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NADPH oxidase 2 (Nox2), also known as cytochrome b(558) subunit beta or Cytochrome b-245 heavy chain, is a protein that in humans is encoded by the NOX2 gene (also called CYBB gene). The protein is a superoxide generating enzyme which forms reactive oxygen species (ROS).
Measurement, Function & Clinical significance
Explore the main themes, entities and connections around NOX2. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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nadph gene cybb oxidase human protein bp chain chr band cytochrome beta b-245 ros chromosome complex location role due also
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| NOX2 | Aliases | CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX, cytochrome b-245 beta chain, CGDX | 1.00 | infobox |
| NOX2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1F | 1.00 | infobox |
| NOX2 | Band | Xp21.1-p11.4 | 1.00 | infobox |
| NOX2 | Band | X|X A1.1 | 1.00 | infobox |
| NOX2 | Bgee | monocyte | 1.00 | infobox |
| NOX2 | Bgee | granulocyte | 1.00 | infobox |
| NOX2 | Bgee | bone marrow | 1.00 | infobox |
| NOX2 | Bgee | bone marrow cell | 1.00 | infobox |
| NOX2 | Bgee | synovial joint | 1.00 | infobox |
| NOX2 | Bgee | blood | 1.00 | infobox |
| NOX2 | Bgee | trabecular bone | 1.00 | infobox |
| NOX2 | Bgee | appendix | 1.00 | infobox |
| NOX2 | Bgee | lymph node | 1.00 | infobox |
| NOX2 | Bgee | decidua | 1.00 | infobox |
| NOX2 | Bgee | stroma of bone marrow | 1.00 | infobox |
| NOX2 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| NOX2 | Bgee | right lung lobe | 1.00 | infobox |
| NOX2 | Bgee | spleen | 1.00 | infobox |
| NOX2 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| NOX2 | Bgee | tibiofemoral joint | 1.00 | infobox |
| NOX2 | Bgee | calvaria | 1.00 | infobox |
| NOX2 | Bgee | ankle | 1.00 | infobox |
| NOX2 | BioGPS | More reference expression data | 1.00 | infobox |
| NOX2 | Chr. | X chromosome (human) | 1.00 | infobox |
| NOX2 | Chr. | X chromosome (mouse) | 1.00 | infobox |
| NOX2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| NOX2 | End | 37,813,461 bp | 1.00 | infobox |
| NOX2 | End | 9,354,010 bp | 1.00 | infobox |
| NOX2 | Ensembl | ENSG00000165168 | 1.00 | infobox |
| NOX2 | Entrez | 1536 | 1.00 | infobox |
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