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GPRC6A: Clinical significance & Overview

G protein-coupled receptor family C group 6 member A (GPRC6A) is a protein that in humans is encoded by the GPRC6A gene. This protein functions as a receptor of L-α-amino acids, cations (e.g., calcium), osteocalcin, and steroids. It is a membrane androgen receptor.

Language: English [EN]
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GPRC6A topic overview

The analysis highlights Clinical significance and Overview as prominent areas in the source structure around GPRC6A.

Related topics
10
Source areas
2
Connected nodes
12
Extracted relationships
70
Concept neighborhoods
11
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 8 topics
Clinical significance · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A
Band
6q22.1 · 10|10 B3
Bgee
testicle · gonad · salivary gland · minor salivary glands · islet of Langerhans
BioGPS
n/a
Chr.
Chromosome 6 (human) · Chromosome 10 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GPRC6A connects Entity context

The extracted context around GPRC6A shows recurring relationship patterns in the source. For example, GPRC6A → embryo, gonad, human kidney, islet of Langerhans, left adrenal gland, left lung lobe, minor salivary glands, muscle of thigh, right adrenal cortex, right adrenal gland, right lung lobe, salivary gland, testicle Another extracted example is GPRC6A → calcium-mediated signaling, cell surface, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, membrane, plasma membrane, response to amino acid, signal transducer activity, signal transduction, signaling receptor activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

GPRC6A

Top relations

Bgee · 13
GPRC6A → embryo, gonad, human kidney, islet of Langerhans, left adrenal gland, left lung lobe, minor salivary glands, muscle of thigh, right adrenal cortex, right adrenal gland, right lung lobe, salivary gland, testicle
Gene ontology · 13
GPRC6A → calcium-mediated signaling, cell surface, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, membrane, plasma membrane, response to amino acid, signal transducer activity, signal transduction, signaling receptor activity
RNA expression pattern · 13
GPRC6A → embryo, gonad, human kidney, islet of Langerhans, left adrenal gland, left lung lobe, minor salivary glands, muscle of thigh, right adrenal cortex, right adrenal gland, right lung lobe, salivary gland, testicle
related to External links · 11
GPRC6A → Basic, Calcium-Sensing Receptors, Clinical Pharmacology, GPRC6, International Union, Ion Channels, IUPHAR Database, Medicine Medical Subject Headings, MeSH, National Library, Receptors
Band · 2
GPRC6A → 10|10 B3, 6q22.1
Chr. · 2
GPRC6A → Chromosome 10 (mouse), Chromosome 6 (human)
End · 2
GPRC6A → 116,829,083 bp, 51,507,557 bp
Aliases · 1
GPRC6A → GPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A
BioGPS · 1
GPRC6A → n/a
Databases · 1
GPRC6A → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor bp human chr band protein gene chromosome protein-coupled location membrane mouse group member external 829 083 end 116 10

GPRC6A relationships Subject–Predicate–Object triples

TTTA extracted 70 structured relationships around GPRC6A. Examples in this analysis include GPRC6A → Aliases → GPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A and GPRC6A → Band → 6q22.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GPRC6AAliasesGPRC6A, GPCR, bA86F4.3, G protein-coupled receptor class C group 6 member A1.00infobox
GPRC6ABand6q22.11.00infobox
GPRC6ABand10|10 B31.00infobox
GPRC6ABgeetesticle1.00infobox
GPRC6ABgeegonad1.00infobox
GPRC6ABgeesalivary gland1.00infobox
GPRC6ABgeeminor salivary glands1.00infobox
GPRC6ABgeeislet of Langerhans1.00infobox
GPRC6ABgeehuman kidney1.00infobox
GPRC6ABgeeright adrenal gland1.00infobox
GPRC6ABgeeright adrenal cortex1.00infobox
GPRC6ABgeemuscle of thigh1.00infobox
GPRC6ABgeeleft adrenal gland1.00infobox
GPRC6ABgeeembryo1.00infobox
GPRC6ABgeeleft lung lobe1.00infobox
GPRC6ABgeeright lung lobe1.00infobox
GPRC6ABioGPSn/a1.00infobox
GPRC6AChr.Chromosome 6 (human)1.00infobox
GPRC6AChr.Chromosome 10 (mouse)1.00infobox
GPRC6ADatabasesNCBI: entry; OMA: entry1.00infobox
GPRC6AEnd116,829,083 bp1.00infobox
GPRC6AEnd51,507,557 bp1.00infobox
GPRC6AEnsemblENSG000001736121.00infobox
GPRC6AEntrez2225451.00infobox
GPRC6AExternal IDsOMIM: 613572; MGI: 2429498; GeneCards: GPRC6A1.00infobox
GPRC6AGene location (Human)Gene location (Human)Chr.Chromosome 6 (human)Band6q22.1Start116,792,085 bpEnd116,829,083 bp1.00infobox
GPRC6AGene location (Mouse)Gene location (Mouse)Chr.Chromosome 10 (mouse)Band10|10 B3Start51,490,919 bpEnd51,507,557 bp1.00infobox
GPRC6AGene ontologyG protein-coupled receptor activity1.00infobox
GPRC6AGene ontologysignal transducer activity1.00infobox
GPRC6AGene ontologysignaling receptor activity1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GPRC6A bring nearby vocabulary together. In this analysis, examples include Protein-coupled, Gene and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GPRC6A
    • Protein-coupled
    • Gene
    • Protein
    • Also
    • Group
    • Human
    • Member
    • Receptor
    • Location
    • Chromosome
    • Bp
    • Chr
  • gprc6a
    • Protein-coupled
    • Gene
    • Protein
    • Also
    • Group
    • Human
    • Member
    • Receptor
    • Location
    • Chromosome
    • Bp
    • Chr
  • protein
    • Receptor
    • Protein-coupled
    • Gene
    • Human
    • Acids
    • Calcium
    • Cations
    • Cell
    • Encoded
    • Functions
    • Humans
    • L-α-amino
  • gene
    • Location
    • Protein-coupled
    • Chromosome
    • Gprc6a
    • Also
    • Bp
    • Chr
    • End
    • Group
    • Human
    • Member
    • Mouse
  • membrane androgen receptor
    • Cell
    • Membrane
    • Also
    • Receptor
    • End
    • Location
    • Mouse
    • Chromosome
    • Bp
    • Chr
    • Human
    • Protein-coupled
  • clinical significance
    • External
    • See
    • Also
    • Clinical
    • Group
    • Member
    • Significance
    • Location
    • Protein-coupled
    • Chromosome
    • Gene
    • Gprc6a
  • amino acids
    • Calcium
    • Cations
    • Functions
    • L-α-amino
    • Osteocalcin
    • Steroids
    • Protein
    • Receptor
  • steroids
    • Acids
    • Calcium
    • Cations
    • Functions
    • L-α-amino
    • Osteocalcin
    • Protein
    • Receptor

Connections between topic areas Semantic bridges

For GPRC6A, one of the stronger structural bridges in this analysis connects GPRC6A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GPRC6A — Overview · splits 4 ⟂ 9
GPRC6A — Clinical significance · splits 10 ⟂ 3

Map overview Semantic statistics

GPRC6A

Nodes13
Edges12
Triples70
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around GPRC6A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GPRC6A · EN edition · Analysis: TopicsToTalkAbout

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