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Nilutamide: History, Community, Culture & Applications

Nilutamide, sold under the brand names Nilandron and Anandron, is a nonsteroidal antiandrogen (NSAA) which is used in the treatment of prostate cancer. It has also been studied as a component of feminizing hormone therapy for transgender women and to treat acne and seborrhea in women. It is taken by mouth.

Language: English [EN]
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Nilutamide topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Nilutamide.

Related topics
156
Source areas
8
Connected nodes
164
Extracted relationships
111
Concept neighborhoods
27
Bridge connections
164

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 59 topics
Side effects · 33 topics
Medical uses · 28 topics
Society and culture · 26 topics
Pharmacology · 5 topics
History · 3 topics
Chemistry · 1 topics
Research · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L02BB02 (WHO)
Bioavailability
Good
CAS Number
63612-50-0 Y
ChEBI
CHEBI:7573 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Pharmacology

Chemistry

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Nilutamide connects Entity context

The extracted context around Nilutamide shows recurring relationship patterns in the source. For example, Nilutamide → Argentina, Australia, Belgium, Brazil, Canada, Croatia, Czech Republic, Egypt, Europe, Finland, France, In Europe, Latin America, Lebanon, Mexico, Netherlands, Norway, Poland, Portugal, Serbia Another extracted example is Nilutamide → Also, Asian, General, Japanese, NSAAs, Relative, The, There. Use these groups to spot repeated connection types before inspecting the individual relationships.

Nilutamide

Top relations

related to Availability · 24
Nilutamide → Argentina, Australia, Belgium, Brazil, Canada, Croatia, Czech Republic, Egypt, Europe, Finland, France, In Europe, Latin America, Lebanon, Mexico, Netherlands, Norway, Poland, Portugal, Serbia
has effect · 8
Nilutamide → Also, Asian, General, Japanese, NSAAs, Relative, The, There
related to Brand names · 7
Nilutamide → Anandron, Australia, Canada, Europe, Latin America, Nilandron, United States
related to Generic names · 5
Nilutamide → BANTooltip British Approved Name, DCFTooltip Dénomination Commune Française, INNTooltip International Nonproprietary Name, Name, USANTooltip United States Adopted
related to history · 5
Nilutamide → France, It, NSAA, Roussel, United States
related to Pharmacokinetics · 4
Nilutamide → CYP2C19, It, Steady, Virtually
related to Prostate cancer · 3
Nilutamide → GnRH, It, Only
related to Transgender hormone therapy · 3
Nilutamide → In, It, Signs
3D model (JSmol) · 1
Nilutamide → Interactive image
AHFS/Drugs.com · 1
Nilutamide → Monograph

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

prostate cancer flutamide testosterone bicalutamide effects levels treatment liver monotherapy hormone therapy available used transgender side antiandrogen drug feminization enzymes

Nilutamide relationships Subject–Predicate–Object triples

TTTA extracted 111 structured relationships around Nilutamide. Examples in this analysis include Nilutamide → 3D model (JSmol) → Interactive image and Nilutamide → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Nilutamide3D model (JSmol)Interactive image1.00infobox
NilutamideAHFS/Drugs.comMonograph1.00infobox
NilutamideATC codeL02BB02 (WHO)1.00infobox
NilutamideBioavailabilityGood1.00infobox
NilutamideCAS Number63612-50-0 Y1.00infobox
NilutamideChEBICHEBI:7573 Y1.00infobox
NilutamideChEMBLChEMBL1274 Y1.00infobox
NilutamideChemSpider4337 Y1.00infobox
NilutamideCompTox Dashboard (EPA)DTXSID30341651.00infobox
NilutamideDrug classNonsteroidal antiandrogen1.00infobox
NilutamideDrugBankDB00665 Y1.00infobox
NilutamideECHA InfoCard100.153.2681.00infobox
NilutamideElimination half-lifeMean: 56 hours (~2 days) Range: 23–87 hours1.00infobox
NilutamideExcretionUrine: 62% Feces: <10%1.00infobox
NilutamideFormulaC12H10F3N3O41.00infobox
NilutamideIUPHAR/BPS28641.00infobox
NilutamideKEGGD00965 Y1.00infobox
NilutamideLegal statusIn general: ℞ (Prescription only)1.00infobox
NilutamideMedlinePlusa6970441.00infobox
NilutamideMelting point149 °C (300 °F)1.00infobox
NilutamideMetabolismLiver (CYP2C19, FMOTooltip flavin-containing monooxygenase)1.00infobox
NilutamideMetabolitesAt least 5, some active1.00infobox
NilutamideMolar mass317.224 g·mol−11.00infobox
NilutamideOther namesRU-239081.00infobox
NilutamidePronunciationnye-LOO-tah-mide1.00infobox
NilutamideProtein binding80–84%1.00infobox
NilutamidePubChem CID44931.00infobox
NilutamideRoutes of administrationBy mouth1.00infobox
NilutamideTrade namesNilandron, Anandron1.00infobox
NilutamideUNII51G6I8B9021.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Nilutamide bring nearby vocabulary together. In this analysis, examples include Cancer, Prostate and Testosterone. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Nilutamide
    • Cancer
    • Prostate
    • Testosterone
    • Treatment
    • Flutamide
    • Bicalutamide
    • Levels
    • Effects
    • Including
    • Monotherapy
    • Therapy
    • Androgen
  • nilutamide
    • Cancer
    • Prostate
    • Testosterone
    • Treatment
    • Flutamide
    • Bicalutamide
    • Levels
    • Effects
    • Including
    • Monotherapy
    • Therapy
    • Androgen
  • nonsteroidal antiandrogen
    • Names
    • Cancer
    • Prostate
    • Transgender
    • Used
    • Treatment
    • Androgen
    • Feminization
    • Like
    • Side
    • Available
    • Drug
  • feminizing hormone therapy
    • Transgender
    • Therapy
    • Studied
    • Testosterone
    • Women
    • Used
    • Weeks
    • Effects
    • Levels
    • Names
    • Side
    • Use
  • side effects
    • Side
    • Associated
    • Men
    • Breast
    • Used
    • Therapy
    • Testosterone
    • Names
    • Prostate
    • Use
    • Available
    • Decreased
  • prostate cancer
    • Prostate
    • Treatment
    • Monotherapy
    • Men
    • Used
    • Names
    • Nilutamide
    • Androgen
    • Studied
    • Effects
    • Therapy
    • Side
  • transgender women
    • Transgender
    • Women
    • Feminization
    • Studied
    • Hormone
    • Weeks
    • Therapy
    • Also
    • Side
    • Use
    • Antiandrogen
    • Available
  • gonadotropin-releasing hormone
    • Transgender
    • Therapy
    • Studied
    • Women
    • Levels
    • Names
    • Side
    • Use
    • Available
    • Drug
    • First
    • Used

Connections between topic areas Semantic bridges

For Nilutamide, one of the stronger structural bridges in this analysis connects Nilutamide with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Nilutamide — Overview · splits 105 ⟂ 60
Nilutamide — Side effects · splits 131 ⟂ 34
Nilutamide — Medical uses · splits 136 ⟂ 29
Nilutamide — Society and culture · splits 138 ⟂ 27
Nilutamide — Pharmacology · splits 159 ⟂ 6
Nilutamide — History · splits 161 ⟂ 4

Map overview Semantic statistics

Nilutamide

Nodes165
Edges164
Triples111
Avg. degree1.99
Density0.012121
Components1

Source & methodology

TTTA analyzes the structure around Nilutamide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Nilutamide · EN edition · Analysis: TopicsToTalkAbout

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