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PACS1: Clinical significance, Function & Interactions

Phosphofurin acidic cluster sorting protein 1, also known as PACS-1, is a protein that in humans is encoded by the PACS1 gene.

Language: English [EN]
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PACS1 topic overview

The analysis highlights Clinical significance, Function and Interactions as prominent areas in the source structure around PACS1.

Related topics
31
Source areas
4
Connected nodes
35
Extracted relationships
69
Concept neighborhoods
7
Bridge connections
35

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 23 topics
Function · 5 topics
Overview · 2 topics
Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PACS1, MRD17, phosphofurin acidic cluster sorting protein 1, SHMS
Band
11q13.1-q13.2 · 19|19 A
Bgee
minor salivary glands · granulocyte · stromal cell of endometrium · apex of heart · cerebellar hemisphere
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 19 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PACS1 connects Entity context

The extracted context around PACS1 shows recurring relationship patterns in the source. For example, PACS1 → apex of heart, cerebellar hemisphere, external carotid artery, genital tubercle, granulocyte, internal carotid artery, lacrimal gland, minor salivary glands, popliteal artery, right coronary artery, right hemisphere of cerebellum, right lung, seminiferous tubule, spermatid, spermatocyte, stromal cell of endometrium, tail of embryo, tibial arteries, zygote Another extracted example is PACS1 → COPI-coated vesicle, cytosol, Golgi apparatus, mitigation of host defenses by virus, protein binding, protein localization to Golgi apparatus, protein localization to plasma membrane, transmembrane transporter binding, viral process. Use these groups to spot repeated connection types before inspecting the individual relationships.

PACS1

Top relations

Bgee · 19
PACS1 → apex of heart, cerebellar hemisphere, external carotid artery, genital tubercle, granulocyte, internal carotid artery, lacrimal gland, minor salivary glands, popliteal artery, right coronary artery, right hemisphere of cerebellum, right lung, seminiferous tubule, spermatid, spermatocyte, stromal cell of endometrium, tail of embryo, tibial arteries, zygote
RNA expression pattern · 19
PACS1 → apex of heart, cerebellar hemisphere, external carotid artery, genital tubercle, granulocyte, internal carotid artery, lacrimal gland, minor salivary glands, popliteal artery, right coronary artery, right hemisphere of cerebellum, right lung, seminiferous tubule, spermatid, spermatocyte, stromal cell of endometrium, tail of embryo, tibial arteries, zygote
Gene ontology · 9
PACS1 → COPI-coated vesicle, cytosol, Golgi apparatus, mitigation of host defenses by virus, protein binding, protein localization to Golgi apparatus, protein localization to plasma membrane, transmembrane transporter binding, viral process
Band · 2
PACS1 → 11q13.1-q13.2, 19|19 A
Chr. · 2
PACS1 → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
PACS1 → 5,323,147 bp, 66,244,744 bp
Aliases · 1
PACS1 → PACS1, MRD17, phosphofurin acidic cluster sorting protein 1, SHMS
BioGPS · 1
PACS1 → More reference expression data
Databases · 1
PACS1 → NCBI: entry; OMA: entry
Ensembl · 1
PACS1 → ENSG00000175115

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp protein human gene chr band chromosome 11 reported mouse location localization phosphofurin acidic cluster sorting function role tgn identified

PACS1 relationships Subject–Predicate–Object triples

TTTA extracted 69 structured relationships around PACS1. Examples in this analysis include PACS1 → Aliases → PACS1, MRD17, phosphofurin acidic cluster sorting protein 1, SHMS and PACS1 → Band → 11q13.1-q13.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PACS1AliasesPACS1, MRD17, phosphofurin acidic cluster sorting protein 1, SHMS1.00infobox
PACS1Band11q13.1-q13.21.00infobox
PACS1Band19|19 A1.00infobox
PACS1Bgeeminor salivary glands1.00infobox
PACS1Bgeegranulocyte1.00infobox
PACS1Bgeestromal cell of endometrium1.00infobox
PACS1Bgeeapex of heart1.00infobox
PACS1Bgeecerebellar hemisphere1.00infobox
PACS1Bgeeright hemisphere of cerebellum1.00infobox
PACS1Bgeeright lung1.00infobox
PACS1Bgeeright coronary artery1.00infobox
PACS1Bgeepopliteal artery1.00infobox
PACS1Bgeetibial arteries1.00infobox
PACS1Bgeeseminiferous tubule1.00infobox
PACS1Bgeeinternal carotid artery1.00infobox
PACS1Bgeeexternal carotid artery1.00infobox
PACS1Bgeegenital tubercle1.00infobox
PACS1Bgeespermatid1.00infobox
PACS1Bgeetail of embryo1.00infobox
PACS1Bgeelacrimal gland1.00infobox
PACS1Bgeezygote1.00infobox
PACS1Bgeespermatocyte1.00infobox
PACS1BioGPSMore reference expression data1.00infobox
PACS1Chr.Chromosome 11 (human)1.00infobox
PACS1Chr.Chromosome 19 (mouse)1.00infobox
PACS1DatabasesNCBI: entry; OMA: entry1.00infobox
PACS1End66,244,744 bp1.00infobox
PACS1End5,323,147 bp1.00infobox
PACS1EnsemblENSG000001751151.00infobox
PACS1Entrez556901.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PACS1 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PACS1
    • Gene
    • Protein
    • External
    • Function
    • Phosphofurin
    • Sorting
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • Membrane
  • pacs1
    • Gene
    • Protein
    • External
    • Function
    • Phosphofurin
    • Sorting
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • Membrane
  • protein
    • Role
    • Tgn
    • Human
    • Binding
    • Cell
    • External
    • Function
    • Localization
    • Sorting
    • Location
    • Mouse
    • Chromosome
  • gene
    • Pacs1
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • Protein
    • 1-q13
    • End
    • External
    • Function
    • Pacs-1
  • function
    • External
    • Location
    • Chromosome
    • Membrane
    • Bp
    • Chr
    • Gene
    • Human
    • Pacs1
    • Protein
    • 1-q13
    • Binding
  • furin
    • Localization
    • Identified
    • Mouse
    • Role
    • Tgn
    • Pacs1
    • Protein
  • de novo mutation
    • Reported
    • Traits
    • Cases
    • Pacs1

Connections between topic areas Semantic bridges

For PACS1, one of the stronger structural bridges in this analysis connects PACS1 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PACS1Clinical significance · splits 12 ⟂ 24
PACS1Function · splits 30 ⟂ 6
PACS1Overview · splits 33 ⟂ 3

Map overview Semantic statistics

PACS1

Nodes36
Edges35
Triples69
Avg. degree1.94
Density0.055556
Components1

Source & methodology

TTTA analyzes the structure around PACS1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PACS1 · EN edition · Analysis: TopicsToTalkAbout

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