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Neuronal calcium sensor-1

Neuronal calcium sensor-1 (NCS-1) also known as frequenin homolog (Drosophila) (freq) is a protein that is encoded by the FREQ gene in humans. NCS-1 is a member of the neuronal calcium sensor family, a class of EF hand containing calcium-myristoyl-switch proteins.

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Function

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History

3 related topics

Structure

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Clinical significance

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Key facts & relationships

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Aliases
NCS1, FLUP, FREQ, neuronal calcium sensor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUK, 1G8I, 2LCP, 5AER, 5AFP, 5AEQ
Band
9q34.11 · 2|2 B
Bgee
right frontal lobe · anterior cingulate cortex · nucleus accumbens · amygdala · dorsolateral prefrontal cortex
BioGPS
n/a
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)

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Function

Structure

Clinical significance

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Neuronal calcium sensor-1

Nodes38
Edges37
Triples94
Avg. degree1.95
Density0.052632
Components1

How this topic connects Entity context

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Neuronal calcium sensor-1

Top relations

Gene ontology · 33
Neuronal calcium sensor-1 → axon, calcium ion binding, calcium ion transmembrane transport, calyx of Held, cell junction, cytoplasm, cytoplasmic vesicle, cytosol, dendrite, dense core granule, glutamatergic synapse, Golgi apparatus, intracellular membrane-bounded organelle, magnesium ion binding, membrane, metal ion binding, perinuclear region of cytoplasm, phosphatidylinositol-mediated signaling, plasma membrane, positive regulation of exocytosis
Bgee · 19
Neuronal calcium sensor-1 → amygdala, anterior cingulate cortex, Brodmann area 9, caudate nucleus, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, dorsomedial hypothalamic nucleus, hippocampus proper, medial dorsal nucleus, medial geniculate nucleus, nucleus accumbens, olfactory tubercle, postcentral gyrus, prefrontal cortex, primary visual cortex, right frontal lobe, subiculum, superior frontal gyrus
RNA expression pattern · 19
Neuronal calcium sensor-1 → amygdala, anterior cingulate cortex, Brodmann area 9, caudate nucleus, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, dorsomedial hypothalamic nucleus, hippocampus proper, medial dorsal nucleus, medial geniculate nucleus, nucleus accumbens, olfactory tubercle, postcentral gyrus, prefrontal cortex, primary visual cortex, right frontal lobe, subiculum, superior frontal gyrus
Band · 2
Neuronal calcium sensor-1 → 2|2 B, 9q34.11
Chr. · 2
Neuronal calcium sensor-1 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
Neuronal calcium sensor-1 → 130,237,303 bp, 31,186,001 bp
Aliases · 1
Neuronal calcium sensor-1 → NCS1, FLUP, FREQ, neuronal calcium sensor 1
Available structures · 1
Neuronal calcium sensor-1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUK, 1G8I, 2LCP, 5AER, 5AFP, 5AEQ
BioGPS · 1
Neuronal calcium sensor-1 → n/a
Databases · 1
Neuronal calcium sensor-1 → NCBI: entry; OMA: entry

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Important terminology

ncs-1 calcium bp protein also neuronal chr human band gene chromosome drosophila mouse sensor location function known containing proteins neurotransmission

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Neuronal calcium sensor-1AliasesNCS1, FLUP, FREQ, neuronal calcium sensor 11.00infobox
Neuronal calcium sensor-1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4GUK, 1G8I, 2LCP, 5AER, 5AFP, 5AEQ1.00infobox
Neuronal calcium sensor-1Band9q34.111.00infobox
Neuronal calcium sensor-1Band2|2 B1.00infobox
Neuronal calcium sensor-1Bgeeright frontal lobe1.00infobox
Neuronal calcium sensor-1Bgeeanterior cingulate cortex1.00infobox
Neuronal calcium sensor-1Bgeenucleus accumbens1.00infobox
Neuronal calcium sensor-1Bgeeamygdala1.00infobox
Neuronal calcium sensor-1Bgeedorsolateral prefrontal cortex1.00infobox
Neuronal calcium sensor-1Bgeepostcentral gyrus1.00infobox
Neuronal calcium sensor-1BgeeBrodmann area 91.00infobox
Neuronal calcium sensor-1Bgeeprefrontal cortex1.00infobox
Neuronal calcium sensor-1Bgeecaudate nucleus1.00infobox
Neuronal calcium sensor-1Bgeehippocampus proper1.00infobox
Neuronal calcium sensor-1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
Neuronal calcium sensor-1Bgeesuperior frontal gyrus1.00infobox
Neuronal calcium sensor-1Bgeemedial geniculate nucleus1.00infobox
Neuronal calcium sensor-1Bgeesubiculum1.00infobox
Neuronal calcium sensor-1Bgeemedial dorsal nucleus1.00infobox
Neuronal calcium sensor-1Bgeedorsomedial hypothalamic nucleus1.00infobox
Neuronal calcium sensor-1Bgeeolfactory tubercle1.00infobox
Neuronal calcium sensor-1Bgeeprimary visual cortex1.00infobox
Neuronal calcium sensor-1Bgeecerebellar cortex1.00infobox
Neuronal calcium sensor-1BioGPSn/a1.00infobox
Neuronal calcium sensor-1Chr.Chromosome 9 (human)1.00infobox
Neuronal calcium sensor-1Chr.Chromosome 2 (mouse)1.00infobox
Neuronal calcium sensor-1DatabasesNCBI: entry; OMA: entry1.00infobox
Neuronal calcium sensor-1End130,237,303 bp1.00infobox
Neuronal calcium sensor-1End31,186,001 bp1.00infobox
Neuronal calcium sensor-1EnsemblENSG000001071301.00infobox

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