Pemoline, formerly sold under the brand name Cylert among others, is a stimulant medication which was used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It has since been discontinued in most countries due to rare but serious liver toxicity. The medication was taken by mouth.
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Pemoline topic overview
The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Pemoline.
Related topics
83
Source areas
10
Connected nodes
93
Extracted relationships
103
Related term clusters
24
Bridge connections
93
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Overview · 25 topics
Pharmacology · 18 topics
Chemistry · 8 topics
History · 8 topics
Medical uses · 7 topics
Side effects · 6 topics
Society and culture · 5 topics
Research · 3 topics
Interactions · 2 topics
Overdose · 1 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
3D model (JSmol)
Interactive image
AHFS/Drugs.com
Micromedex Detailed Consumer Information
ATC code
N06BA05 (WHO)
CAS Number
2152-34-3 N
ChEBI
CHEBI:7953 Y
ChEMBL
ChEMBL1177 Y
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Advanced semantic analysis
How Pemoline connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around Pemoline shows recurring relationship patterns in the source. For example, Pemoline → Abbott Laboratories, ADHD, Canada, Cases, Clinicians, December, Drug Administration, Drug Administration's MedWatch, FDA, FDA's, Japan, June, May, November, September, Serious, United Kingdom, United States, United States Food, Warnings Another extracted example is Pemoline → BANTooltip British Approved Name, Betanamin, Ceractiv, Cylert, Hyperilex, INNTooltip International Nonproprietary Name, Kethamed, Name, Ronyl, Stimul, Tamilan, Tradon, Tropocer, USANTooltip United States Adopted, Volital. Use these groups to spot repeated connection types before inspecting the individual relationships.
Pemoline
Top relations
related to history· 20
Pemoline → Abbott Laboratories, ADHD, Canada, Cases, Clinicians, December, Drug Administration, Drug Administration's MedWatch, FDA, FDA's, Japan, June, May, November, September, Serious, United Kingdom, United States, United States Food, Warnings
related to Names· 15
Pemoline → BANTooltip British Approved Name, Betanamin, Ceractiv, Cylert, Hyperilex, INNTooltip International Nonproprietary Name, Kethamed, Name, Ronyl, Stimul, Tamilan, Tradon, Tropocer, USANTooltip United States Adopted, Volital
related to Availability· 10
Pemoline → Argentina, Belgium, Canada, Germany, Japan, Luxembourg, Spain, Switzerland, United Kingdom, United States
related to Liver toxicity· 8
Pemoline → ADHD, Approximately, Canada, FDA, Japan, Rarely, Since, United States
related to Legal status· 6
Pemoline → Convention, DEA ACSCN, IV, Psychotropic Substances, Schedule IV Non-Narcotic, Stimulant
Legal status· 5
Pemoline → AU: S4 (Prescription only), BR: Class B1 (Psychoactive drugs), CA: Schedule IV, DE: Prescription only (Anlage III for higher doses), US: Schedule IV
related to Pharmacodynamics· 3
Pemoline → II, IV, Nonetheless
related to Pharmacokinetics· 3
Pemoline → Peak, Steady-state, Studies
3D model (JSmol)· 1
Pemoline → Interactive image
AHFS/Drugs.com· 1
Pemoline → Micromedex Detailed Consumer Information
Important terminology
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 103 structured relationships around Pemoline. Examples in this analysis include Pemoline → 3D model (JSmol) → Interactive image and Pemoline → AHFS/Drugs.com → Micromedex Detailed Consumer Information. The table shows each extracted connection, where it came from and its confidence.
Related term clusters group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around Pemoline bring nearby vocabulary together. In this analysis, examples include States, United and Liver. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Pemoline
States
United
Liver
Toxicity
Stimulant
Adhd
Effects
Treatment
Inhibitor
Reuptake
Dopamine
Iv
pemoline
States
United
Liver
Toxicity
Stimulant
Adhd
Effects
Treatment
Inhibitor
Reuptake
Dopamine
Iv
side effects
Side
Cardiovascular
Sympathomimetic
Stimulants
Stimulant
Activity
Inhibitor
Reuptake
Dopamine
Half-life
Hours
Pemoline
food and drug administration
Toxicity
Liver
States
United
Serious
Rare
Doses
Half-life
Hours
Inhibitor
Reuptake
Iv
liver toxicity
Toxicity
Cases
Drug
Serious
United
Rare
States
Pemoline
Narcolepsy
Used
Doses
Reported
liver damage
Toxicity
Cases
Drug
Serious
Rare
States
United
Pemoline
Narcolepsy
Used
Doses
Reported
liver transplantation
Toxicity
Cases
Drug
Serious
Rare
States
United
Pemoline
Narcolepsy
Used
Doses
Reported
liver failure
Toxicity
Cases
Drug
Serious
Rare
States
United
Pemoline
Narcolepsy
Used
Doses
Reported
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For Pemoline, one of the stronger structural bridges in this analysis connects Pemoline with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
Pemoline
Nodes94
Edges93
Triples103
Avg. degree1.98
Density0.021277
Components1
Source & methodology
TTTA analyzes the structure around Pemoline to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
