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Prp8

Prp8 refers to both the Prp8 protein and Prp8 gene. Prp8's name originates from its involvement in pre-mRNA processing. The Prp8 protein is a large, highly conserved, and unique protein that resides in the catalytic core of the spliceosome and has been found to have a central role in molecular rearrangements that occur there. Prp8 protein is a major…

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Role in splicing, Mutation and disease & Overview

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Key facts & relationships

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Alt. symbols
USA2, DBF3, DNA39, RNA8, SLT21
Domains
InterPro
PDB
4I43
Search for
Search forStructuresSwiss-modelDomainsInterPro
Structures
Swiss-model
Symbol
PRP8

Topics to explore

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Overview

Role in splicing

Mutation and disease

Advanced semantic analysis

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Map overview Semantic statistics

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Prp8

Nodes27
Edges26
Triples54
Avg. degree1.93
Density0.074074
Components1

How this topic connects Entity context

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Prp8

Top relations

related to Role in splicing · 23
Prp8 → All, C-terminus, Common, Complex, DNA, Group II, II, In, JAB, MPN, NLS, Pre-mRNA, RNA, RNA-protein, The, The Prp8, The U5, The U5-U4/U6, There, This
related to Phenotype mutations of Prp8 across species · 12
Prp8 → Caenorhabditis, In, Mouse Prp8, Mutations, Retinitis Pigmentosa, RNA, RNA Interference, RNAi, The U5, This, U5, Yeast Prp8
related to Deficiencies · 8
Prp8 → Brr2p, C-terminus, Retinitis Pigmentosa, SS, Studies, This, U1, U4/U6 RNA
related to history · 4
Prp8 → The, The Prp8, VIII, YHR165C
Alt. symbols · 1
Prp8 → USA2, DBF3, DNA39, RNA8, SLT21
Domains · 1
Prp8 → InterPro
PDB · 1
Prp8 → 4I43
Search for · 1
Prp8 → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Prp8 → Swiss-model
Symbol · 1
Prp8 → PRP8

Important terminology Word statistics

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Important terminology

spliceosome protein splicing snrnp rna mrna catalytic u5 introns core mutation mutations also exons involved gene complex central structure yeast

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
Prp8Alt. symbolsUSA2, DBF3, DNA39, RNA8, SLT211.00infobox
Prp8DomainsInterPro1.00infobox
Prp8PDB4I431.00infobox
Prp8Search forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Prp8StructuresSwiss-model1.00infobox
Prp8SymbolPRP81.00infobox
Prp8UniProtP333341.00infobox
Prp8related to DeficienciesRetinitis Pigmentosa0.60section
Prp8related to DeficienciesThis0.60section
Prp8related to DeficienciesC-terminus0.60section
Prp8related to DeficienciesStudies0.60section
Prp8related to DeficienciesBrr2p0.60section

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