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Geminin

Geminin, DNA replication inhibitor, also known as GMNN, is a protein in humans encoded by the GMNN gene. A nuclear protein present in most eukaryotes and highly conserved across species, numerous functions have been elucidated for geminin including roles in metazoan cell cycle, cellular proliferation, cell lineage commitment, and neural differentiation.…

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Aliases
GMNN, Gem, MGORS6, geminin, DNA replication inhibitor, geminin DNA replication inhibitor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1T6F, 1UII, 2LP0, 2WVR, 4BRY
Band
6p22.3 · 13|13 A3.1
Bgee
oocyte · body of pancreas · secondary oocyte · gonad · mucosa of transverse colon
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 13 (mouse)

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Map overview Semantic statistics

Geminin

Nodes33
Edges32
Triples103
Avg. degree1.94
Density0.060606
Components1

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Geminin

Top relations

Gene ontology · 19
Geminin → animal organ morphogenesis, cell cycle, chromatin binding, cytoplasm, cytosol, DNA replication preinitiation complex assembly, G1/S transition of mitotic cell cycle, histone deacetylase binding, negative regulation of cell cycle, negative regulation of DNA replication, negative regulation of DNA-dependent DNA replication, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus, positive regulation of chromatin binding, protein binding, protein-containing complex assembly, regulation of DNA replication, transcription corepressor activity
Bgee · 18
Geminin → blastocyst, body of pancreas, embryo, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, medial ganglionic eminence, morula, mucosa of sigmoid colon, mucosa of transverse colon, oocyte, Paneth cell, primitive streak, rectum, secondary oocyte, ventricular zone, yolk sac
RNA expression pattern · 18
Geminin → blastocyst, body of pancreas, embryo, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, medial ganglionic eminence, morula, mucosa of sigmoid colon, mucosa of transverse colon, oocyte, Paneth cell, primitive streak, rectum, secondary oocyte, ventricular zone, yolk sac
related to External links · 12
Geminin → GMNN, Human Geminin, Medicine Medical Subject Headings, MeSH, Mouse Geminin, National Library, O75496, O88513, Overview, PDB, PDBe-KB, UniProt
related to Developmental control · 5
Geminin → In, SWI/SNF, This, Ultimately, When
related to history · 3
Geminin → Coincidentally, DNA, Xenopus
Band · 2
Geminin → 13|13 A3.1, 6p22.3
Chr. · 2
Geminin → Chromosome 13 (mouse), Chromosome 6 (human)
End · 2
Geminin → 24,786,099 bp, 24,945,906 bp
related to Cell cycle control · 2
Geminin → G1, G2

Important terminology Word statistics

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Important terminology

cell human dna replication bp neural protein chr band cycle gmnn complex gene chromosome function lines mouse inhibitor location pdb

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GemininAliasesGMNN, Gem, MGORS6, geminin, DNA replication inhibitor, geminin DNA replication inhibitor1.00infobox
GemininAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1T6F, 1UII, 2LP0, 2WVR, 4BRY1.00infobox
GemininBand6p22.31.00infobox
GemininBand13|13 A3.11.00infobox
GemininBgeeoocyte1.00infobox
GemininBgeebody of pancreas1.00infobox
GemininBgeesecondary oocyte1.00infobox
GemininBgeegonad1.00infobox
GemininBgeemucosa of transverse colon1.00infobox
GemininBgeeventricular zone1.00infobox
GemininBgeeembryo1.00infobox
GemininBgeerectum1.00infobox
GemininBgeeganglionic eminence1.00infobox
GemininBgeemucosa of sigmoid colon1.00infobox
GemininBgeeprimitive streak1.00infobox
GemininBgeefetal liver hematopoietic progenitor cell1.00infobox
GemininBgeemorula1.00infobox
GemininBgeeyolk sac1.00infobox
GemininBgeePaneth cell1.00infobox
GemininBgeemedial ganglionic eminence1.00infobox
GemininBgeeblastocyst1.00infobox
GemininBgeeepiblast1.00infobox
GemininBioGPSMore reference expression data1.00infobox
GemininChr.Chromosome 6 (human)1.00infobox
GemininChr.Chromosome 13 (mouse)1.00infobox
GemininDatabasesNCBI: entry; OMA: entry1.00infobox
GemininEnd24,786,099 bp1.00infobox
GemininEnd24,945,906 bp1.00infobox
GemininEnsemblENSG000001123121.00infobox
GemininEntrez510531.00infobox

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