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Protein splicing

Protein splicing is an intramolecular reaction of a particular protein in which an internal protein segment (called an intein) is removed from a precursor protein with a ligation of C-terminal and N-terminal external proteins (called exteins) on both sides. The splicing junction of the precursor protein is mainly a cysteine or a serine, which are amino…

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Overview

History

Mechanism

Intein

Applications in biotechnology

Applications in antimicrobial development

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Map overview Semantic statistics

Protein splicing

Nodes101
Edges100
Triples35
Avg. degree1.98
Density0.019802
Components1

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Protein splicing

Top relations

related to history · 15
Protein splicing → Anraku, ATPase, C-termini, DNA, Hirata, HO, In, Neurospora, Protein, Saccharomyces, Since, Stevens, The, They, VMA1
related to External links · 7
Protein splicing → Intein, Medicine Medical Subject Headings, MeSH, National Library, PL, Splicing, The Intein DatabaseShmuel Pietrokovski's
has application · 5
Protein splicing → AAs, Inteins, NMR, Pharmaceutical, There
related to Intein · 3
Protein splicing → An, Inteins, RNA
is a · 1
Protein splicing → intramolecular reaction of a particular protein in which an internal protein segment

Important terminology Word statistics

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Important terminology

protein intein inteins splicing proteins found first c-extein gene residue also n-extein precursor example peptide intein-containing class used called side

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Protein splicingis aintramolecular reaction of a particular protein in which an internal protein segment0.90text
adenosine triphosphateinstance ofThe protein splicing reactions which are known now do not require exogenous cofactors or energy sources0.80text
protein semisynthesisinstance ofInteins have been engineered for particular applications0.80text
the selective labeling of protein segmentsinstance ofInteins have been engineered for particular applications0.80text
which is useful for NMR studies of large proteins.Pharmaceutical inhibition of intein excision may be a useful tool for drug developmentinstance ofInteins have been engineered for particular applications0.80text
Protein splicinghas applicationInteins0.60section
Protein splicinghas applicationThere0.60section
Protein splicinghas applicationAAs0.60section
Protein splicinghas applicationNMR0.60section
Protein splicinghas applicationPharmaceutical0.60section
Protein splicingrelated to External linksThe Intein DatabaseShmuel Pietrokovski's0.60section
Protein splicingrelated to External linksIntein0.60section

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