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Cryptochrome: History, Evolutionary history & Function

Cryptochromes (from the Greek κρυπτός χρώμα, "hidden colour") are a class of flavoproteins found in plants and animals that are sensitive to blue light. They are involved in the circadian rhythms and the sensing of magnetic fields in a number of species. The name cryptochrome was proposed as a portmanteau combining the chromatic nature of the…

Language: English [EN]
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Cryptochrome topic overview

The analysis highlights History, Evolutionary history and Function as prominent areas in the source structure around Cryptochrome.

Related topics
140
Source areas
5
Connected nodes
145
Extracted relationships
155
Concept neighborhoods
31
Bridge connections
145

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 62 topics
Function · 39 topics
Evolutionary history · 19 topics
Discovery · 10 topics
Structure · 10 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
HGNC
2384
Locus
Chr. 12 q23.3
NCBI gene
1407
OMIM
601933
PDB
5T5X

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Evolutionary history

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cryptochrome connects Entity context

The extracted context around Cryptochrome shows recurring relationship patterns in the source. For example, Cryptochrome → Animated, Arabidopsis, Computational Biophysics Group, CryOverview, Department, Illinois, Magnetic Sensing, MassachusettsCryptochrome, Medicine Medical Subject Headings, MeSH, Monarch Butterflies Archived, Mouse Cryptochrome-1, National Library, Neurobiology, P97784, PDB, PDBe-KB, Protein Data Bank, Reppert, Steven Another extracted example is Cryptochrome → Arabidopsis, By, C-terminal, Cry, CRY1, CRY2, Cryptochromes, Despite, Drosophila, Due, In, PER, SCN, Studies, T-DNA, The, The Drosophila, These, TIM, UV-induced DNA. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cryptochrome

Top relations

related to External links · 26
Cryptochrome → Animated, Arabidopsis, Computational Biophysics Group, CryOverview, Department, Illinois, Magnetic Sensing, MassachusettsCryptochrome, Medicine Medical Subject Headings, MeSH, Monarch Butterflies Archived, Mouse Cryptochrome-1, National Library, Neurobiology, P97784, PDB, PDBe-KB, Protein Data Bank, Reppert, Steven
related to history · 21
Cryptochrome → Arabidopsis, By, C-terminal, Cry, CRY1, CRY2, Cryptochromes, Despite, Drosophila, Due, In, PER, SCN, Studies, T-DNA, The, The Drosophila, These, TIM, UV-induced DNA
related to Circadian rhythm · 17
Cryptochrome → Cry, CRY1, CRY2, DD, Drosophila, Drosophila-like, However, In, In Drosophila, LD, PER, Per1, Similarly, Some, Studies, These, TIM
related to Light capture · 17
Cryptochrome → Arabidopsis, ATP, Both, C-terminal, C-terminus, COP1, Cryptochromes, Despite, Drosophila, FAD, FADH, HY5, MTHF, Past, The, This, Under
related to Iris function · 13
Cryptochrome → CRY, CRY-mediated PMTRs, CRY1, CRY2, Howard, Isolated, Margiotta, PMTR, PMTRs, Research, Similarly, The, The PMTR
related to Discovery · 12
Cryptochrome → Although Charles Darwin, Arabidopsis, Comparative, Cry, DNA, Drosophila, FAD, However, HY4, In, Isoform, Reference
related to Magnetoreception · 12
Cryptochrome → Activation, Animal, Arabidopsis, Cryptochromes, Drosophila, Experimental, FADH-superoxide, Magnetic, Magnetoreception, Nevertheless, Radical, The
related to Structure · 11
Cryptochrome → All, C-terminal, CRY1, DNA, FAD, N-terminal, PHR, The, The PHR, The Ramachandran, These
related to Phototropism · 9
Cryptochrome → Arabidopsis, Arabidopsis CRY2, Cry2, Early Flowering, In, Their, This, To, Unlike
related to Photomorphogenesis · 5
Cryptochrome → CRY1, CRY2, Cryptochromes, In Arabidopsis, They

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

light cry circadian cry1 cryptochromes gene proteins drosophila cry2 photolyase protein clock photoreceptor blue flavin transcription also genes levels role

Cryptochrome relationships Subject–Predicate–Object triples

TTTA extracted 155 structured relationships around Cryptochrome. Examples in this analysis include Cryptochrome → Domains → InterPro and Cryptochrome → HGNC → 2384. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CryptochromeDomainsInterPro1.00infobox
CryptochromeHGNC23841.00infobox
CryptochromeLocusChr. 12 q23.31.00infobox
CryptochromeNCBI gene14071.00infobox
CryptochromeOMIM6019331.00infobox
CryptochromePDB5T5X1.00infobox
CryptochromeRefSeqNP_0040661.00infobox
CryptochromeSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CryptochromeStructuresSwiss-model1.00infobox
CryptochromeSymbolCRY11.00infobox
CryptochromeUniProtQ165261.00infobox
ELONGATED HYPOCOTYL 5instance ofThe interaction inhibits COP1 activity and allows transcription factors0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cryptochrome bring nearby vocabulary together. In this analysis, examples include Proteins, Photolyase and Drosophila. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cryptochrome
    • Proteins
    • Photolyase
    • Drosophila
    • Protein
    • Genes
    • Clock
    • Light
    • Mammalian
    • Gene
    • Involved
    • Plant
    • Magnetic
  • cryptochrome
    • Proteins
    • Photolyase
    • Drosophila
    • Protein
    • Genes
    • Clock
    • Light
    • Mammalian
    • Gene
    • Involved
    • Plant
    • Magnetic
  • blue light
    • Light
    • Plants
    • Cry
    • Drosophila
    • Gene
    • Arabidopsis
    • Circadian
    • Cryptochrome
    • Photolyase
    • However
    • Cryptochromes
    • Protein
  • circadian rhythms
    • Rhythms
    • Role
    • Clock
    • Involved
    • Mammalian
    • Photoreceptor
    • Cry1
    • Mrna
    • Light
    • Plants
    • Also
    • Expression
  • gene expression
    • Mice
    • Photolyase
    • Plant
    • Light
    • Rhythms
    • Mammalian
    • Levels
    • Role
    • Photoreceptor
    • Drosophila
    • Per
    • Photomorphogenesis
  • clock
    • Per
    • Mammalian
    • Cry2
    • Transcription
    • Cryptochrome
    • Genes
    • Proteins
    • Cycle
    • Involved
    • Cry
    • Role
    • Light
  • depletion of cry1
    • Cry2
    • Expression
    • Levels
    • Mice
    • Dna
    • Genes
    • Role
    • Photoreceptor
    • Mrna
    • Rhythms
    • Mammalian
    • Proteins
  • circadian
    • Rhythms
    • Clock
    • Role
    • Involved
    • Mammalian
    • Photoreceptor
    • Cry1
    • Light
    • Also
    • Expression
    • Cry
    • Levels

Connections between topic areas Semantic bridges

For Cryptochrome, one of the stronger structural bridges in this analysis connects Cryptochrome with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CryptochromeOverview · splits 83 ⟂ 63
CryptochromeFunction · splits 106 ⟂ 40
CryptochromeEvolutionary history · splits 126 ⟂ 20
CryptochromeDiscovery · splits 135 ⟂ 11
CryptochromeStructure · splits 135 ⟂ 11

Map overview Semantic statistics

Cryptochrome

Nodes146
Edges145
Triples155
Avg. degree1.99
Density0.013699
Components1

Source & methodology

TTTA analyzes the structure around Cryptochrome to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Evolutionary history & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cryptochrome · EN edition · Analysis: TopicsToTalkAbout

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