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MAFFT: History, Accuracy and results & Algorithm

In bioinformatics, MAFFT (multiple alignment using fast Fourier transform) is a program used to create multiple sequence alignments of amino acid or nucleotide sequences. Published in 2002, the first version used an algorithm based on progressive alignment, in which the sequences were clustered with the help of the fast Fourier transform. Subsequent…

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MAFFT topic overview

The analysis highlights History, Accuracy and results and Algorithm as prominent areas in the source structure around MAFFT.

Related topics
12
Source areas
5
Connected nodes
17
Extracted relationships
75
Concept neighborhoods
12
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics
Accuracy and results · 3 topics
Algorithm · 1 topics
History · 1 topics
Settings · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Developer
Kazutaka Katoh
Licence
BSD, GPL, others
Operating system
Unix, Linux, Mac, Windows
Release
2002; 24 years ago (2002)
Stable release
7.526 / April 2024; 2 years ago (2024-04)
Type
Bioinformatics tool

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Algorithm

Settings

Accuracy and results

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MAFFT connects Entity context

The extracted context around MAFFT shows recurring relationship patterns in the source. For example, MAFFT → Adjusting, BLAST, BLASTP, BLOSUM50, BLOSUM62, Deep, Different, FASTA, Gap Extension Penalty, Gap Open Penalty, In, Protein, Scoring Matrix, SEARCH, SSEARCH, The, There, UNIT, VTML10, VTML80 Another extracted example is MAFFT → Because, ClustalW, CPU, FFT, For, Fourier, In, Later, MAFFT's FFT-NS-2, Needleman-Wunsch, RNA, T-Coffee, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAFFT

Top relations

related to Settings · 20
MAFFT → Adjusting, BLAST, BLASTP, BLOSUM50, BLOSUM62, Deep, Different, FASTA, Gap Extension Penalty, Gap Open Penalty, In, Protein, Scoring Matrix, SEARCH, SSEARCH, The, There, UNIT, VTML10, VTML80
related to Accuracy and results · 13
MAFFT → Because, ClustalW, CPU, FFT, For, Fourier, In, Later, MAFFT's FFT-NS-2, Needleman-Wunsch, RNA, T-Coffee, This
related to history · 11
MAFFT → CPU, December, Fourier, It, Kazutaka Katoh, MSA, MSAs, One, The, There, This
related to Algorithm · 8
MAFFT → Distance Calculation, Guide Tree Construction, Iterative Refinement, Pairwise Alignment, Progressive Alignment, The, The MAFFT, This
related to External links · 7
MAFFT → ClustalW, EBIMultiple Sequence Alignment, GenomeNetSIB MyHits, Official, Online ServerMAFFT, PRRN, T-Coffee
Developer · 1
MAFFT → Kazutaka Katoh
Licence · 1
MAFFT → BSD, GPL, others
Operating system · 1
MAFFT → Unix, Linux, Mac, Windows
Release · 1
MAFFT → 2002; 24 years ago (2002)
Stable release · 1
MAFFT → 7.526 / April 2024; 2 years ago (2024-04)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

alignment sequences sequence algorithm alignments accuracy multiple time algorithms used complexity gap using fast fourier transform scoring guide distance tree

MAFFT relationships Subject–Predicate–Object triples

TTTA extracted 75 structured relationships around MAFFT. Examples in this analysis include MAFFT → Developer → Kazutaka Katoh and MAFFT → Licence → BSD, GPL, others. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAFFTDeveloperKazutaka Katoh1.00infobox
MAFFTLicenceBSD, GPL, others1.00infobox
MAFFTOperating systemUnix, Linux, Mac, Windows1.00infobox
MAFFTRelease2002; 24 years ago (2002)1.00infobox
MAFFTStable release7.526 / April 2024; 2 years ago (2024-04)1.00infobox
MAFFTTypeBioinformatics tool1.00infobox
MAFFTWebsitemafft.cbrc.jp/alignment/software1.00infobox
MAFFTWritten inC1.00infobox
ClustalWinstance ofstudies have shown that MAFFT performs exceptionally well when compared to other popular algorithms0.80text
T-Coffeeinstance ofstudies have shown that MAFFT performs exceptionally well when compared to other popular algorithms0.80text
particularly for larger datasetsinstance ofstudies have shown that MAFFT performs exceptionally well when compared to other popular algorithms0.80text
sequences with high degrees of divergenceinstance ofstudies have shown that MAFFT performs exceptionally well when compared to other popular algorithms0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around MAFFT bring nearby vocabulary together. In this analysis, examples include Accuracy, Algorithms and Multiple. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MAFFT
    • Accuracy
    • Algorithms
    • Multiple
    • Released
    • T-coffee
    • Sequence
    • Software
    • Generation
    • Sequences
    • Algorithm
    • Settings
    • Version
  • mafft
    • Accuracy
    • Algorithms
    • Multiple
    • Released
    • T-coffee
    • Sequence
    • Software
    • Generation
    • Sequences
    • Algorithm
    • Settings
    • Version
  • progressive alignment
    • Version
    • Sequence
    • Mafft
    • Algorithm
    • Multiple
    • Transform
    • Sequences
    • Guide
    • Tree
    • Used
    • Progressive
    • Accuracy
  • algorithm
    • Version
    • Fast
    • Fourier
    • Progressive
    • Transform
    • Alignment
    • Sequences
    • Based
    • First
    • Pairwise
    • Settings
    • Guide
  • accuracy and results
    • Alignments
    • Mafft
    • Algorithms
    • Generation
    • Refinement
    • Alignment
    • Iterative
    • Sequences
    • Bioinformatics
    • Software
    • Based
    • First
  • bioinformatics
    • Fast
    • Fourier
    • Transform
    • Used
    • Multiple
    • Software
    • Based
    • First
    • Input
    • Mafft
    • Settings
    • Version
  • distance matrix
    • Calculation
    • Scoring
    • Matrix
    • Pairwise
    • Using
    • Guide
    • Tree
    • Complexity
    • Time
    • Settings
    • Sequences
    • Penalty
  • fast fourier transform
    • Fourier
    • Transform
    • Used
    • Based
    • First
    • Version
    • Algorithm
    • Progressive
    • Sequences
    • Software
    • Input
    • Settings

Connections between topic areas Semantic bridges

For MAFFT, one of the stronger structural bridges in this analysis connects MAFFT with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAFFTOverview · splits 11 ⟂ 7
MAFFTAccuracy and results · splits 14 ⟂ 4

Map overview Semantic statistics

MAFFT

Nodes18
Edges17
Triples75
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around MAFFT to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Accuracy and results & Algorithm, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAFFT · EN edition · Analysis: TopicsToTalkAbout

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