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Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins. MUC-16 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, most notably ovarian…
The analysis highlights Structure, Role in cancer and Function as prominent areas in the source structure around Mucin-16.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Mucin-16 shows recurring relationship patterns in the source. For example, Mucin-16 → cell adhesion, extracellular exosome, extracellular region, extracellular space, extrinsic component of membrane, Golgi lumen, integral component of membrane, membrane, O-glycan processing, plasma membrane, protein binding, stimulatory C-type lectin receptor signaling pathway, vesicle Another extracted example is Mucin-16 → bronchial epithelial cell, epithelium of bronchus, epithelium of nasopharynx, minor salivary glands, mucosa of paranasal sinus, nasal epithelium, olfactory zone of nasal mucosa, palpebral conjunctiva, right uterine tube, trachea. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
muc16 cancer cell ovarian tumor ca-125 also mesothelin human domain cells protein mucin gene muc-16 extracellular bp may location surface
TTTA extracted 54 structured relationships around Mucin-16. Examples in this analysis include Mucin-16 → Aliases → MUC16, CA125, mucin 16, cell surface associated and Mucin-16 → Band → 19p13.2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Mucin-16 | Aliases | MUC16, CA125, mucin 16, cell surface associated | 1.00 | infobox |
| Mucin-16 | Band | 19p13.2 | 1.00 | infobox |
| Mucin-16 | Bgee | nasal epithelium | 1.00 | infobox |
| Mucin-16 | Bgee | epithelium of bronchus | 1.00 | infobox |
| Mucin-16 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| Mucin-16 | Bgee | bronchial epithelial cell | 1.00 | infobox |
| Mucin-16 | Bgee | mucosa of paranasal sinus | 1.00 | infobox |
| Mucin-16 | Bgee | palpebral conjunctiva | 1.00 | infobox |
| Mucin-16 | Bgee | trachea | 1.00 | infobox |
| Mucin-16 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| Mucin-16 | Bgee | right uterine tube | 1.00 | infobox |
| Mucin-16 | Bgee | minor salivary glands | 1.00 | infobox |
| Mucin-16 | BioGPS | n/a | 1.00 | infobox |
| Mucin-16 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| Mucin-16 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Mucin-16 | End | 8,981,342 bp | 1.00 | infobox |
| Mucin-16 | Ensembl | ENSG00000181143 | 1.00 | infobox |
| Mucin-16 | Entrez | 94025 | 1.00 | infobox |
| Mucin-16 | External IDs | OMIM: 606154; GeneCards: MUC16 | 1.00 | infobox |
| Mucin-16 | Gene location (Human) | Gene location (Human)Chr.Chromosome 19 (human)Band19p13.2Start8,848,844 bpEnd8,981,342 bp | 1.00 | infobox |
| Mucin-16 | Gene ontology | protein binding | 1.00 | infobox |
| Mucin-16 | Gene ontology | Golgi lumen | 1.00 | infobox |
| Mucin-16 | Gene ontology | integral component of membrane | 1.00 | infobox |
| Mucin-16 | Gene ontology | extracellular region | 1.00 | infobox |
| Mucin-16 | Gene ontology | vesicle | 1.00 | infobox |
| Mucin-16 | Gene ontology | extracellular exosome | 1.00 | infobox |
| Mucin-16 | Gene ontology | membrane | 1.00 | infobox |
| Mucin-16 | Gene ontology | extrinsic component of membrane | 1.00 | infobox |
| Mucin-16 | Gene ontology | extracellular space | 1.00 | infobox |
| Mucin-16 | Gene ontology | plasma membrane | 1.00 | infobox |
The concept neighborhoods around Mucin-16 bring nearby vocabulary together. In this analysis, examples include Cytoplasmic, Extracellular and Domain. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Mucin-16, one of the stronger structural bridges in this analysis connects Mucin-16 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Mucin-16 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Role in cancer & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Mucin-16 · EN edition · Analysis: TopicsToTalkAbout