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Proteinopathy

A proteinopathy ([pref. protein]; -pathy [suff. disease]; proteinopathies pl.; proteinopathic adj), or proteopathy, protein conformational disorder, or protein misfolding disease, is a class of diseases in which certain proteins become misfolded. The structurally abnormal proteins disrupt the function of cells in tissues and organs.

Standards, Pathophysiology & Management

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Pathophysiology

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Proteinopathy

Nodes81
Edges80
Triples4
Avg. degree1.98
Density0.024691
Components1

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Important terminology

protein proteins amyloid amyloidosis disease alzheimer's form proteinopathies prion aβ cerebral proteopathy diseases cells molecules organs example proteopathies misfolding multiple

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
small interfering RNAsinstance ofincluding small molecules and biologic medicines0.80text
antisense oligonucleotidesinstance ofincluding small molecules and biologic medicines0.80text
peptidesinstance ofincluding small molecules and biologic medicines0.80text
and engineered immune cellsinstance ofincluding small molecules and biologic medicines0.80text

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