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RecA: History, Function & Overview

RecA is a 38 kilodalton protein essential for the repair and maintenance of DNA in bacteria. It functions as a recombinase and strand-exchange protein, catalyzing the central steps of homologous recombination by forming nucleoprotein filaments on single-stranded DNA. Structural and functional homologs to RecA have been found in all kingdoms of life. RecA…

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RecA topic overview

The analysis highlights History, Function and Overview as prominent areas in the source structure around RecA.

Related topics
35
Source areas
5
Connected nodes
40
Extracted relationships
55
Concept neighborhoods
19
Bridge connections
40

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 16 topics
Function · 11 topics
Structure · 5 topics
History · 2 topics
Clinical significance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR013765 · PF00154
Available protein structures:
IPR013765 · PF00154
InterPro
IPR013765
PDB
IPR013765 PF00154 (ECOD; PDBsum)
Pfam
PF00154
Pfam clan
CL0023

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How RecA connects Entity context

The extracted context around RecA shows recurring relationship patterns in the source. For example, RecA → ATP, ATPase, C-terminal, CAD, CTD, DNA, DNA-binding, L1, L2, N-terminal, NTD, P-loop, RecA/RAD51/RadA, The, The CAD, The CTD, The NTD, Walker Another extracted example is RecA → Alvin, Ann Dee Margulies, Clark, In, Kevin McEntee, Later, Purification, RecBCD, RecF, Shortly, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

RecA

Top relations

related to Structure · 18
RecA → ATP, ATPase, C-terminal, CAD, CTD, DNA, DNA-binding, L1, L2, N-terminal, NTD, P-loop, RecA/RAD51/RadA, The, The CAD, The CTD, The NTD, Walker
related to history · 11
RecA → Alvin, Ann Dee Margulies, Clark, In, Kevin McEntee, Later, Purification, RecBCD, RecF, Shortly, The
related to Homologous recombination · 7
RecA → ATP, In, The, The RecA, This, When, Witkor
related to Clinical significance · 4
RecA → DNA, Inhibitors, Since, Small
related to Natural transformation · 3
RecA → DNA, In, Natural
AlphaFold · 2
RecA → IPR013765, PF00154
Available protein structures: · 2
RecA → IPR013765, PF00154
InterPro · 1
RecA → IPR013765
PDB · 1
RecA → IPR013765 PF00154 (ECOD; PDBsum)
Pfam · 1
RecA → PF00154

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dna protein filament homologous repair recombination atp structure homology bacterial functions recombinase bacteria nucleoprotein transformation coli dsdna search form first

RecA relationships Subject–Predicate–Object triples

TTTA extracted 55 structured relationships around RecA. Examples in this analysis include RecA → AlphaFold → IPR013765 and RecA → AlphaFold → PF00154. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
RecAAlphaFoldIPR0137651.00infobox
RecAAlphaFoldPF001541.00infobox
RecAAvailable protein structures:IPR0137651.00infobox
RecAAvailable protein structures:PF001541.00infobox
RecAInterProIPR0137651.00infobox
RecAPDBIPR013765 PF00154 (ECOD; PDBsum)1.00infobox
RecAPfamPF001541.00infobox
RecAPfam clanCL00231.00infobox
RecAPROSITEPDOC001311.00infobox
RecASCOP22reb / SCOPe / SUPFAM1.00infobox
RecASymbolRecA1.00infobox
RecAis a38 kilodalton protein essential for the repair and maintenance of DNA in bacteria0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around RecA bring nearby vocabulary together. In this analysis, examples include Dna, Atp and Filament. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • RecA
    • Dna
    • Atp
    • Filament
    • Homologous
    • Repair
    • Recombination
    • Bacteria
    • Crystal
    • Structure
    • Transformation
    • Bacterial
    • Coli
  • reca
    • Dna
    • Atp
    • Filament
    • Homologous
    • Repair
    • Recombination
    • Bacteria
    • Crystal
    • Structure
    • Transformation
    • Bacterial
    • Coli
  • protein
    • Central
    • Dna
    • Rad51
    • Rada
    • Reca
    • Crystal
    • Functions
    • Homologous
    • Nucleoprotein
    • Structure
    • First
    • Recombination
  • dna
    • Repair
    • Homologous
    • Reca
    • Recombination
    • Protein
    • Coli
    • Atp
    • Homology
    • Central
    • Recombinase
    • Steps
    • Bacteria
  • dna repair
    • Repair
    • Homologous
    • Reca
    • Recombination
    • Protein
    • Coli
    • Atp
    • Homology
    • Steps
    • Central
    • Recombinase
    • Also
  • atp
    • Atpase
    • Binding
    • Bound
    • Form
    • Dna
    • Domain
    • Filament
    • Residues
    • Reca
    • Central
    • Pdb
    • Rad51
  • dna replication
    • Repair
    • Homologous
    • Reca
    • Recombination
    • Protein
    • Coli
    • Atp
    • Homology
    • Central
    • Recombinase
    • Steps
    • Bacteria
  • homologous recombination
    • Recombination
    • Coli
    • Repair
    • Transformation
    • Recombinase
    • Steps
    • Protein
    • Reca
    • Also
    • Crystal
    • Gene
    • Structure

Connections between topic areas Semantic bridges

For RecA, one of the stronger structural bridges in this analysis connects RecA with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
RecA — Overview · splits 24 ⟂ 17
RecA — Function · splits 29 ⟂ 12
RecA — Structure · splits 35 ⟂ 6
RecA — History · splits 38 ⟂ 3

Map overview Semantic statistics

RecA

Nodes41
Edges40
Triples55
Avg. degree1.95
Density0.04878
Components1

Source & methodology

TTTA analyzes the structure around RecA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — RecA · EN edition · Analysis: TopicsToTalkAbout

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