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The stromal cell-derived factor 1 (SDF-1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of…
The analysis highlights Function, Structure and Clinical significance as prominent areas in the source structure around Stromal cell-derived factor 1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Stromal cell-derived factor 1 shows recurring relationship patterns in the source. For example, Stromal cell-derived factor 1 → adult locomotory behavior, animal organ regeneration, antimicrobial humoral immune response mediated by antimicrobial peptide, axon guidance, blood circulation, brain development, cell adhesion, cell chemotaxis, cellular calcium ion homeostasis, cellular response to chemokine, chemoattractant activity, chemokine (C-X-C motif) ligand 12 signaling pathway, chemokine activity, chemokine receptor binding, chemokine-mediated signaling pathway, chemotaxis, collagen-containing extracellular matrix, CXCR chemokine receptor binding, cytokine activity, cytoplasm Another extracted example is Stromal cell-derived factor 1 → ankle, ankle joint, external carotid artery, gallbladder, Gonadal ridge, internal carotid artery, lactiferous duct, parietal pleura, pericardium, skin of hip, spleen, stroma of bone marrow, superficial temporal artery, synovial joint, synovial membrane, thymus, tibiofemoral joint, trabecular bone, vas deferens, vena cava. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cxcl12 gene chemokine receptor cxcr4 chromosome 10 bp band also brain chr protein human chemokines alzheimer's bone cell cells motif
TTTA extracted 137 structured relationships around Stromal cell-derived factor 1. Examples in this analysis include Stromal cell-derived factor 1 → Aliases → CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, C-X-C motif chemokine ligand 12 and Stromal cell-derived factor 1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A15, 1QG7, 1SDF, 1VMC, 2J7Z, 2K01, 2K03, 2K04, 2K05, 2KEC, 2KED, 2KEE, 2KOL, 2NWG, 2SDF, 3GV3, 3HP3, 4LMQ,…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Stromal cell-derived factor 1 | Aliases | CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, C-X-C motif chemokine ligand 12 | 1.00 | infobox |
| Stromal cell-derived factor 1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A15, 1QG7, 1SDF, 1VMC, 2J7Z, 2K01, 2K03, 2K04, 2K05, 2KEC, 2KED, 2KEE, 2KOL, 2NWG, 2SDF, 3GV3, 3HP3, 4LMQ,… | 1.00 | infobox |
| Stromal cell-derived factor 1 | Band | 10q11.21 | 1.00 | infobox |
| Stromal cell-derived factor 1 | Band | 6 54.81 cM|6 F1 | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | synovial joint | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | pericardium | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | lactiferous duct | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | skin of hip | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | trabecular bone | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | parietal pleura | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | synovial membrane | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | superficial temporal artery | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | gallbladder | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | vena cava | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | stroma of bone marrow | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | tibiofemoral joint | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | Gonadal ridge | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | vas deferens | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | internal carotid artery | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | spleen | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | ankle | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | ankle joint | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | external carotid artery | 1.00 | infobox |
| Stromal cell-derived factor 1 | Bgee | thymus | 1.00 | infobox |
| Stromal cell-derived factor 1 | BioGPS | More reference expression data | 1.00 | infobox |
| Stromal cell-derived factor 1 | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| Stromal cell-derived factor 1 | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| Stromal cell-derived factor 1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Stromal cell-derived factor 1 | End | 44,386,493 bp | 1.00 | infobox |
| Stromal cell-derived factor 1 | End | 117,158,328 bp | 1.00 | infobox |
The concept neighborhoods around Stromal cell-derived factor 1 bring nearby vocabulary together. In this analysis, examples include Motif, Chromosome and Expression. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Stromal cell-derived factor 1, one of the stronger structural bridges in this analysis connects Stromal cell-derived factor 1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Stromal cell-derived factor 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Structure & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Stromal cell-derived factor 1 · EN edition · Analysis: TopicsToTalkAbout