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Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the PTPN5 gene.
The analysis highlights Substrates, Clinical significance and Inhibition as prominent areas in the source structure around PTPN5.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PTPN5 shows recurring relationship patterns in the source. For example, PTPN5 → anterior amygdaloid area, Brodmann area 23, caudate nucleus, endothelial cell, external globus pallidus, globus pallidus, lateral geniculate nucleus, lateral septal nucleus, medial dorsal nucleus, middle temporal gyrus, nucleus accumbens, nucleus of stria terminalis, olfactory tubercle, postcentral gyrus, primary visual cortex, putamen, superior frontal gyrus Another extracted example is PTPN5 → cellular response to cytokine stimulus, dephosphorylation, endoplasmic reticulum, endoplasmic reticulum membrane, hydrolase activity, integral component of membrane, membrane, nucleoplasm, peptidyl-tyrosine dephosphorylation, phosphatase activity, phosphoprotein phosphatase activity, phosphotyrosine residue binding, protein binding, protein dephosphorylation, protein tyrosine phosphatase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
step gene tyrosine human protein bp chromosome chr band phosphatase several 11 mouse non-receptor type fyn also activity dephosphorylation location
TTTA extracted 74 structured relationships around PTPN5. Examples in this analysis include PTPN5 → 3.1.3.48 → ↗ and PTPN5 → Aliases → PTPN5, PTPSTEP, STEP, STEP61, protein tyrosine phosphatase, non-receptor type 5, protein tyrosine phosphatase non-receptor type 5. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PTPN5 | 3.1.3.48 | ↗ | 1.00 | infobox |
| PTPN5 | Aliases | PTPN5, PTPSTEP, STEP, STEP61, protein tyrosine phosphatase, non-receptor type 5, protein tyrosine phosphatase non-receptor type 5 | 1.00 | infobox |
| PTPN5 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BIJ, 2BV5, 2CJZ | 1.00 | infobox |
| PTPN5 | Band | 11p15.1 | 1.00 | infobox |
| PTPN5 | Band | 7 B3|7 30.7 cM | 1.00 | infobox |
| PTPN5 | Bgee | endothelial cell | 1.00 | infobox |
| PTPN5 | Bgee | middle temporal gyrus | 1.00 | infobox |
| PTPN5 | Bgee | Brodmann area 23 | 1.00 | infobox |
| PTPN5 | Bgee | nucleus accumbens | 1.00 | infobox |
| PTPN5 | Bgee | putamen | 1.00 | infobox |
| PTPN5 | Bgee | primary visual cortex | 1.00 | infobox |
| PTPN5 | Bgee | caudate nucleus | 1.00 | infobox |
| PTPN5 | Bgee | external globus pallidus | 1.00 | infobox |
| PTPN5 | Bgee | superior frontal gyrus | 1.00 | infobox |
| PTPN5 | Bgee | postcentral gyrus | 1.00 | infobox |
| PTPN5 | Bgee | olfactory tubercle | 1.00 | infobox |
| PTPN5 | Bgee | lateral septal nucleus | 1.00 | infobox |
| PTPN5 | Bgee | globus pallidus | 1.00 | infobox |
| PTPN5 | Bgee | anterior amygdaloid area | 1.00 | infobox |
| PTPN5 | Bgee | nucleus of stria terminalis | 1.00 | infobox |
| PTPN5 | Bgee | medial dorsal nucleus | 1.00 | infobox |
| PTPN5 | Bgee | lateral geniculate nucleus | 1.00 | infobox |
| PTPN5 | BioGPS | n/a | 1.00 | infobox |
| PTPN5 | Chr. | Chromosome 11 (human) | 1.00 | infobox |
| PTPN5 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| PTPN5 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PTPN5 | End | 18,792,721 bp | 1.00 | infobox |
| PTPN5 | End | 46,783,432 bp | 1.00 | infobox |
| PTPN5 | Ensembl | ENSG00000110786 | 1.00 | infobox |
| PTPN5 | Entrez | 84867 | 1.00 | infobox |
The concept neighborhoods around PTPN5 bring nearby vocabulary together. In this analysis, examples include External, Search and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PTPN5, one of the stronger structural bridges in this analysis connects PTPN5 with Substrates. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PTPN5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Substrates, Clinical significance & Inhibition, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PTPN5 · EN edition · Analysis: TopicsToTalkAbout