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PTPN12

Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene.

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3.1.3.48
Aliases
PTPN12, PTP-PEST, PTPG1, protein tyrosine phosphatase, non-receptor type 12, protein tyrosine phosphatase non-receptor type 12
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5J8R
Band
7q11.23 · 5|5 A3
Bgee
gonad · epithelium of colon · monocyte · right lung · tibial nerve
BioGPS
More reference expression data

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PTPN12

Nodes13
Edges12
Triples95
Avg. degree1.85
Density0.153846
Components1

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PTPN12

Top relations

Gene ontology · 24
PTPN12 → cell junction, cell projection, cellular response to cytokine stimulus, cellular response to epidermal growth factor stimulus, cytoplasm, cytosol, dephosphorylation, ERBB2 signaling pathway, focal adhesion, hydrolase activity, negative regulation of ERBB signaling pathway, negative regulation of platelet-derived growth factor receptor-beta signaling pathway, non-membrane spanning protein tyrosine phosphatase activity, nucleoplasm, peptidyl-tyrosine dephosphorylation, phosphatase activity, phosphoprotein phosphatase activity, podosome, protein binding, protein dephosphorylation
Bgee · 20
PTPN12 → abdominal wall, Achilles tendon, dermis, epithelium of colon, genital tubercle, gonad, Gonadal ridge, hair follicle, left lung lobe, lower lobe of lung, monocyte, otic placode, right lung, stroma of bone marrow, subcutaneous adipose tissue, tail of embryo, tibial nerve, trigeminal ganglion, upper lobe of left lung, upper lobe of lung
RNA expression pattern · 20
PTPN12 → abdominal wall, Achilles tendon, dermis, epithelium of colon, genital tubercle, gonad, Gonadal ridge, hair follicle, left lung lobe, lower lobe of lung, monocyte, otic placode, right lung, stroma of bone marrow, subcutaneous adipose tissue, tail of embryo, tibial nerve, trigeminal ganglion, upper lobe of left lung, upper lobe of lung
related to Interactions · 6
PTPN12 → BCAR1, Grb2, Paxillin, PSTPIP1, SHC1, TGFB1I1
Band · 2
PTPN12 → 5|5 A3, 7q11.23
Chr. · 2
PTPN12 → Chromosome 5 (mouse), Chromosome 7 (human)
End · 2
PTPN12 → 21,055,911 bp, 77,640,069 bp
3.1.3.48 · 1
PTPN12 → ↗
Aliases · 1
PTPN12 → PTPN12, PTP-PEST, PTPG1, protein tyrosine phosphatase, non-receptor type 12, protein tyrosine phosphatase non-receptor type 12
Available structures · 1
PTPN12 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5J8R

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Important terminology

gene bp ptp chr human band phosphatase protein chromosome cell tyrosine location encoded molecules may dephosphorylate enzyme mouse interact pstpip1

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PTPN123.1.3.481.00infobox
PTPN12AliasesPTPN12, PTP-PEST, PTPG1, protein tyrosine phosphatase, non-receptor type 12, protein tyrosine phosphatase non-receptor type 121.00infobox
PTPN12Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5J8R1.00infobox
PTPN12Band7q11.231.00infobox
PTPN12Band5|5 A31.00infobox
PTPN12Bgeegonad1.00infobox
PTPN12Bgeeepithelium of colon1.00infobox
PTPN12Bgeemonocyte1.00infobox
PTPN12Bgeeright lung1.00infobox
PTPN12Bgeetibial nerve1.00infobox
PTPN12BgeeAchilles tendon1.00infobox
PTPN12Bgeelower lobe of lung1.00infobox
PTPN12Bgeeupper lobe of lung1.00infobox
PTPN12Bgeeupper lobe of left lung1.00infobox
PTPN12Bgeesubcutaneous adipose tissue1.00infobox
PTPN12Bgeetail of embryo1.00infobox
PTPN12BgeeGonadal ridge1.00infobox
PTPN12Bgeeleft lung lobe1.00infobox
PTPN12Bgeegenital tubercle1.00infobox
PTPN12Bgeestroma of bone marrow1.00infobox
PTPN12Bgeetrigeminal ganglion1.00infobox
PTPN12Bgeeabdominal wall1.00infobox
PTPN12Bgeeotic placode1.00infobox
PTPN12Bgeehair follicle1.00infobox
PTPN12Bgeedermis1.00infobox
PTPN12BioGPSMore reference expression data1.00infobox
PTPN12Chr.Chromosome 7 (human)1.00infobox
PTPN12Chr.Chromosome 5 (mouse)1.00infobox
PTPN12DatabasesNCBI: entry; OMA: entry1.00infobox
PTPN12End77,640,069 bp1.00infobox

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