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PTPN5

Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the PTPN5 gene.

Substrates, Clinical significance & Inhibition

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Substrates

13 related topics

Clinical significance

9 related topics

Inhibition

2 related topics

Overview

3 related topics

Key facts & relationships

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3.1.3.48
Aliases
PTPN5, PTPSTEP, STEP, STEP61, protein tyrosine phosphatase, non-receptor type 5, protein tyrosine phosphatase non-receptor type 5
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BIJ, 2BV5, 2CJZ
Band
11p15.1 · 7 B3|7 30.7 cM
Bgee
endothelial cell · middle temporal gyrus · Brodmann area 23 · nucleus accumbens · putamen
BioGPS
n/a

Topics to explore

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Overview

Substrates

Clinical significance

Inhibition

Advanced semantic analysis

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Map overview Semantic statistics

PTPN5

Nodes32
Edges31
Triples74
Avg. degree1.94
Density0.0625
Components1

How this topic connects Entity context

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PTPN5

Top relations

Bgee · 17
PTPN5 → anterior amygdaloid area, Brodmann area 23, caudate nucleus, endothelial cell, external globus pallidus, globus pallidus, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, middle temporal gyrus, nucleus accumbens, nucleus of stria terminalis, olfactory tubercle, postcentral gyrus, primary visual cortex, putamen, superior frontal gyrus
RNA expression pattern · 17
PTPN5 → anterior amygdaloid area, Brodmann area 23, caudate nucleus, endothelial cell, external globus pallidus, globus pallidus, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, middle temporal gyrus, nucleus accumbens, nucleus of stria terminalis, olfactory tubercle, postcentral gyrus, primary visual cortex, putamen, superior frontal gyrus
Gene ontology · 15
PTPN5 → cellular response to cytokine stimulus, dephosphorylation, endoplasmic reticulum, endoplasmic reticulum membrane, hydrolase activity, integral component of membrane, membrane, nucleoplasm, peptidyl-tyrosine dephosphorylation, phosphatase activity, phosphoprotein phosphatase activity, phosphotyrosine residue binding, protein binding, protein dephosphorylation, protein tyrosine phosphatase activity
Band · 2
PTPN5 → 11p15.1, 7 B3|7 30.7 cM
Chr. · 2
PTPN5 → Chromosome 11 (human), Chromosome 7 (mouse)
End · 2
PTPN5 → 18,792,721 bp, 46,783,432 bp
3.1.3.48 · 1
PTPN5 → ↗
Aliases · 1
PTPN5 → PTPN5, PTPSTEP, STEP, STEP61, protein tyrosine phosphatase, non-receptor type 5, protein tyrosine phosphatase non-receptor type 5
Available structures · 1
PTPN5 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BIJ, 2BV5, 2CJZ
BioGPS · 1
PTPN5 → n/a

Important terminology Word statistics

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Important terminology

step gene tyrosine human protein bp chromosome chr band phosphatase several 11 mouse non-receptor type fyn also activity dephosphorylation location

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PTPN53.1.3.481.00infobox
PTPN5AliasesPTPN5, PTPSTEP, STEP, STEP61, protein tyrosine phosphatase, non-receptor type 5, protein tyrosine phosphatase non-receptor type 51.00infobox
PTPN5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BIJ, 2BV5, 2CJZ1.00infobox
PTPN5Band11p15.11.00infobox
PTPN5Band7 B3|7 30.7 cM1.00infobox
PTPN5Bgeeendothelial cell1.00infobox
PTPN5Bgeemiddle temporal gyrus1.00infobox
PTPN5BgeeBrodmann area 231.00infobox
PTPN5Bgeenucleus accumbens1.00infobox
PTPN5Bgeeputamen1.00infobox
PTPN5Bgeeprimary visual cortex1.00infobox
PTPN5Bgeecaudate nucleus1.00infobox
PTPN5Bgeeexternal globus pallidus1.00infobox
PTPN5Bgeesuperior frontal gyrus1.00infobox
PTPN5Bgeepostcentral gyrus1.00infobox
PTPN5Bgeeolfactory tubercle1.00infobox
PTPN5Bgeelateral septal nucleus1.00infobox
PTPN5Bgeeglobus pallidus1.00infobox
PTPN5Bgeeanterior amygdaloid area1.00infobox
PTPN5Bgeenucleus of stria terminalis1.00infobox
PTPN5Bgeemedial dorsal nucleus1.00infobox
PTPN5Bgeelateral geniculate nucleus1.00infobox
PTPN5BioGPSn/a1.00infobox
PTPN5Chr.Chromosome 11 (human)1.00infobox
PTPN5Chr.Chromosome 7 (mouse)1.00infobox
PTPN5DatabasesNCBI: entry; OMA: entry1.00infobox
PTPN5End18,792,721 bp1.00infobox
PTPN5End46,783,432 bp1.00infobox
PTPN5EnsemblENSG000001107861.00infobox
PTPN5Entrez848671.00infobox

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