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Mitochondrial transcription factor A, abbreviated as TFAM or mtTFA, is a protein that in humans is encoded by the TFAM gene.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around TFAM.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around TFAM shows recurring relationship patterns in the source. For example, TFAM → chromatin binding, cytosol, DNA binding, DNA binding, bending, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-dependent DNA replication, heat shock protein binding, mitochondrial matrix, mitochondrial nucleoid, mitochondrial promoter sequence-specific DNA binding, mitochondrial respiratory chain complex assembly, mitochondrial transcription, mitochondrion, mitochondrion organization, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, protein-containing complex Another extracted example is TFAM → abdominal wall, Achilles tendon, atrioventricular valve, embryo, endocardial cushion, epiblast, ganglionic eminence, germinal epithelium, gonad, left testis, migratory enteric neural crest cell, monocyte, mucosa of sigmoid colon, muscle of thigh, right testis, secondary oocyte, somite, triceps brachii muscle, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
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mitochondrial gene transcription bp chr human band factor chromosome 10 protein mouse location genome bending mttfa function external pdb uniprot
TTTA extracted 100 structured relationships around TFAM. Examples in this analysis include TFAM → Aliases → TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, transcription factor A, mitochondrial, MTDPS15 and TFAM → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3FGH, 3TMM, 3TQ6, 4NNU, 4NOD. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TFAM | Aliases | TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, transcription factor A, mitochondrial, MTDPS15 | 1.00 | infobox |
| TFAM | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3FGH, 3TMM, 3TQ6, 4NNU, 4NOD | 1.00 | infobox |
| TFAM | Band | 10q21.1 | 1.00 | infobox |
| TFAM | Band | 10 B5.3|10 36.83 cM | 1.00 | infobox |
| TFAM | Bgee | right testis | 1.00 | infobox |
| TFAM | Bgee | left testis | 1.00 | infobox |
| TFAM | Bgee | secondary oocyte | 1.00 | infobox |
| TFAM | Bgee | Achilles tendon | 1.00 | infobox |
| TFAM | Bgee | ventricular zone | 1.00 | infobox |
| TFAM | Bgee | monocyte | 1.00 | infobox |
| TFAM | Bgee | germinal epithelium | 1.00 | infobox |
| TFAM | Bgee | ganglionic eminence | 1.00 | infobox |
| TFAM | Bgee | mucosa of sigmoid colon | 1.00 | infobox |
| TFAM | Bgee | gonad | 1.00 | infobox |
| TFAM | Bgee | endocardial cushion | 1.00 | infobox |
| TFAM | Bgee | atrioventricular valve | 1.00 | infobox |
| TFAM | Bgee | abdominal wall | 1.00 | infobox |
| TFAM | Bgee | embryo | 1.00 | infobox |
| TFAM | Bgee | somite | 1.00 | infobox |
| TFAM | Bgee | migratory enteric neural crest cell | 1.00 | infobox |
| TFAM | Bgee | epiblast | 1.00 | infobox |
| TFAM | Bgee | muscle of thigh | 1.00 | infobox |
| TFAM | Bgee | triceps brachii muscle | 1.00 | infobox |
| TFAM | BioGPS | More reference expression data | 1.00 | infobox |
| TFAM | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| TFAM | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| TFAM | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TFAM | End | 58,399,220 bp | 1.00 | infobox |
| TFAM | End | 71,074,110 bp | 1.00 | infobox |
| TFAM | Ensembl | ENSG00000108064 | 1.00 | infobox |
The concept neighborhoods around TFAM bring nearby vocabulary together. In this analysis, examples include Transcription, Protein and Genome. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TFAM, one of the stronger structural bridges in this analysis connects TFAM with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TFAM to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TFAM · EN edition · Analysis: TopicsToTalkAbout
