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KCND3

Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

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Aliases
KCND3, KCND3L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22, BRGDA9, potassium voltage-gated channel subfamily D member 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S1G, 2NZ0
Band
1p13.2 · 3|3 F2.2
Bgee
cerebellar vermis · pars reticulata · lateral nuclear group of thalamus · pars compacta · paraflocculus of cerebellum
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)

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KCND3

Nodes13
Edges12
Triples96
Avg. degree1.85
Density0.153846
Components1

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KCND3

Top relations

Gene ontology · 33
KCND3 → A-type (transient outward) potassium channel activity, cardiac conduction, cell projection, dendrite, GABA-ergic synapse, integral component of membrane, integral component of postsynaptic specialization membrane, ion channel activity, ion transport, membrane, membrane repolarization, membrane repolarization during cardiac muscle cell action potential, membrane repolarization during ventricular cardiac muscle cell action potential, metal ion binding, plasma membrane, potassium channel activity, potassium ion export across plasma membrane, potassium ion transmembrane transport, potassium ion transport, protein binding
Bgee · 20
KCND3 → anterior amygdaloid area, Brodmann area 23, caput epididymis, cerebellar vermis, habenula, lateral geniculate nucleus, lateral nuclear group of thalamus, medial geniculate nucleus, middle temporal gyrus, paraflocculus of cerebellum, parietal lobe, pars compacta, pars reticulata, pineal gland, subiculum, substantia nigra, supraoptic nucleus, tail of epididymis, vas deferens, ventral tegmental area
RNA expression pattern · 20
KCND3 → anterior amygdaloid area, Brodmann area 23, caput epididymis, cerebellar vermis, habenula, lateral geniculate nucleus, lateral nuclear group of thalamus, medial geniculate nucleus, middle temporal gyrus, paraflocculus of cerebellum, parietal lobe, pars compacta, pars reticulata, pineal gland, subiculum, substantia nigra, supraoptic nucleus, tail of epididymis, vas deferens, ventral tegmental area
Band · 2
KCND3 → 1p13.2, 3|3 F2.2
Chr. · 2
KCND3 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
KCND3 → 105,581,318 bp, 111,989,668 bp
Aliases · 1
KCND3 → KCND3, KCND3L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22, BRGDA9, potassium voltage-gated channel subfamily D member 3
Available structures · 1
KCND3 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S1G, 2NZ0
BioGPS · 1
KCND3 → More reference expression data
Databases · 1
KCND3 → NCBI: entry; OMA: entry

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Important terminology

potassium voltage-gated channel bp human gene chr band member kv4 chromosome subfamily action potential location function protein also mouse ion

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
KCND3AliasesKCND3, KCND3L, KCND3S, KSHIVB, KV4.3, SCA19, SCA22, BRGDA9, potassium voltage-gated channel subfamily D member 31.00infobox
KCND3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S1G, 2NZ01.00infobox
KCND3Band1p13.21.00infobox
KCND3Band3|3 F2.21.00infobox
KCND3Bgeecerebellar vermis1.00infobox
KCND3Bgeepars reticulata1.00infobox
KCND3Bgeelateral nuclear group of thalamus1.00infobox
KCND3Bgeepars compacta1.00infobox
KCND3Bgeeparaflocculus of cerebellum1.00infobox
KCND3BgeeBrodmann area 231.00infobox
KCND3Bgeemiddle temporal gyrus1.00infobox
KCND3Bgeetail of epididymis1.00infobox
KCND3Bgeeparietal lobe1.00infobox
KCND3Bgeecaput epididymis1.00infobox
KCND3Bgeesubstantia nigra1.00infobox
KCND3Bgeeventral tegmental area1.00infobox
KCND3Bgeelateral geniculate nucleus1.00infobox
KCND3Bgeemedial geniculate nucleus1.00infobox
KCND3Bgeehabenula1.00infobox
KCND3Bgeevas deferens1.00infobox
KCND3Bgeeanterior amygdaloid area1.00infobox
KCND3Bgeesubiculum1.00infobox
KCND3Bgeepineal gland1.00infobox
KCND3Bgeesupraoptic nucleus1.00infobox
KCND3BioGPSMore reference expression data1.00infobox
KCND3Chr.Chromosome 1 (human)1.00infobox
KCND3Chr.Chromosome 3 (mouse)1.00infobox
KCND3DatabasesNCBI: entry; OMA: entry1.00infobox
KCND3End111,989,668 bp1.00infobox
KCND3End105,581,318 bp1.00infobox

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