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GPR37: Regions, Interactions & Overview

Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene. GPR37 is primarily found in the central nervous system (CNS), with significant expression observed in various CNS regions including the amygdala, basal ganglia (caudate, putamen, and nucleus accumbens), substantia nigra, hippocampus, frontal cortex, and…

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GPR37 topic overview

The analysis highlights Regions, Interactions and Overview as prominent areas in the source structure around GPR37.

Related topics
27
Source areas
2
Connected nodes
29
Extracted relationships
96
Related term clusters
16
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 14 topics
Overview · 13 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GPR37, EDNRBL, PAELR, hET(B)R-LP, G protein-coupled receptor 37
Band
7q31.33 · 6 A3.1|6 11.65 cM
Bgee
secondary oocyte · inferior ganglion of vagus nerve · optic nerve · middle frontal gyrus · subthalamic nucleus
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How GPR37 connects Entity context

The extracted context around GPR37 shows recurring relationship patterns in the source. For example, GPR37 → adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, dopamine biosynthetic process, endoplasmic reticulum, endoplasmic reticulum membrane, G protein-coupled peptide receptor activity, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, heat shock protein binding, Hsp70 protein binding, integral component of membrane, integral component of plasma membrane, locomotion involved in locomotory behavior, membrane, negative regulation of hydrogen peroxide-induced cell death, peptide binding, plasma membrane, positive regulation of dopamine metabolic process, positive regulation of MAPK cascade, prosaposin receptor activity, protein binding Another extracted example is GPR37 → anterior horn of spinal cord, deep cerebellar nuclei, external globus pallidus, globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, lateral geniculate nucleus, lumbar subsegment of spinal cord, medial geniculate nucleus, medulla oblongata, middle frontal gyrus, optic nerve, pontine nuclei, secondary oocyte, subthalamic nucleus, superior vestibular nucleus, utricle, ventral tegmental area, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.

GPR37

Top relations

Gene ontology · 25
GPR37 → adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, dopamine biosynthetic process, endoplasmic reticulum, endoplasmic reticulum membrane, G protein-coupled peptide receptor activity, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, heat shock protein binding, Hsp70 protein binding, integral component of membrane, integral component of plasma membrane, locomotion involved in locomotory behavior, membrane, negative regulation of hydrogen peroxide-induced cell death, peptide binding, plasma membrane, positive regulation of dopamine metabolic process, positive regulation of MAPK cascade, prosaposin receptor activity, protein binding
Bgee · 19
GPR37 → anterior horn of spinal cord, deep cerebellar nuclei, external globus pallidus, globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, lateral geniculate nucleus, lumbar subsegment of spinal cord, medial geniculate nucleus, medulla oblongata, middle frontal gyrus, optic nerve, pontine nuclei, secondary oocyte, subthalamic nucleus, superior vestibular nucleus, utricle, ventral tegmental area, vestibular sensory epithelium
RNA expression pattern · 19
GPR37 → anterior horn of spinal cord, deep cerebellar nuclei, external globus pallidus, globus pallidus, inferior ganglion of vagus nerve, inferior olivary nucleus, lateral geniculate nucleus, lumbar subsegment of spinal cord, medial geniculate nucleus, medulla oblongata, middle frontal gyrus, optic nerve, pontine nuclei, secondary oocyte, subthalamic nucleus, superior vestibular nucleus, utricle, ventral tegmental area, vestibular sensory epithelium
related to Interactions · 8
GPR37 → Furthermore, GnRH, GPR37-deficient, HEK293, HSPA1A, Lipopolysaccharide-induced, OECs, Parkin
Band · 2
GPR37 → 6 A3.1|6 11.65 cM, 7q31.33
Chr. · 2
GPR37 → Chromosome 6 (mouse), Chromosome 7 (human)
End · 2
GPR37 → 124,765,792 bp, 25,690,728 bp
Aliases · 1
GPR37 → GPR37, EDNRBL, PAELR, hET(B)R-LP, G protein-coupled receptor 37
BioGPS · 1
GPR37 → More reference expression data
Databases · 1
GPR37 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp chr human band receptor gene chromosome location protein mouse 37 expression nucleus frontal spinal cord found protein-coupled external 765

GPR37 relationships Subject–Predicate–Object triples

TTTA extracted 96 structured relationships around GPR37. Examples in this analysis include GPR37 → Aliases → GPR37, EDNRBL, PAELR, hET(B)R-LP, G protein-coupled receptor 37 and GPR37 → Band → 7q31.33. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GPR37AliasesGPR37, EDNRBL, PAELR, hET(B)R-LP, G protein-coupled receptor 371.00infobox
GPR37Band7q31.331.00infobox
GPR37Band6 A3.1|6 11.65 cM1.00infobox
GPR37Bgeesecondary oocyte1.00infobox
GPR37Bgeeinferior ganglion of vagus nerve1.00infobox
GPR37Bgeeoptic nerve1.00infobox
GPR37Bgeemiddle frontal gyrus1.00infobox
GPR37Bgeesubthalamic nucleus1.00infobox
GPR37Bgeemedulla oblongata1.00infobox
GPR37Bgeeventral tegmental area1.00infobox
GPR37Bgeesuperior vestibular nucleus1.00infobox
GPR37Bgeeexternal globus pallidus1.00infobox
GPR37Bgeeinferior olivary nucleus1.00infobox
GPR37Bgeedeep cerebellar nuclei1.00infobox
GPR37Bgeelumbar subsegment of spinal cord1.00infobox
GPR37Bgeeglobus pallidus1.00infobox
GPR37Bgeelateral geniculate nucleus1.00infobox
GPR37Bgeeutricle1.00infobox
GPR37Bgeevestibular sensory epithelium1.00infobox
GPR37Bgeepontine nuclei1.00infobox
GPR37Bgeemedial geniculate nucleus1.00infobox
GPR37Bgeeanterior horn of spinal cord1.00infobox
GPR37BioGPSMore reference expression data1.00infobox
GPR37Chr.Chromosome 7 (human)1.00infobox
GPR37Chr.Chromosome 6 (mouse)1.00infobox
GPR37DatabasesNCBI: entry; OMA: entry1.00infobox
GPR37End124,765,792 bp1.00infobox
GPR37End25,690,728 bp1.00infobox
GPR37EnsemblENSG000001707751.00infobox
GPR37Entrez28611.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around GPR37 bring nearby vocabulary together. In this analysis, examples include Receptor, Gene and Cell. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GPR37
    • Receptor
    • Gene
    • Cell
    • Cord
    • Expressed
    • Expression
    • External
    • Frontal
    • Interactions
    • Nucleus
    • Prosaposin
    • Protein
  • gpr37
    • Receptor
    • Gene
    • Cell
    • Cord
    • Expressed
    • Expression
    • External
    • Frontal
    • Interactions
    • Nucleus
    • Prosaposin
    • Protein
  • protein
    • Gene
    • Ligase
    • Receptor
    • A3
    • Cell
    • Cord
    • End
    • Expressed
    • Expression
    • External
    • Frontal
    • Mouse
  • gene
    • Location
    • Chromosome
    • Human
    • A3
    • Bp
    • Chr
    • End
    • External
    • Mouse
    • Protein
    • Protein-coupled
    • Receptor
  • frontal cortex
    • Cord
    • Nucleus
    • Spinal
    • Hippocampus
    • Ligase
    • Putamen
    • A3
    • Cell
    • End
    • Expressed
    • External
    • Mouse
  • spinal cord
    • Cord
    • Expression
    • Frontal
    • Nucleus
    • Spinal
    • Amygdala
    • Caudate
    • Hippocampus
    • Ligase
    • Putamen
    • A3
    • Cell
  • primary cell cultures
    • Expressed
    • Ligase
    • Cord
    • End
    • Expression
    • External
    • Frontal
    • Interactions
    • Mouse
    • Nucleus
    • Prosaposin
    • Protein
  • nucleus accumbens
    • Spinal
    • Hippocampus
    • Ligase
    • Putamen
    • A3
    • Cell
    • End
    • Expressed
    • External
    • Mouse
    • Prosaposin
    • Protein

Connections between topic areas Semantic bridges

For GPR37, one of the stronger structural bridges in this analysis connects GPR37 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GPR37 — Interactions · splits 15 ⟂ 15
GPR37 — Overview · splits 16 ⟂ 14

Map overview Semantic statistics

GPR37

Nodes30
Edges29
Triples96
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around GPR37 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GPR37 · EN edition · Analysis: TopicsToTalkAbout

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