TFAM

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Explore the main themes, entities and connections around TFAM. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Mitochondrial Transcription factor Embryonic development Kearns–Sayre syndrome High-mobility group

5 related topics

Interactions

Interact TFB1M TFB2M

3 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, transcription factor A, mitochondrial, MTDPS15
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3FGH, 3TMM, 3TQ6, 4NNU, 4NOD
Band: 10q21.1 · 10 B5.3|10 36.83 cM
Bgee: right testis · left testis · secondary oocyte · Achilles tendon · ventricular zone
BioGPS: More reference expression data
Chr.: Chromosome 10 (human) · Chromosome 10 (mouse)

Topics to explore

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Overview

Function

Interactions

Interact Protein–protein interaction
TFB1M
TFB2M

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes14

Edges13

Triples101

Avg. degree1.86

Density0.142857

Components1

How this topic connects Entity context

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TFAM

Top relations

Gene ontology · 29

TFAM → chromatin binding, cytosol, DNA binding, DNA binding, bending, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-dependent DNA replication, heat shock protein binding, mitochondrial matrix, mitochondrial nucleoid, mitochondrial promoter sequence-specific DNA binding, mitochondrial respiratory chain complex assembly, mitochondrial transcription, mitochondrion, mitochondrion organization, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, protein-containing complex

Bgee · 19

TFAM → abdominal wall, Achilles tendon, atrioventricular valve, embryo, endocardial cushion, epiblast, ganglionic eminence, germinal epithelium, gonad, left testis, migratory enteric neural crest cell, monocyte, mucosa of sigmoid colon, muscle of thigh, right testis, secondary oocyte, somite, triceps brachii muscle, ventricular zone

RNA expression pattern · 19

related to Function · 8

TFAM → Abf2, DNA, DNA-binding, High-mobility, Kearns, Sayre, Studies, This

Band · 2

TFAM → 10 B5.3|10 36.83 cM, 10q21.1

Chr. · 2

TFAM → Chromosome 10 (human), Chromosome 10 (mouse)

End · 2

TFAM → 58,399,220 bp, 71,074,110 bp

related to Interactions · 2

TFAM → TFB1M, TFB2M

Aliases · 1

TFAM → TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, transcription factor A, mitochondrial, MTDPS15

Available structures · 1

TFAM → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3FGH, 3TMM, 3TQ6, 4NNU, 4NOD

Important terminology Word statistics

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Important terminology

mitochondrial gene transcription bp chr human band factor chromosome 10 protein mouse location genome bending mttfa function external pdb uniprot

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
TFAM	Aliases	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, transcription factor A, mitochondrial, MTDPS15	1.00	infobox
TFAM	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3FGH, 3TMM, 3TQ6, 4NNU, 4NOD	1.00	infobox
TFAM	Band	10q21.1	1.00	infobox
TFAM	Band	10 B5.3\|10 36.83 cM	1.00	infobox
TFAM	Bgee	right testis	1.00	infobox
TFAM	Bgee	left testis	1.00	infobox
TFAM	Bgee	secondary oocyte	1.00	infobox
TFAM	Bgee	Achilles tendon	1.00	infobox
TFAM	Bgee	ventricular zone	1.00	infobox
TFAM	Bgee	monocyte	1.00	infobox
TFAM	Bgee	germinal epithelium	1.00	infobox
TFAM	Bgee	ganglionic eminence	1.00	infobox
TFAM	Bgee	mucosa of sigmoid colon	1.00	infobox
TFAM	Bgee	gonad	1.00	infobox
TFAM	Bgee	endocardial cushion	1.00	infobox
TFAM	Bgee	atrioventricular valve	1.00	infobox
TFAM	Bgee	abdominal wall	1.00	infobox
TFAM	Bgee	embryo	1.00	infobox
TFAM	Bgee	somite	1.00	infobox
TFAM	Bgee	migratory enteric neural crest cell	1.00	infobox
TFAM	Bgee	epiblast	1.00	infobox
TFAM	Bgee	muscle of thigh	1.00	infobox
TFAM	Bgee	triceps brachii muscle	1.00	infobox
TFAM	BioGPS	More reference expression data	1.00	infobox
TFAM	Chr.	Chromosome 10 (human)	1.00	infobox
TFAM	Chr.	Chromosome 10 (mouse)	1.00	infobox
TFAM	Databases	NCBI: entry; OMA: entry	1.00	infobox
TFAM	End	58,399,220 bp	1.00	infobox
TFAM	End	71,074,110 bp	1.00	infobox
TFAM	Ensembl	ENSG00000108064	1.00	infobox

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Min side: 3