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A morphogen is a signaling molecule that contributes to morphogenesis and pattern formation, which are key processes in developmental biology. Morphogens help organize tissues by creating spatial and temporal differences in signaling activity.
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morphogens cells genes drosophila signaling transcription gene expression target factors model cell developmental tissue mechanisms development also concentration activity signal
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Morphogen | is a | signaling molecule that contributes to morphogenesis and pattern formation | 0.90 | text |
| active transport | instance of | Mechanisms | 0.80 | text |
| cytoneme-mediated signaling | instance of | Mechanisms | 0.80 | text |
| extracellular vesicles | instance of | Mechanisms | 0.80 | text |
| and relay signaling contribute to dynamic or spatially complex gradients.Spatial differences in morphogen signaling interact with feedback loops | instance of | Mechanisms | 0.80 | text |
| tissue mechanics | instance of | Mechanisms | 0.80 | text |
| and gene regulatory networks | instance of | Mechanisms | 0.80 | text |
| Hedgehog | instance of | morphogens are secreted signaling proteins that act between cells through pathways | 0.80 | text |
| Wnt | instance of | morphogens are secreted signaling proteins that act between cells through pathways | 0.80 | text |
| BMP | instance of | morphogens are secreted signaling proteins that act between cells through pathways | 0.80 | text |
| and Nodal.Although the classical gradient model has been highly influential | instance of | morphogens are secreted signaling proteins that act between cells through pathways | 0.80 | text |
| many developmental systems use additional or alternative mechanisms | instance of | morphogens are secreted signaling proteins that act between cells through pathways | 0.80 | text |
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