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RecA

RecA is a 38 kilodalton protein essential for the repair and maintenance of DNA in bacteria. It functions as a recombinase and strand-exchange protein, catalyzing the central steps of homologous recombination by forming nucleoprotein filaments on single-stranded DNA. Structural and functional homologs to RecA have been found in all kingdoms of life. RecA…

History, Function & Overview

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Function

SynapsisATPaseATPAssociates more tightlyADP
11 related topics

History

RecBCDRecF
2 related topics

Overview

KilodaltonProteinDNABacteriaRecombinase
16 related topics

Structure

N-terminalWalker motifsC-terminal domainSsDNAB-form
5 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR013765 · PF00154
Available protein structures:
IPR013765 · PF00154
InterPro
IPR013765
PDB
IPR013765 PF00154 (ECOD; PDBsum)
Pfam
PF00154
Pfam clan
CL0023

Topics to explore

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Overview

Structure

Function

Clinical significance

History

Advanced semantic analysis

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Map overview Semantic statistics

RecA

Nodes41
Edges40
Triples55
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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RecA

Top relations

related to Structure · 18
RecA → ATP, ATPase, C-terminal, CAD, CTD, DNA, DNA-binding, L1, L2, N-terminal, NTD, P-loop, RecA/RAD51/RadA, The, The CAD, The CTD, The NTD, Walker
related to history · 11
RecA → Alvin, Ann Dee Margulies, Clark, In, Kevin McEntee, Later, Purification, RecBCD, RecF, Shortly, The
related to Homologous recombination · 7
RecA → ATP, In, The, The RecA, This, When, Witkor
related to Clinical significance · 4
RecA → DNA, Inhibitors, Since, Small
related to Natural transformation · 3
RecA → DNA, In, Natural
AlphaFold · 2
RecA → IPR013765, PF00154
Available protein structures: · 2
RecA → IPR013765, PF00154
InterPro · 1
RecA → IPR013765
PDB · 1
RecA → IPR013765 PF00154 (ECOD; PDBsum)
Pfam · 1
RecA → PF00154

Important terminology Word statistics

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Important terminology

dna protein filament homologous repair recombination atp structure homology bacterial functions recombinase bacteria nucleoprotein transformation coli dsdna search form first

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RecAAlphaFoldIPR0137651.00infobox
RecAAlphaFoldPF001541.00infobox
RecAAvailable protein structures:IPR0137651.00infobox
RecAAvailable protein structures:PF001541.00infobox
RecAInterProIPR0137651.00infobox
RecAPDBIPR013765 PF00154 (ECOD; PDBsum)1.00infobox
RecAPfamPF001541.00infobox
RecAPfam clanCL00231.00infobox
RecAPROSITEPDOC001311.00infobox
RecASCOP22reb / SCOPe / SUPFAM1.00infobox
RecASymbolRecA1.00infobox
RecAis a38 kilodalton protein essential for the repair and maintenance of DNA in bacteria0.90text

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    Min side: 3
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