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Ischemic preconditioning

Ischemic preconditioning (IPC) is a technique for producing resistance to the loss of blood supply, and thus oxygen, to tissues of many types. In the heart, IPC is an intrinsic process whereby repeated short episodes of ischaemia protect the myocardium against a subsequent ischaemic insult and reperfusion injury.

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MeSH
D019194

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Ischemic preconditioning

Nodes43
Edges42
Triples11
Avg. degree1.95
Density0.046512
Components1

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Ischemic preconditioning

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MeSH · 1
Ischemic preconditioning → D019194

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Important terminology

ischemic ipc preconditioning coronary reperfusion heart citation needed population artery conditioning phenomenon blood methadone less downstream patients general injury ischaemic

Entity relationships Subject–Predicate–Object triples

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SubjectPredicateObjectConfidenceSrc
Ischemic preconditioningMeSHD0191941.00infobox
the delta active opiatesinstance ofMechanismsInvestigations of various exogenous circulating ligands0.80text
opioids simulate the phenomenon of IPC thus protecting the downstream tissues without the IPC intermittent ligating procedure.Early preconditioningEarly preconditioning is thought to be stimulated by local action of adenosineinstance ofMechanismsInvestigations of various exogenous circulating ligands0.80text
opiatesinstance ofMechanismsInvestigations of various exogenous circulating ligands0.80text
and bradykinininstance ofMechanismsInvestigations of various exogenous circulating ligands0.80text
which are all endogenously released by ischemic cellsinstance ofMechanismsInvestigations of various exogenous circulating ligands0.80text
hypercholesterolemiainstance ofImpairment of preconditioningIt has also been shown that the protective effect of IPC is suppressed by pathological conditions0.80text
hyperglycemiainstance ofImpairment of preconditioningIt has also been shown that the protective effect of IPC is suppressed by pathological conditions0.80text
hypertensioninstance ofImpairment of preconditioningIt has also been shown that the protective effect of IPC is suppressed by pathological conditions0.80text
cardiac hypertrophyinstance ofImpairment of preconditioningIt has also been shown that the protective effect of IPC is suppressed by pathological conditions0.80text
and hyperhomocysteinemiainstance ofImpairment of preconditioningIt has also been shown that the protective effect of IPC is suppressed by pathological conditions0.80text

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