobox |
| Stem cell factor | Bgee | skin of hip | 1.00 | infobox |
| Stem cell factor | Bgee | seminal vesicula | 1.00 | infobox |
| Stem cell factor | Bgee | habenula | 1.00 | infobox |
| Stem cell factor | Bgee | left lung lobe | 1.00 | infobox |
| Stem cell factor | Bgee | medial geniculate nucleus | 1.00 | infobox |
| Stem cell factor | Bgee | medial dorsal nucleus | 1.00 | infobox |
| Stem cell factor | Bgee | lateral geniculate nucleus | 1.00 | infobox |
| Stem cell factor | Bgee | lobe of cerebellum | 1.00 | infobox |
| Stem cell factor | Bgee | dermis | 1.00 | infobox |
| Stem cell factor | Bgee | cerebellar vermis | 1.00 | infobox |
| Stem cell factor | Bgee | cardiac muscle tissue of left ventricle | 1.00 | infobox |
| Stem cell factor | Bgee | right lung | 1.00 | infobox |
| Stem cell factor | BioGPS | More reference expression data | 1.00 | infobox |
| Stem cell factor | Chr. | Chromosome 12 (human) | 1.00 | infobox |
| Stem cell factor | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| Stem cell factor | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Stem cell factor | End | 88,580,851 bp | 1.00 | infobox |
| Stem cell factor | End | 99,936,278 bp | 1.00 | infobox |
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