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Roxithromycin

Roxithromycin is a semi-synthetic macrolide antibiotic used to treat respiratory tract, urinary and soft tissue infections. It is a derivative of erythromycin - comprising the same 14-membered lactone ring - with an oxime-based side chain attached to the macrolide ring.

History, Drug interactions & Mechanism of action

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Drug interactions

Cytochrome P450Hormonal contraceptivesPrednisoloneCarbamazepineRanitidine
10 related topics

History

Roussel Uclaf
1 related topics

Mechanism of action

BacteriaProtein synthesisRibosomePeptidesLegionella pneumophila
5 related topics

Pharmacokinetics

PhagocytesPhagocytes
2 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
J01FA06 (WHO)
CAS Number
80214-83-1 Y
ChEBI
CHEBI:48935 Y
ChEMBL
ChEMBL1214185 Y

Topics to explore

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Overview

Side effects

Drug interactions

Mechanism of action

Pharmacokinetics

History

Advanced semantic analysis

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Map overview Semantic statistics

Roxithromycin

Nodes31
Edges30
Triples43
Avg. degree1.94
Density0.064516
Components1

How this topic connects Entity context

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Roxithromycin

Top relations

related to External links · 5
Roxithromycin → Archived, Drug Information Portal, July, Medicine, National Library
related to Metabolism · 4
Roxithromycin → Most, Only, Roxithromycin's, Under
related to Pharmacokinetics · 3
Roxithromycin → Due, During, When
Legal status · 2
Roxithromycin → AU: S4 (Prescription only), In general: ℞ (Prescription only)
related to history · 2
Roxithromycin → French, Roussel Uclaf
3D model (JSmol) · 1
Roxithromycin → Interactive image
AHFS/Drugs.com · 1
Roxithromycin → International Drug Names
ATC code · 1
Roxithromycin → J01FA06 (WHO)
CAS Number · 1
Roxithromycin → 80214-83-1 Y
ChEBI · 1
Roxithromycin → CHEBI:48935 Y

Important terminology Word statistics

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Important terminology

side citation needed erythromycin effects available macrolide drug shown hours concentration names metabolism 1987 interactions theophylline plasma warfarin bacteria phagocytes

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Roxithromycin3D model (JSmol)Interactive image1.00infobox
RoxithromycinAHFS/Drugs.comInternational Drug Names1.00infobox
RoxithromycinATC codeJ01FA06 (WHO)1.00infobox
RoxithromycinCAS Number80214-83-1 Y1.00infobox
RoxithromycinChEBICHEBI:48935 Y1.00infobox
RoxithromycinChEMBLChEMBL1214185 Y1.00infobox
RoxithromycinChemSpider5291557 Y1.00infobox
RoxithromycinCompTox Dashboard (EPA)DTXSID80411171.00infobox
RoxithromycinDrugBankDB00778 Y1.00infobox
RoxithromycinECHA InfoCard100.121.3081.00infobox
RoxithromycinElimination half-life11 hours1.00infobox
RoxithromycinFormulaC41H76N2O151.00infobox
RoxithromycinIUPHAR/BPS14651.00infobox
RoxithromycinKEGGD01710 Y1.00infobox
RoxithromycinLegal statusAU: S4 (Prescription only)1.00infobox
RoxithromycinLegal statusIn general: ℞ (Prescription only)1.00infobox
RoxithromycinMetabolismLiver, peak concentration averaging 2 hours after ingestion.1.00infobox
RoxithromycinMolar mass837.058 g·mol−11.00infobox
RoxithromycinPDB ligandROX (PDBe, RCSB PDB)1.00infobox
RoxithromycinPregnancy categoryAU: B11.00infobox
RoxithromycinPubChem CID69157441.00infobox
RoxithromycinTrade namesRulide, Biaxsig, others1.00infobox
RoxithromycinUNII21KOF230FA1.00infobox
Roxithromycinis asemi-synthetic macrolide antibiotic used to treat respiratory tract0.90text

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