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Multiple sequence alignment (MSA) is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. These alignments are used to infer evolutionary relationships via phylogenetic analysis and can highlight homologous features between sequences. Alignments highlight mutation events such as point…
Regions, Alignment methods & Overview
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alignment sequence sequences alignments multiple msa methods used method progressive set regions program using use protein uses pairwise approach evolutionary
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| point mutations | instance of | Alignments highlight mutation events | 0.80 | text |
| neighbor-joining or unweighted pair group method with arithmetic mean | instance of | The initial guide tree is determined by an efficient clustering method | 0.80 | text |
| finding a high-quality alignment score.A variety of subtly different iteration methods have been implemented | instance of | iterative methods can return to previously calculated pairwise alignments or sub-MSAs incorporating subsets of the query sequence as a means of optimizing a general objective fu… | 0.80 | text |
| made available in software packages | instance of | iterative methods can return to previously calculated pairwise alignments or sub-MSAs incorporating subsets of the query sequence as a means of optimizing a general objective fu… | 0.80 | text |
| detection of positive selection | instance of | and these regions might be desirable for other purposes | 0.80 | text |
| Multiple sequence alignment | has method | Consensus | 0.60 | section |
| Multiple sequence alignment | has method | There | 0.60 | section |
| Multiple sequence alignment | has method | M-COFFEE | 0.60 | section |
| Multiple sequence alignment | has method | MergeAlign | 0.60 | section |
| Multiple sequence alignment | has method | The | 0.60 | section |
| Multiple sequence alignment | has method | Most | 0.60 | section |
| Multiple sequence alignment | has method | This | 0.60 | section |
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