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Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene.
The analysis highlights Interactions and Overview as prominent areas in the source structure around PTPN12.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around PTPN12 shows recurring relationship patterns in the source. For example, PTPN12 → cell junction, cell projection, cellular response to cytokine stimulus, cellular response to epidermal growth factor stimulus, cytoplasm, cytosol, dephosphorylation, ERBB2 signaling pathway, focal adhesion, hydrolase activity, negative regulation of ERBB signaling pathway, negative regulation of platelet-derived growth factor receptor-beta signaling pathway, non-membrane spanning protein tyrosine phosphatase activity, nucleoplasm, peptidyl-tyrosine dephosphorylation, phosphatase activity, phosphoprotein phosphatase activity, podosome, protein binding, protein dephosphorylation Another extracted example is PTPN12 → abdominal wall, Achilles tendon, dermis, epithelium of colon, genital tubercle, gonad, Gonadal ridge, hair follicle, left lung lobe, lower lobe of lung, monocyte, otic placode, right lung, stroma of bone marrow, subcutaneous adipose tissue, tail of embryo, tibial nerve, trigeminal ganglion, upper lobe of left lung, upper lobe of lung. Use these groups to spot repeated connection types before inspecting the individual relationships.
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gene bp ptp chr human band phosphatase protein chromosome cell tyrosine location encoded molecules may dephosphorylate enzyme mouse interact pstpip1
TTTA extracted 95 structured relationships around PTPN12. Examples in this analysis include PTPN12 → 3.1.3.48 → ↗ and PTPN12 → Aliases → PTPN12, PTP-PEST, PTPG1, protein tyrosine phosphatase, non-receptor type 12, protein tyrosine phosphatase non-receptor type 12. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PTPN12 | 3.1.3.48 | ↗ | 1.00 | infobox |
| PTPN12 | Aliases | PTPN12, PTP-PEST, PTPG1, protein tyrosine phosphatase, non-receptor type 12, protein tyrosine phosphatase non-receptor type 12 | 1.00 | infobox |
| PTPN12 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5J8R | 1.00 | infobox |
| PTPN12 | Band | 7q11.23 | 1.00 | infobox |
| PTPN12 | Band | 5|5 A3 | 1.00 | infobox |
| PTPN12 | Bgee | gonad | 1.00 | infobox |
| PTPN12 | Bgee | epithelium of colon | 1.00 | infobox |
| PTPN12 | Bgee | monocyte | 1.00 | infobox |
| PTPN12 | Bgee | right lung | 1.00 | infobox |
| PTPN12 | Bgee | tibial nerve | 1.00 | infobox |
| PTPN12 | Bgee | Achilles tendon | 1.00 | infobox |
| PTPN12 | Bgee | lower lobe of lung | 1.00 | infobox |
| PTPN12 | Bgee | upper lobe of lung | 1.00 | infobox |
| PTPN12 | Bgee | upper lobe of left lung | 1.00 | infobox |
| PTPN12 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| PTPN12 | Bgee | tail of embryo | 1.00 | infobox |
| PTPN12 | Bgee | Gonadal ridge | 1.00 | infobox |
| PTPN12 | Bgee | left lung lobe | 1.00 | infobox |
| PTPN12 | Bgee | genital tubercle | 1.00 | infobox |
| PTPN12 | Bgee | stroma of bone marrow | 1.00 | infobox |
| PTPN12 | Bgee | trigeminal ganglion | 1.00 | infobox |
| PTPN12 | Bgee | abdominal wall | 1.00 | infobox |
| PTPN12 | Bgee | otic placode | 1.00 | infobox |
| PTPN12 | Bgee | hair follicle | 1.00 | infobox |
| PTPN12 | Bgee | dermis | 1.00 | infobox |
| PTPN12 | BioGPS | More reference expression data | 1.00 | infobox |
| PTPN12 | Chr. | Chromosome 7 (human) | 1.00 | infobox |
| PTPN12 | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| PTPN12 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PTPN12 | End | 77,640,069 bp | 1.00 | infobox |
The concept neighborhoods around PTPN12 bring nearby vocabulary together. In this analysis, examples include Activity, Search and Type. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PTPN12, one of the stronger structural bridges in this analysis connects PTPN12 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PTPN12 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PTPN12 · EN edition · Analysis: TopicsToTalkAbout
