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Cryptochrome: History, Evolutionary history & Function

Cryptochromes (from the Greek κρυπτός χρώμα, "hidden colour") are a class of flavoproteins found in plants and animals that are sensitive to blue light. They are involved in the circadian rhythms and the sensing of magnetic fields in a number of species. The name cryptochrome was proposed as a portmanteau combining the chromatic nature of the…

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Cryptochrome topic overview

The analysis highlights History, Evolutionary history and Function as prominent areas in the source structure around Cryptochrome.

Related topics
132
Source areas
5
Connected nodes
137
Extracted relationships
104
Related term clusters
31
Bridge connections
137

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 54 topics
Function · 39 topics
Evolutionary history · 19 topics
Discovery · 10 topics
Structure · 10 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
HGNC
2384
Locus
Chr. 12 q23.3
NCBI gene
1407
OMIM
601933
PDB
5T5X

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Cryptochrome
3Magnetic fields · Drosophila · Mouse
3Chromophore · Pterin · 5,10-methenyltetrahydrofolic acid
3Anion · Radical (chemistry) · Spin (physics)
3Photosensitivity · Opsin · Action potential

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Evolutionary history

Structure

Function

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Cryptochrome connects Entity context

The extracted context around Cryptochrome shows recurring relationship patterns in the source. For example, Cryptochrome → Arabidopsis, C-terminal, Cry, CRY1, CRY2, Cryptochromes, Despite, Drosophila, Due, PER, SCN, Studies, T-DNA, The Drosophila, TIM, UV-induced DNA Another extracted example is Cryptochrome → Cry, CRY1, CRY2, DD, Drosophila, Drosophila-like, In Drosophila, LD, PER, Per1, Similarly, Studies, TIM. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cryptochrome

Top relations

related to history · 16
Cryptochrome → Arabidopsis, C-terminal, Cry, CRY1, CRY2, Cryptochromes, Despite, Drosophila, Due, PER, SCN, Studies, T-DNA, The Drosophila, TIM, UV-induced DNA
related to Circadian rhythm · 13
Cryptochrome → Cry, CRY1, CRY2, DD, Drosophila, Drosophila-like, In Drosophila, LD, PER, Per1, Similarly, Studies, TIM
related to Light capture · 13
Cryptochrome → Arabidopsis, ATP, C-terminal, C-terminus, COP1, Cryptochromes, Despite, Drosophila, FAD, FADH, HY5, MTHF, Past
related to Iris function · 12
Cryptochrome → CRY, CRY-mediated PMTRs, CRY1, CRY2, Howard, Isolated, Margiotta, PMTR, PMTRs, Research, Similarly, The PMTR
related to Magnetoreception · 11
Cryptochrome → Activation, Animal, Arabidopsis, Cryptochromes, Drosophila, Experimental, FADH-superoxide, Magnetic, Magnetoreception, Nevertheless, Radical
related to Discovery · 10
Cryptochrome → Although Charles Darwin, Arabidopsis, Comparative, Cry, DNA, Drosophila, FAD, HY4, Isoform, Reference
related to Structure · 8
Cryptochrome → C-terminal, CRY1, DNA, FAD, N-terminal, PHR, The PHR, The Ramachandran
related to Phototropism · 5
Cryptochrome → Arabidopsis, Arabidopsis CRY2, Cry2, Early Flowering, Unlike
related to Photomorphogenesis · 4
Cryptochrome → CRY1, CRY2, Cryptochromes, In Arabidopsis
Domains · 1
Cryptochrome → InterPro

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

light cry circadian cry1 cryptochromes gene proteins drosophila cry2 photolyase protein clock photoreceptor blue flavin transcription also genes levels role

Cryptochrome relationships Subject–Predicate–Object triples

TTTA extracted 104 structured relationships around Cryptochrome. Examples in this analysis include Cryptochrome → Domains → InterPro and Cryptochrome → HGNC → 2384. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CryptochromeDomainsInterPro1.00infobox
CryptochromeHGNC23841.00infobox
CryptochromeLocusChr. 12 q23.31.00infobox
CryptochromeNCBI gene14071.00infobox
CryptochromeOMIM6019331.00infobox
CryptochromePDB5T5X1.00infobox
CryptochromeRefSeqNP_0040661.00infobox
CryptochromeSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CryptochromeStructuresSwiss-model1.00infobox
CryptochromeSymbolCRY11.00infobox
CryptochromeUniProtQ165261.00infobox
ELONGATED HYPOCOTYL 5instance ofThe interaction inhibits COP1 activity and allows transcription factors0.80text

Related concept clusters Related term clusters

The concept neighborhoods around Cryptochrome bring nearby vocabulary together. In this analysis, examples include Proteins, Photolyase and Drosophila. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cryptochrome
    • Proteins
    • Photolyase
    • Drosophila
    • Protein
    • Genes
    • Clock
    • Light
    • Mammalian
    • Gene
    • Involved
    • Plant
    • Magnetic
  • cryptochrome
    • Proteins
    • Photolyase
    • Drosophila
    • Protein
    • Genes
    • Clock
    • Light
    • Mammalian
    • Gene
    • Involved
    • Plant
    • Magnetic
  • blue light
    • Light
    • Plants
    • Cry
    • Drosophila
    • Gene
    • Arabidopsis
    • Circadian
    • Cryptochrome
    • Photolyase
    • Cryptochromes
    • Protein
    • Levels
  • circadian rhythms
    • Rhythms
    • Role
    • Clock
    • Involved
    • Mammalian
    • Photoreceptor
    • Cry1
    • Mrna
    • Light
    • Plants
    • Also
    • Expression
  • gene expression
    • Mice
    • Photolyase
    • Plant
    • Light
    • Rhythms
    • Mammalian
    • Levels
    • Role
    • Photoreceptor
    • Drosophila
    • Per
    • Photomorphogenesis
  • clock
    • Per
    • Mammalian
    • Cry2
    • Transcription
    • Cryptochrome
    • Genes
    • Proteins
    • Cycle
    • Involved
    • Cry
    • Role
    • Light
  • depletion of cry1
    • Cry2
    • Expression
    • Levels
    • Mice
    • Dna
    • Genes
    • Role
    • Photoreceptor
    • Mrna
    • Rhythms
    • Mammalian
    • Proteins
  • circadian
    • Rhythms
    • Clock
    • Role
    • Involved
    • Mammalian
    • Photoreceptor
    • Cry1
    • Light
    • Also
    • Expression
    • Cry
    • Levels

Connections between topic areas Semantic bridges

For Cryptochrome, one of the stronger structural bridges in this analysis connects Cryptochrome with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Cryptochrome — Overview · splits 83 ⟂ 55
Cryptochrome — Function · splits 98 ⟂ 40
Cryptochrome — Evolutionary history · splits 118 ⟂ 20
Cryptochrome — Discovery · splits 127 ⟂ 11
Cryptochrome — Structure · splits 127 ⟂ 11

Map overview Semantic statistics

Cryptochrome

Nodes138
Edges137
Triples104
Avg. degree1.99
Density0.014493
Components1

Source & methodology

TTTA analyzes the structure around Cryptochrome to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Evolutionary history & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cryptochrome · EN edition · Analysis: TopicsToTalkAbout

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