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Retinol: History, Measurement & Applications

Retinol is a hydrolytic metabolite of retinyl esters belonging to the group of vitamin A1 as an alcohol form. Retinol or other forms of vitamin A are fat-soluble vitamins that are found in food and used as a dietary supplement. Either of them is needed for vision, cellular development, maintenance of skin and mucous membranes, immune function and…

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Retinol topic overview

The analysis highlights History, Measurement and Applications as prominent areas in the source structure around Retinol.

Related topics
127
Source areas
9
Connected nodes
136
Extracted relationships
133
Concept neighborhoods
28
Bridge connections
136

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Biological roles · 43 topics
Overview · 19 topics
History · 16 topics
Synthesis · 15 topics
Nutrition · 13 topics
Side effects · 10 topics
Chemistry · 7 topics
Medical uses · 2 topics
Units of measurement · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A11CA01 (WHO) D10AD02 (WHO), R01AX02 (WHO), S01XA02 (WHO)
Boiling point
137–138 °C (279–280 °F) (10−6 mm Hg)
CAS Number
68-26-8 · mixture: 11103-57-4
ChEBI
CHEBI:17336

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Biological roles

Units of measurement

Nutrition

Chemistry

Synthesis

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Retinol connects Entity context

The extracted context around Retinol shows recurring relationship patterns in the source. For example, Retinol → David Adriaan, Dorp, Dutch, Elmer McCollum, Frederick Gowland Hopkins, George Wald, Hopkins, In, Jozef Ferdinand Arens, Lafayette Mendel, Madison, Marguerite Davis, Medicine, Nobel Prize, One, Paul Karrer, Photoreceptor, Physiology, Retinoic, Swiss Another extracted example is Retinol → BASF, Before, DSM, Each, European Commission, Euros, Grignard, Hoffman-La Roche, Hoffmann-La Roche, In, Ionone, Pure, Rhone-Poulenc, Roche, The, When. Use these groups to spot repeated connection types before inspecting the individual relationships.

Retinol

Top relations

related to history · 27
Retinol → David Adriaan, Dorp, Dutch, Elmer McCollum, Frederick Gowland Hopkins, George Wald, Hopkins, In, Jozef Ferdinand Arens, Lafayette Mendel, Madison, Marguerite Davis, Medicine, Nobel Prize, One, Paul Karrer, Photoreceptor, Physiology, Retinoic, Swiss
related to Industrial synthesis · 16
Retinol → BASF, Before, DSM, Each, European Commission, Euros, Grignard, Hoffman-La Roche, Hoffmann-La Roche, In, Ionone, Pure, Rhone-Poulenc, Roche, The, When
related to Skin · 11
Retinol → AMPs, Another, As, Clinical, Deficiencies, Keratinocytes, Production, RA, The, Vitamin, When
has effect · 10
Retinol → During, In, International Units, IU, RAE, RAE/day, RDA, Retinol Activity Units, The IU, The Recommended Daily Intake
related to Nutrition · 10
Retinol → For, International Units, One RE, RE, Retinol Equivalents, Retinyl, There, These, This, While Vitamin
related to Dietary intake · 8
Retinol → DRI, During, IU, Liver, National Health Service, RDA, Recommended Daily Amount, The Dietary Reference Intake
related to Vision · 7
Retinol → In, Night, RPE65, The, This, When, Without
related to Chemistry · 6
Retinol → For, Many, Nevertheless, Rhodopsin, Schiff, The
related to Biosynthesis · 5
Retinol → First, NADH, Retinal, The, This
CAS Number · 2
Retinol → 68-26-8, mixture: 11103-57-4

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

vitamin retinoic acid deficiency skin cells dietary iu used liver 000 retinal vision opsin development may doses cell food needed

Retinol relationships Subject–Predicate–Object triples

TTTA extracted 133 structured relationships around Retinol. Examples in this analysis include Retinol → 3D model (JSmol) → Interactive image and Retinol → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Retinol3D model (JSmol)Interactive image1.00infobox
RetinolAHFS/Drugs.comMonograph1.00infobox
RetinolATC codeA11CA01 (WHO) D10AD02 (WHO), R01AX02 (WHO), S01XA02 (WHO)1.00infobox
RetinolBoiling point137–138 °C (279–280 °F) (10−6 mm Hg)1.00infobox
RetinolCAS Number68-26-81.00infobox
RetinolCAS Numbermixture: 11103-57-41.00infobox
RetinolChEBICHEBI:173361.00infobox
RetinolChEMBLChEMBL9861.00infobox
RetinolChemSpider3930121.00infobox
RetinolCompTox Dashboard (EPA)DTXSID30235561.00infobox
RetinolDrug classvitamin1.00infobox
RetinolDrugBankDB001621.00infobox
RetinolECHA InfoCard100.000.6211.00infobox
RetinolFormulaC20H30O1.00infobox
RetinolIUPHAR/BPS40531.00infobox
RetinolKEGGD000691.00infobox
RetinolLegal statusUS: OTC1.00infobox
RetinolLicense dataUS DailyMed: Retinol1.00infobox
RetinolMelting point62–64 °C (144–147 °F)1.00infobox
RetinolMolar mass286.459 g·mol−11.00infobox
RetinolPDB ligandRTL (PDBe, RCSB PDB)1.00infobox
RetinolPubChem CID4453541.00infobox
RetinolRoutes of administrationBy mouth, intramuscular1.00infobox
RetinolSolubility in water0.000017 mg/mL (20 °C)1.00infobox
RetinolUNIIG2SH0XKK911.00infobox
RetinolUNIImixture: 81G40H8B0T1.00infobox
Retinolis ahydrolytic metabolite of retinyl esters belonging to the group of vitamin A1 as an alcohol form0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Retinol bring nearby vocabulary together. In this analysis, examples include Retinal, Vitamin and Dietary. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Retinol
    • Retinal
    • Vitamin
    • Dietary
    • Ester
    • Acid
    • Retinoic
    • Used
    • Iu
    • First
    • Forms
    • Body
    • Food
  • retinol
    • Retinal
    • Vitamin
    • Dietary
    • Ester
    • Acid
    • Retinoic
    • Used
    • Iu
    • First
    • Forms
    • Body
    • Food
  • vitamin a deficiency
    • Deficiency
    • Vitamin
    • Iu
    • Used
    • Retinol
    • Rhodopsin
    • High
    • May
    • Needed
    • Cell
    • Dietary
    • Cells
  • vitamin a
    • Deficiency
    • Iu
    • Retinol
    • Needed
    • Dietary
    • Cells
    • Food
    • Development
    • Used
    • Skin
    • Form
    • Sources
  • retinol binding protein
    • Opsin
    • 11-cis-retinal
    • Retinal
    • Vitamin
    • Dietary
    • Ester
    • Acid
    • Retinoic
    • Rhodopsin
    • Used
    • Via
    • Iu
  • retinol dehydrogenase
    • Retinal
    • Vitamin
    • Dietary
    • Ester
    • Acid
    • Retinoic
    • Used
    • Iu
    • First
    • Forms
    • Body
    • Food
  • embryonic stem cells
    • Differentiation
    • Protein
    • Liver
    • Immune
    • Needed
    • Opsin
    • Retinoic
    • Used
    • Vitamin
    • Skin
    • Deficiency
    • Ester
  • photoreceptor cells
    • Differentiation
    • Protein
    • Liver
    • Immune
    • Needed
    • Opsin
    • Retinoic
    • Used
    • Vitamin
    • Skin
    • Deficiency
    • Ester

Connections between topic areas Semantic bridges

For Retinol, one of the stronger structural bridges in this analysis connects Retinol with Biological roles. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Retinol — Biological roles · splits 93 ⟂ 44
Retinol — Overview · splits 117 ⟂ 20
Retinol — History · splits 120 ⟂ 17
Retinol — Synthesis · splits 121 ⟂ 16
Retinol — Nutrition · splits 123 ⟂ 14
Retinol — Side effects · splits 126 ⟂ 11
Retinol — Chemistry · splits 129 ⟂ 8
Retinol — Medical uses · splits 134 ⟂ 3
Retinol — Units of measurement · splits 134 ⟂ 3

Map overview Semantic statistics

Retinol

Nodes137
Edges136
Triples133
Avg. degree1.99
Density0.014599
Components1

Source & methodology

TTTA analyzes the structure around Retinol to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Measurement & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Retinol · EN edition · Analysis: TopicsToTalkAbout

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