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Deoxyribonuclease

Deoxyribonuclease (DNase, for short) refers to a group of glycoprotein endonucleases which are enzymes that catalyze the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA. The role of the DNase enzyme in cells includes breaking down extracellular DNA (eDNA) excreted by apoptosis, necrosis, and neutrophil extracellular…

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Deoxyribonuclease

Nodes93
Edges92
Triples35
Avg. degree1.98
Density0.021505
Components1

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Deoxyribonuclease

Top relations

related to External links · 9
Deoxyribonuclease → Deoxyribonucleases, DNases, InterPro Website, Medicine Medical Subject Headings, MeSH, Sigma-Aldrich Solutions, Thermo Fisher Scientific Inc, US National Library, WebsiteDeoxyribonuclease
related to Mechanism · 8
Deoxyribonuclease → DNA, DNase, Other DNases, Others, Some DNases, The, This, UV
related to Types · 5
Deoxyribonuclease → DNase, DNase II, II, The, These
see also · 5
Deoxyribonuclease → Deoxyribonuclease II, DNase, DNase II, EndonucleaseEnzymeHydrolysisPhosphodiester, Extracellular DNA
related to Mechanism of DNase II · 4
Deoxyribonuclease → Deoxyribonuclease II, DNase II, Some, Unlike DNase

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Important terminology

dnase dna ii enzyme two treatment edna structure phosphodiester blood dnases known high activity studies inflammatory ph absorbance enzymes found

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
asthmainstance ofis used as a treatment to increase pulmonary function.Other respiratory illness0.80text
pleural empyemainstance ofis used as a treatment to increase pulmonary function.Other respiratory illness0.80text
and chronic obstructive pulmonary disease have also been found to be positively affected by DNases properties.Furthermoreinstance ofis used as a treatment to increase pulmonary function.Other respiratory illness0.80text
recent studies show that intrapleural tissue plasminogen activatorinstance ofis used as a treatment to increase pulmonary function.Other respiratory illness0.80text
Deoxyribonucleaserelated to External linksDeoxyribonucleases0.60section
Deoxyribonucleaserelated to External linksUS National Library0.60section
Deoxyribonucleaserelated to External linksMedicine Medical Subject Headings0.60section
Deoxyribonucleaserelated to External linksMeSH0.60section
Deoxyribonucleaserelated to External linksDNases0.60section
Deoxyribonucleaserelated to External linksThermo Fisher Scientific Inc0.60section
Deoxyribonucleaserelated to External linksWebsiteDeoxyribonuclease0.60section
Deoxyribonucleaserelated to External linksSigma-Aldrich Solutions0.60section

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