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P7C3 (pool 7, compound 3) is a drug related to latrepirdine (dimebon) which has neuroprotective and proneurogenic effects and may be potentially useful for the treatment of Alzheimer's disease and similar neurodegenerative disorders. The pharmacological effects of P7C3 in vitro resemble those of endogenous proneurogenic peptides such as fibroblast growth…
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compounds latrepirdine proneurogenic related effects similar activity times action nampt nad drug neuroprotective pharmacological endogenous peptides pharmacokinetic oral bioavailability p7c3-a20
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| P7C3 | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| P7C3 | CAS Number | 301353-96-8 | 1.00 | infobox |
| P7C3 | ChEMBL | ChEMBL2442630 N | 1.00 | infobox |
| P7C3 | ChemSpider | 2113543 N | 1.00 | infobox |
| P7C3 | CompTox Dashboard (EPA) | DTXSID70385472 | 1.00 | infobox |
| P7C3 | Formula | C21H18Br2N2O | 1.00 | infobox |
| P7C3 | Molar mass | 474.196 g·mol−1 | 1.00 | infobox |
| P7C3 | PubChem CID | 2836187 | 1.00 | infobox |
| P7C3 | UNII | 77ZWJ3QXR9 | 1.00 | infobox |
| fibroblast growth factor 1 | instance of | The pharmacological effects of P7C3 in vitro resemble those of endogenous proneurogenic peptides | 0.80 | text |
| the more potent fluorinated analogue P7C3-A20 which is up to ten times stronger again | instance of | but several other related compounds showed similar activity | 0.80 | text |
| and the methoxy analogue P7C3-OMe | instance of | but several other related compounds showed similar activity | 0.80 | text |
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