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Ribonuclease

Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7 (for the phosphorolytic enzymes) and 3.1 (for the hydrolytic enzymes) classes of enzymes.

Classification, Function & RNase contamination during RNA extraction

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Classification

RNase APDBDenaturedRNase HRNase III
31 related topics

Function

RNase ACodingNoncoding RNARNA interferenceReplication
19 related topics

RNase contamination during RNA extraction

Extraction of RNADNasesExapted
3 related topics

RNase specificity

CRISPR
1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR000026 · PF00545
Available protein structures:
IPR000026 · PF00545
InterPro
IPR000026
PDB
1mgwA:56-137 1mgrA:56-137 1uckB:11-92 1i70A:11-92 2sarA:11-92 1ucjB:11-92 1lniB:11-92 1ay7A:11-92 1t2hB:11-92 1boxA:11-92 1uclA:11-92 1rgeB:11-92 1t2iA:11-92 1c54A:11-92 1rsnB:1…
Pfam
PF00545
SCOP2
1brn / SCOPe / SUPFAM

Topics to explore

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Overview

Function

Classification

RNase specificity

RNase contamination during RNA extraction

Advanced semantic analysis

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Map overview Semantic statistics

Ribonuclease

Nodes66
Edges65
Triples82
Avg. degree1.97
Density0.030303
Components1

How this topic connects Entity context

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Ribonuclease

Top relations

related to Major types of endoribonucleases · 21
Ribonuclease → As, Dicer, DNA, DNA/RNA, EC, EC3, EC4, In, It, One, PDB, RecA/LexA, RNA, RNAs, RNase, RNase III, RNase PhyM, RNase T1, RNase T2, RNase U2
related to Major types of exoribonucleases · 13
Ribonuclease → EC, EC2, EC3, Exoribonuclease, Exoribonuclease II, Oligoribonuclease, PNPase, Polynucleotide Phosphorylase, RNA, RNAs, RNase, RNase II, RNase PH
related to Sources · 13
Ribonuclease → Academic Press, Christensen SK, D'Alessio, Functions, Gerdes, Lobner-Olesen, Microbiol, Nat, Prokaryotic, Rev, Ribonucleases, Riordan JF, Structures
related to Function · 11
Ribonuclease → All, EndoU-like RNases, Ribonucleases, RNA, RNAs, RNase, RNases, RNP, Some, T1, While
related to RNase contamination during RNA extraction · 8
Ribonuclease → Certain RNases, DNases, For, In, RNA, RNase, RNases, The
related to RNase specificity · 5
Ribonuclease → Although, CRISPR/Cas, DNA, It, The
AlphaFold · 2
Ribonuclease → IPR000026, PF00545
Available protein structures: · 2
Ribonuclease → IPR000026, PF00545
InterPro · 1
Ribonuclease → IPR000026
PDB · 1
Ribonuclease → 1mgwA:56-137 1mgrA:56-137 1uckB:11-92 1i70A:11-92 2sarA:11-92 1ucjB:11-92 1lniB:11-92 1ay7A:11-92 1t2hB:11-92 1boxA:11-92 1uclA:11-92 1rgeB:11-92 1t2iA:11-92 1c54A:11-92 1rsnB:1…

Important terminology Word statistics

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Important terminology

rnase rna ec rnases ec3 specific number rnas single-stranded cleaves residues endoribonucleases sequence ribonucleases dna also activity 3'-end 26 functions

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RibonucleaseAlphaFoldIPR0000261.00infobox
RibonucleaseAlphaFoldPF005451.00infobox
RibonucleaseAvailable protein structures:IPR0000261.00infobox
RibonucleaseAvailable protein structures:PF005451.00infobox
RibonucleaseInterProIPR0000261.00infobox
RibonucleasePDB1mgwA:56-137 1mgrA:56-137 1uckB:11-92 1i70A:11-92 2sarA:11-92 1ucjB:11-92 1lniB:11-92 1ay7A:11-92 1t2hB:11-92 1boxA:11-92 1uclA:11-92 1rgeB:11-92 1t2iA:11-92 1c54A:11-92 1rsnB:1…1.00infobox
RibonucleasePfamPF005451.00infobox
RibonucleaseSCOP21brn / SCOPe / SUPFAM1.00infobox
RibonucleaseSymbolRibonuclease1.00infobox
Ainstance ofRNA interference and replication in retroviruses.Some cells also secrete copious quantities of non-specific RNases0.80text
T1instance ofRNA interference and replication in retroviruses.Some cells also secrete copious quantities of non-specific RNases0.80text
Ribonucleaserelated to FunctionRibonucleases0.60section

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