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Superoxide dismutase also known as superoxide dismutase 1 or hSod1 is an enzyme that in humans is encoded by the SOD1 gene, located on chromosome 21. SOD1 is one of three human superoxide dismutases. It is implicated in apoptosis, familial amyotrophic lateral sclerosis and Parkinson's disease.
The analysis highlights Clinical significance, Structure and Function as prominent areas in the source structure around SOD1. 1 topic appears in more than one source area, which can help identify connections that are less obvious in a linear reading.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around SOD1 shows recurring relationship patterns in the source. For example, SOD1 → ageing, anterograde axonal transport, antioxidant activity, auditory receptor cell stereocilium organization, axon cytoplasm, cellular iron ion homeostasis, cellular response to ATP, cellular response to cadmium ion, cellular response to oxidative stress, cellular response to potassium ion, chaperone binding, copper ion binding, cytoplasm, cytoplasmic vesicle, cytosol, dendrite cytoplasm, dense core granule, embryo implantation, enzyme binding, extracellular exosome Another extracted example is SOD1 → Brodmann area 10, condyle, cumulus cell, Epithelium of choroid plexus, facial motor nucleus, fossa, hypothalamus, lateral nuclear group of thalamus, otolith organ, Paneth cell, pars compacta, pars reticulata, pons, primary oocyte, right adrenal cortex, right lobe of liver, spinal ganglia, superior vestibular nucleus, utricle, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
als g93a gene a4v superoxide disease mutation human chromosome 21 mitochondrial oxidative bp mouse enzyme h46r mutations one chr band
TTTA extracted 217 structured relationships around SOD1. Examples in this analysis include SOD1 → 1.15.1.1 → ↗ and SOD1 → Aliases → SOD1, ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodimer, superoxide dismutase 1, soluble, superoxide dismutase 1, STAHP. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SOD1 | 1.15.1.1 | ↗ | 1.00 | infobox |
| SOD1 | Aliases | SOD1, ALS, ALS1, HEL-S-44, IPOA, SOD, hSod1, homodimer, superoxide dismutase 1, soluble, superoxide dismutase 1, STAHP | 1.00 | infobox |
| SOD1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AZV, 1BA9, 1DSW, 1FUN, 1HL4, 1HL5, 1KMG, 1L3N, 1MFM, 1N18, 1N19, 1OEZ, 1OZT, 1OZU, 1P1V, 1PTZ, 1PU0, 1RK7,… | 1.00 | infobox |
| SOD1 | Band | 21q22.11 | 1.00 | infobox |
| SOD1 | Band | 16 C3.3|16 51.56 cM | 1.00 | infobox |
| SOD1 | Bgee | pons | 1.00 | infobox |
| SOD1 | Bgee | pars compacta | 1.00 | infobox |
| SOD1 | Bgee | spinal ganglia | 1.00 | infobox |
| SOD1 | Bgee | lateral nuclear group of thalamus | 1.00 | infobox |
| SOD1 | Bgee | superior vestibular nucleus | 1.00 | infobox |
| SOD1 | Bgee | pars reticulata | 1.00 | infobox |
| SOD1 | Bgee | right lobe of liver | 1.00 | infobox |
| SOD1 | Bgee | Brodmann area 10 | 1.00 | infobox |
| SOD1 | Bgee | right adrenal cortex | 1.00 | infobox |
| SOD1 | Bgee | hypothalamus | 1.00 | infobox |
| SOD1 | Bgee | otolith organ | 1.00 | infobox |
| SOD1 | Bgee | utricle | 1.00 | infobox |
| SOD1 | Bgee | Paneth cell | 1.00 | infobox |
| SOD1 | Bgee | cumulus cell | 1.00 | infobox |
| SOD1 | Bgee | fossa | 1.00 | infobox |
| SOD1 | Bgee | primary oocyte | 1.00 | infobox |
| SOD1 | Bgee | vestibular sensory epithelium | 1.00 | infobox |
| SOD1 | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| SOD1 | Bgee | facial motor nucleus | 1.00 | infobox |
| SOD1 | Bgee | condyle | 1.00 | infobox |
| SOD1 | BioGPS | More reference expression data | 1.00 | infobox |
| SOD1 | Chr. | Chromosome 21 (human) | 1.00 | infobox |
| SOD1 | Chr. | Chromosome 16 (mouse) | 1.00 | infobox |
| SOD1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| SOD1 | End | 31,668,931 bp | 1.00 | infobox |
The concept neighborhoods around SOD1 bring nearby vocabulary together. In this analysis, examples include Gene, Als and Superoxide. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SOD1, one of the stronger structural bridges in this analysis connects SOD1 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SOD1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SOD1 · EN edition · Analysis: TopicsToTalkAbout