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Apafant: Products & Overview

Apafant (WEB-2086, LSM-2613) is a drug which acts as a potent and selective inhibitor of the phospholipid mediator platelet-activating factor (PAF). It was developed by structural modification of the thienotriazolodiazepine sedative drug brotizolam and demonstrated that PAF inhibitory actions could be separated from activity at the benzodiazepine…

Language: English [EN]
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Apafant topic overview

The analysis highlights Products and Overview as prominent areas in the source structure around Apafant.

Related topics
8
Source areas
1
Connected nodes
9
Extracted relationships
36
Concept neighborhoods
9
Bridge connections
9

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 8 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
CAS Number
105219-56-5
ChEBI
CHEBI:92490
ChEMBL
ChEMBL280164
ChemSpider
59298
CompTox Dashboard (EPA)
DTXSID5048974

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Apafant connects Entity context

The extracted context around Apafant shows recurring relationship patterns in the source. For example, Apafant → Acid Methyl Ester, Amino-3, Carbomethoxyethyl, Chlorobenzoylacetonitrile, Chlorophenyl, Condensation, Construction, Dan’s, Diethyl, Ester, Heating, Methyl, PC136015497, PC13670761, PC13670766, PC88403880, Precursor, Reaction, Saponification, The Another extracted example is Apafant → Interactive image. Use these groups to spot repeated connection types before inspecting the individual relationships.

Apafant

Top relations

related to Synthesis · 20
Apafant → Acid Methyl Ester, Amino-3, Carbomethoxyethyl, Chlorobenzoylacetonitrile, Chlorophenyl, Condensation, Construction, Dan’s, Diethyl, Ester, Heating, Methyl, PC136015497, PC13670761, PC13670766, PC88403880, Precursor, Reaction, Saponification, The
3D model (JSmol) · 1
Apafant → Interactive image
CAS Number · 1
Apafant → 105219-56-5
ChEBI · 1
Apafant → CHEBI:92490
ChEMBL · 1
Apafant → ChEMBL280164
ChemSpider · 1
Apafant → 59298
CompTox Dashboard (EPA) · 1
Apafant → DTXSID5048974
ECHA InfoCard · 1
Apafant → 100.220.442
Formula · 1
Apafant → C22H22ClN5O2S
IUPHAR/BPS · 1
Apafant → 1859

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

2-chlorophenyl drug paf synthesis 3- 2-chlorobenzoyl methyl amide 4- -9-methyl-6h-thieno 2-f triazolo 3-a phospholipid thienotriazolodiazepine sedative brotizolam asthma conjunctivitis reaction

Apafant relationships Subject–Predicate–Object triples

TTTA extracted 36 structured relationships around Apafant. Examples in this analysis include Apafant → 3D model (JSmol) → Interactive image and Apafant → CAS Number → 105219-56-5. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Apafant3D model (JSmol)Interactive image1.00infobox
ApafantCAS Number105219-56-51.00infobox
ApafantChEBICHEBI:924901.00infobox
ApafantChEMBLChEMBL2801641.00infobox
ApafantChemSpider592981.00infobox
ApafantCompTox Dashboard (EPA)DTXSID50489741.00infobox
ApafantECHA InfoCard100.220.4421.00infobox
ApafantFormulaC22H22ClN5O2S1.00infobox
ApafantIUPHAR/BPS18591.00infobox
ApafantKEGGD016521.00infobox
ApafantMolar mass455.96 g·mol−11.00infobox
ApafantPubChem CID658891.00infobox
ApafantUNIIJ613NI05SV1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Apafant bring nearby vocabulary together. In this analysis, examples include Synthesis, Acts and Asthma. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Apafant
    • Synthesis
    • Acts
    • Asthma
    • Conjunctivitis
    • Inhibitor
    • Lsm-2613
    • Mediator
    • Phospholipid
    • Platelet-activating
    • Potent
    • Selective
    • Web-2086
  • apafant
    • Synthesis
    • Acts
    • Asthma
    • Conjunctivitis
    • Inhibitor
    • Lsm-2613
    • Mediator
    • Phospholipid
    • Platelet-activating
    • Potent
    • Selective
    • Web-2086
  • phospholipid
    • Mediator
    • Platelet-activating
    • Potent
    • Selective
    • Web-2086
    • Paf
  • platelet-activating factor
    • Potent
    • Selective
    • Web-2086
    • Paf
  • thienotriazolodiazepine
    • Brotizolam
    • Sedative
    • Drug
    • Paf
  • brotizolam
    • Sedative
    • Thienotriazolodiazepine
    • Drug
    • Paf
  • sedative
    • Brotizolam
    • Thienotriazolodiazepine
  • conjunctivitis
    • Asthma
    • Apafant

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Apafant map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Apafant

Nodes10
Edges9
Triples36
Avg. degree1.8
Density0.2
Components1

Source & methodology

TTTA analyzes the structure around Apafant to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Products & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Apafant · EN edition · Analysis: TopicsToTalkAbout

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