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PER3

The PER3 gene encodes the period circadian protein homolog 3 protein in humans. PER3 is a paralog to the PER1 and PER2 genes. It is a circadian gene associated with delayed sleep phase syndrome in humans.

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Aliases
PER3, GIG13, FASPS3, period circadian clock 3, period circadian regulator 3
Band
1p36.23 · 4|4 E2
Bgee
sural nerve · parietal pleura · cerebellar vermis · tibia · cerebellar hemisphere
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

History

Function

Role in chronobiology

Animal studies

Clinical significance

Gene

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Map overview Semantic statistics

PER3

Nodes32
Edges31
Triples141
Avg. degree1.94
Density0.0625
Components1

How this topic connects Entity context

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PER3

Top relations

Bgee · 20
PER3 → Achilles tendon, cerebellar hemisphere, cerebellar vermis, ciliary body, gastric mucosa, lacrimal gland, neural layer of retina, parietal pleura, primary oocyte, right hemisphere of cerebellum, Rostral migratory stream, saccule, secondary oocyte, Skeletal muscle tissue of rectus abdominis, skin of external ear, superior frontal gyrus, sural nerve, tibia, vestibular membrane of cochlear duct, visceral pleura
RNA expression pattern · 20
PER3 → Achilles tendon, cerebellar hemisphere, cerebellar vermis, ciliary body, gastric mucosa, lacrimal gland, neural layer of retina, parietal pleura, primary oocyte, right hemisphere of cerebellum, Rostral migratory stream, saccule, secondary oocyte, Skeletal muscle tissue of rectus abdominis, skin of external ear, superior frontal gyrus, sural nerve, tibia, vestibular membrane of cochlear duct, visceral pleura
Gene ontology · 18
PER3 → circadian regulation of gene expression, circadian rhythm, cytoplasm, entrainment of circadian clock by photoperiod, kinase binding, negative regulation of transcription by RNA polymerase II, nucleus, protein binding, protein stabilization, regulation of circadian sleep/wake cycle, sleep, regulation of transcription, DNA-templated, response to light stimulus, rhythmic process, transcription cis-regulatory region binding, transcription corepressor binding, transcription factor binding, transcription, DNA-templated, ubiquitin protein ligase binding
related to Role in chronobiology · 11
PER3 → However, Likely, PAS, Per1, PER1/2, Per2, SCN, The, The RNA, This, Unlike Per1
related to Function · 9
PER3 → Circadian, Genes, It, PER1, PER2, PER3-P415A/H417R, Period, SCN, This
related to history · 9
PER3 → Harvard Medical School, June, Kobe University School, Medicine, PER, Per2, PERIOD3, The, The Per3
related to Clinical significance · 7
PER3 → AB047686, Additionally, GenBank, T2DM, The, The PER3, The PER3-P415A/H417R
related to Post translational modifications · 7
PER3 → CSNK1E, Modification, PER1, Phosphorylation, PhosphoSitePlusModification, The, Ubiquitinated
related to Animal studies · 6
PER3 → Functional Per3, Furthermore, PER1, Per1-/-Per2, PER2, While
related to External links · 6
PER3 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library

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Important terminology

circadian gene per1 per2 bp protein human clock polymorphism light period chr band location mper3 chromosome sleep scn genes mice

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PER3AliasesPER3, GIG13, FASPS3, period circadian clock 3, period circadian regulator 31.00infobox
PER3Band1p36.231.00infobox
PER3Band4|4 E21.00infobox
PER3Bgeesural nerve1.00infobox
PER3Bgeeparietal pleura1.00infobox
PER3Bgeecerebellar vermis1.00infobox
PER3Bgeetibia1.00infobox
PER3Bgeecerebellar hemisphere1.00infobox
PER3BgeeAchilles tendon1.00infobox
PER3Bgeeright hemisphere of cerebellum1.00infobox
PER3Bgeevisceral pleura1.00infobox
PER3Bgeegastric mucosa1.00infobox
PER3BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
PER3Bgeeciliary body1.00infobox
PER3Bgeevestibular membrane of cochlear duct1.00infobox
PER3Bgeeneural layer of retina1.00infobox
PER3Bgeesaccule1.00infobox
PER3BgeeRostral migratory stream1.00infobox
PER3Bgeeprimary oocyte1.00infobox
PER3Bgeeskin of external ear1.00infobox
PER3Bgeesuperior frontal gyrus1.00infobox
PER3Bgeelacrimal gland1.00infobox
PER3Bgeesecondary oocyte1.00infobox
PER3BioGPSMore reference expression data1.00infobox
PER3Chr.Chromosome 1 (human)1.00infobox
PER3Chr.Chromosome 4 (mouse)1.00infobox
PER3DatabasesNCBI: entry; OMA: entry1.00infobox
PER3End7,845,177 bp1.00infobox
PER3End151,044,665 bp1.00infobox
PER3EnsemblENSG000000492461.00infobox

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