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Stromal cell-derived factor 1

The stromal cell-derived factor 1 (SDF-1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of…

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Aliases
CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, C-X-C motif chemokine ligand 12
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A15, 1QG7, 1SDF, 1VMC, 2J7Z, 2K01, 2K03, 2K04, 2K05, 2KEC, 2KED, 2KEE, 2KOL, 2NWG, 2SDF, 3GV3, 3HP3, 4LMQ,…
Band
10q11.21 · 6 54.81 cM|6 F1
Bgee
synovial joint · pericardium · lactiferous duct · skin of hip · trabecular bone
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 6 (mouse)

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Stromal cell-derived factor 1

Nodes51
Edges50
Triples137
Avg. degree1.96
Density0.039216
Components1

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Stromal cell-derived factor 1

Top relations

Gene ontology · 67
Stromal cell-derived factor 1 → adult locomotory behavior, animal organ regeneration, antimicrobial humoral immune response mediated by antimicrobial peptide, axon guidance, blood circulation, brain development, cell adhesion, cell chemotaxis, cellular calcium ion homeostasis, cellular response to chemokine, chemoattractant activity, chemokine (C-X-C motif) ligand 12 signaling pathway, chemokine activity, chemokine receptor binding, chemokine-mediated signaling pathway, chemotaxis, collagen-containing extracellular matrix, CXCR chemokine receptor binding, cytokine activity, cytoplasm
Bgee · 20
Stromal cell-derived factor 1 → ankle, ankle joint, external carotid artery, gallbladder, Gonadal ridge, internal carotid artery, lactiferous duct, parietal pleura, pericardium, skin of hip, spleen, stroma of bone marrow, superficial temporal artery, synovial joint, synovial membrane, thymus, tibiofemoral joint, trabecular bone, vas deferens, vena cava
RNA expression pattern · 20
Stromal cell-derived factor 1 → ankle, ankle joint, external carotid artery, gallbladder, Gonadal ridge, internal carotid artery, lactiferous duct, parietal pleura, pericardium, skin of hip, spleen, stroma of bone marrow, superficial temporal artery, synovial joint, synovial membrane, thymus, tibiofemoral joint, trabecular bone, vas deferens, vena cava
Band · 2
Stromal cell-derived factor 1 → 10q11.21, 6 54.81 cM|6 F1
Chr. · 2
Stromal cell-derived factor 1 → Chromosome 10 (human), Chromosome 6 (mouse)
End · 2
Stromal cell-derived factor 1 → 117,158,328 bp, 44,386,493 bp
Aliases · 1
Stromal cell-derived factor 1 → CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, C-X-C motif chemokine ligand 12
Available structures · 1
Stromal cell-derived factor 1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A15, 1QG7, 1SDF, 1VMC, 2J7Z, 2K01, 2K03, 2K04, 2K05, 2KEC, 2KED, 2KEE, 2KOL, 2NWG, 2SDF, 3GV3, 3HP3, 4LMQ,…
BioGPS · 1
Stromal cell-derived factor 1 → More reference expression data
Databases · 1
Stromal cell-derived factor 1 → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

cxcl12 gene chemokine receptor cxcr4 chromosome 10 bp band also brain chr protein human chemokines alzheimer's bone cell cells motif

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Stromal cell-derived factor 1AliasesCXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, C-X-C motif chemokine ligand 121.00infobox
Stromal cell-derived factor 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A15, 1QG7, 1SDF, 1VMC, 2J7Z, 2K01, 2K03, 2K04, 2K05, 2KEC, 2KED, 2KEE, 2KOL, 2NWG, 2SDF, 3GV3, 3HP3, 4LMQ,…1.00infobox
Stromal cell-derived factor 1Band10q11.211.00infobox
Stromal cell-derived factor 1Band6 54.81 cM|6 F11.00infobox
Stromal cell-derived factor 1Bgeesynovial joint1.00infobox
Stromal cell-derived factor 1Bgeepericardium1.00infobox
Stromal cell-derived factor 1Bgeelactiferous duct1.00infobox
Stromal cell-derived factor 1Bgeeskin of hip1.00infobox
Stromal cell-derived factor 1Bgeetrabecular bone1.00infobox
Stromal cell-derived factor 1Bgeeparietal pleura1.00infobox
Stromal cell-derived factor 1Bgeesynovial membrane1.00infobox
Stromal cell-derived factor 1Bgeesuperficial temporal artery1.00infobox
Stromal cell-derived factor 1Bgeegallbladder1.00infobox
Stromal cell-derived factor 1Bgeevena cava1.00infobox
Stromal cell-derived factor 1Bgeestroma of bone marrow1.00infobox
Stromal cell-derived factor 1Bgeetibiofemoral joint1.00infobox
Stromal cell-derived factor 1BgeeGonadal ridge1.00infobox
Stromal cell-derived factor 1Bgeevas deferens1.00infobox
Stromal cell-derived factor 1Bgeeinternal carotid artery1.00infobox
Stromal cell-derived factor 1Bgeespleen1.00infobox
Stromal cell-derived factor 1Bgeeankle1.00infobox
Stromal cell-derived factor 1Bgeeankle joint1.00infobox
Stromal cell-derived factor 1Bgeeexternal carotid artery1.00infobox
Stromal cell-derived factor 1Bgeethymus1.00infobox
Stromal cell-derived factor 1BioGPSMore reference expression data1.00infobox
Stromal cell-derived factor 1Chr.Chromosome 10 (human)1.00infobox
Stromal cell-derived factor 1Chr.Chromosome 6 (mouse)1.00infobox
Stromal cell-derived factor 1DatabasesNCBI: entry; OMA: entry1.00infobox
Stromal cell-derived factor 1End44,386,493 bp1.00infobox
Stromal cell-derived factor 1End117,158,328 bp1.00infobox

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