Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Roxithromycin: History, Drug interactions & Mechanism of action

Roxithromycin is a semi-synthetic macrolide antibiotic used to treat respiratory tract, urinary and soft tissue infections. It is a derivative of erythromycin - comprising the same 14-membered lactone ring - with an oxime-based side chain attached to the macrolide ring.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Roxithromycin topic overview

The analysis highlights History, Drug interactions and Mechanism of action as prominent areas in the source structure around Roxithromycin.

Related topics
24
Source areas
6
Connected nodes
30
Extracted relationships
43
Concept neighborhoods
14
Bridge connections
30

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Drug interactions · 10 topics
Mechanism of action · 5 topics
Overview · 5 topics
Pharmacokinetics · 2 topics
History · 1 topics
Side effects · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
J01FA06 (WHO)
CAS Number
80214-83-1 Y
ChEBI
CHEBI:48935 Y
ChEMBL
ChEMBL1214185 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Side effects

Drug interactions

Mechanism of action

Pharmacokinetics

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Roxithromycin connects Entity context

The extracted context around Roxithromycin shows recurring relationship patterns in the source. For example, Roxithromycin → Archived, Drug Information Portal, July, Medicine, National Library Another extracted example is Roxithromycin → Most, Only, Roxithromycin's, Under. Use these groups to spot repeated connection types before inspecting the individual relationships.

Roxithromycin

Top relations

related to External links · 5
Roxithromycin → Archived, Drug Information Portal, July, Medicine, National Library
related to Metabolism · 4
Roxithromycin → Most, Only, Roxithromycin's, Under
related to Pharmacokinetics · 3
Roxithromycin → Due, During, When
Legal status · 2
Roxithromycin → AU: S4 (Prescription only), In general: ℞ (Prescription only)
related to history · 2
Roxithromycin → French, Roussel Uclaf
3D model (JSmol) · 1
Roxithromycin → Interactive image
AHFS/Drugs.com · 1
Roxithromycin → International Drug Names
ATC code · 1
Roxithromycin → J01FA06 (WHO)
CAS Number · 1
Roxithromycin → 80214-83-1 Y
ChEBI · 1
Roxithromycin → CHEBI:48935 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

side citation needed erythromycin effects available macrolide drug shown hours concentration names metabolism 1987 interactions theophylline plasma warfarin bacteria phagocytes

Roxithromycin relationships Subject–Predicate–Object triples

TTTA extracted 43 structured relationships around Roxithromycin. Examples in this analysis include Roxithromycin → 3D model (JSmol) → Interactive image and Roxithromycin → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Roxithromycin3D model (JSmol)Interactive image1.00infobox
RoxithromycinAHFS/Drugs.comInternational Drug Names1.00infobox
RoxithromycinATC codeJ01FA06 (WHO)1.00infobox
RoxithromycinCAS Number80214-83-1 Y1.00infobox
RoxithromycinChEBICHEBI:48935 Y1.00infobox
RoxithromycinChEMBLChEMBL1214185 Y1.00infobox
RoxithromycinChemSpider5291557 Y1.00infobox
RoxithromycinCompTox Dashboard (EPA)DTXSID80411171.00infobox
RoxithromycinDrugBankDB00778 Y1.00infobox
RoxithromycinECHA InfoCard100.121.3081.00infobox
RoxithromycinElimination half-life11 hours1.00infobox
RoxithromycinFormulaC41H76N2O151.00infobox
RoxithromycinIUPHAR/BPS14651.00infobox
RoxithromycinKEGGD01710 Y1.00infobox
RoxithromycinLegal statusAU: S4 (Prescription only)1.00infobox
RoxithromycinLegal statusIn general: ℞ (Prescription only)1.00infobox
RoxithromycinMetabolismLiver, peak concentration averaging 2 hours after ingestion.1.00infobox
RoxithromycinMolar mass837.058 g·mol−11.00infobox
RoxithromycinPDB ligandROX (PDBe, RCSB PDB)1.00infobox
RoxithromycinPregnancy categoryAU: B11.00infobox
RoxithromycinPubChem CID69157441.00infobox
RoxithromycinTrade namesRulide, Biaxsig, others1.00infobox
RoxithromycinUNII21KOF230FA1.00infobox
Roxithromycinis asemi-synthetic macrolide antibiotic used to treat respiratory tract0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Roxithromycin bring nearby vocabulary together. In this analysis, examples include Citation, Needed and Concentration. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Roxithromycin
    • Citation
    • Needed
    • Concentration
    • Shown
    • Bacteria
    • Increase
    • Interact
    • Interactions
    • International
    • Liver
    • Phagocytes
    • Synthesis
  • roxithromycin
    • Citation
    • Needed
    • Concentration
    • Shown
    • Bacteria
    • Increase
    • Interact
    • Interactions
    • International
    • Liver
    • Phagocytes
    • Synthesis
  • side effects
    • Effects
    • Side
    • Common
    • Interactions
    • Liver
    • Hours
    • Erythromycin
    • Needed
    • Citation
    • Metabolism
    • Drug
    • Half-life
  • side chain
    • Effects
    • Common
    • Interactions
    • Liver
    • Erythromycin
    • Hours
    • Citation
    • Needed
    • Metabolism
    • Drug
    • Half-life
    • International
  • drug interactions
    • Liver
    • Metabolism
    • Needed
    • Side
    • Interactions
    • International
    • Names
    • Concentration
    • Hours
    • Shown
    • Effects
    • Roxithromycin
  • macrolide
    • Antibiotic
    • Respiratory
    • Semi-synthetic
    • Tract
    • Treat
    • Urinary
    • Used
    • Erythromycin
    • Side
    • Roxithromycin
  • erythromycin
    • Citation
    • Needed
    • Side
    • Bacteria
    • Interactions
    • Liver
    • Macrolide
    • Phagocytes
    • Effects
    • Roxithromycin
  • antibiotic
    • Respiratory
    • Semi-synthetic
    • Tract
    • Treat
    • Urinary
    • Used
    • Macrolide
    • Roxithromycin

Connections between topic areas Semantic bridges

For Roxithromycin, one of the stronger structural bridges in this analysis connects Roxithromycin with Drug interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Roxithromycin — Drug interactions · splits 20 ⟂ 11
Roxithromycin — Overview · splits 25 ⟂ 6
Roxithromycin — Mechanism of action · splits 25 ⟂ 6
Roxithromycin — Pharmacokinetics · splits 28 ⟂ 3

Map overview Semantic statistics

Roxithromycin

Nodes31
Edges30
Triples43
Avg. degree1.94
Density0.064516
Components1

Source & methodology

TTTA analyzes the structure around Roxithromycin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Drug interactions & Mechanism of action, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Roxithromycin · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.