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Origin of replication

The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. Propagation of the genetic material between generations requires timely and accurate duplication of DNA by semiconservative replication prior to cell division to ensure each daughter cell receives the full complement of…

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Eukaryotic

Bacterial Genome sizes Protein complex G1 S phase

19 related topics

Features

Cell cycle Polyploidy Aneuploidy Transcription DNA repair

10 related topics

Replicon model

Jacob Brenner Helicases Plasmid Prokaryotes

7 related topics

Bacterial

DNA unwinding element Helix-turn-helix ATPase AAA+ATP

6 related topics

Topics to explore

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Overview

Features

Replicon model

Jacob François Jacob
Brenner Sydney Brenner
Helicases Helicase
Plasmid
Prokaryotes Prokaryote
Eukaryotes Eukaryote
Chromatin

Bacterial

DNA unwinding element
Helix-turn-helix
ATPase
AAA+ AAA proteins
ATP Adenosine triphosphate
Protomers Promoter (genetics)

Archaeal

Eukaryotic

Bacterial Bacteria
Genome sizes Genome size
Protein complex
G1 G1 phase
S phase
Consensus sequence
Origin recognition complex
Nucleosome
Epigenetic Epigenetics
Orc4
Orc6
Orc1
H4K20 methylation H4K20me
Cdc6
Cdt1 DNA replication factor CDT1
Minichromosome maintenance 2-7 Minichromosome maintenance
Cyclin-dependent kinase
Heterochromatic Heterochromatin
Chromatin-modifying enzymes Chromatin remodeling

Viral

Polyoma
DNA polymerases DNA polymerase
T antigen SV40 Large T-antigen

Variations

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Map overview Semantic statistics

Origin of replication

Nodes66

Edges65

Triples15

Avg. degree1.97

Density0.030303

Components1

How this topic connects Entity context

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Origin of replication

Top relations

related to Viral · 4

Origin of replication → DNA, For, Polyoma, Viruses

Important terminology Word statistics

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Important terminology

dna replication origins origin initiation initiator elements bacterial orc1 cdc6 binding eukaryotic archaeal also sequence cells regions dnaa sites events

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
prokaryotes	instance of	This can either involve the replication of DNA in living organisms	0.80	text
eukaryotes	instance of	This can either involve the replication of DNA in living organisms	0.80	text
or that of DNA or RNA in viruses	instance of	This can either involve the replication of DNA in living organisms	0.80	text
such as double-stranded RNA viruses	instance of	This can either involve the replication of DNA in living organisms	0.80	text
transcription	instance of	all DNA replication events are not only tightly regulated with cell cycle cues but are also coordinated with other cellular events	0.80	text
DNA repair	instance of	all DNA replication events are not only tightly regulated with cell cycle cues but are also coordinated with other cellular events	0.80	text
local DNA topology	instance of	eukaryotic origins do not contain consensus DNA sequence elements but their location is influenced by contextual cues	0.80	text
DNA structural features	instance of	eukaryotic origins do not contain consensus DNA sequence elements but their location is influenced by contextual cues	0.80	text
and chromatin environment.Eukaryotic origin function relies on a conserved initiator protein complex to load replicative helicases onto DNA during the late M	instance of	eukaryotic origins do not contain consensus DNA sequence elements but their location is influenced by contextual cues	0.80	text
G1 phases of the cell cycle	instance of	eukaryotic origins do not contain consensus DNA sequence elements but their location is influenced by contextual cues	0.80	text
a step known as origin licensing	instance of	eukaryotic origins do not contain consensus DNA sequence elements but their location is influenced by contextual cues	0.80	text
Origin of replication	related to Viral	Viruses	0.60	section

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