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PTCH1

Protein patched homolog 1 is a protein that is the member of the patched family and in humans is encoded by the PTCH1 gene.

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Aliases
PTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, patched 1
Band
9q22.32 · 13 B3|13 32.8 cM
Bgee
tibia · spinal ganglia · trigeminal ganglion · sural nerve · pylorus
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 13 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Clinical significance

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Map overview Semantic statistics

PTCH1

Nodes19
Edges18
Triples162
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

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PTCH1

Top relations

Gene ontology · 85
PTCH1 → animal organ morphogenesis, axonal growth cone, brain development, branching involved in ureteric bud morphogenesis, caveola, cell differentiation involved in kidney development, cell fate determination, cell proliferation involved in metanephros development, cellular response to cholesterol, cholesterol binding, ciliary membrane, cilium, commissural neuron axon guidance, cyclin binding, dendritic growth cone, dorsal/ventral neural tube patterning, dorsal/ventral pattern formation, embryonic limb morphogenesis, embryonic organ development, endocytic vesicle membrane
Bgee · 20
PTCH1 → cardia, dermis, endometrium, Gonadal ridge, hair follicle, internal globus pallidus, lobe of cerebellum, migratory enteric neural crest cell, molar, pylorus, retinal pigment epithelium, sciatic nerve, sperm, spinal ganglia, sural nerve, tibia, tooth, trigeminal ganglion, upper jaw, vas deferens
RNA expression pattern · 20
PTCH1 → cardia, dermis, endometrium, Gonadal ridge, hair follicle, internal globus pallidus, lobe of cerebellum, migratory enteric neural crest cell, molar, pylorus, retinal pigment epithelium, sciatic nerve, sperm, spinal ganglia, sural nerve, tibia, tooth, trigeminal ganglion, upper jaw, vas deferens
related to Clinical significance · 8
PTCH1 → Additional, AKA Gorlin's Syndrome, Alternative, Gorlin, In, Mutations, SNPs, Some
related to External links · 6
PTCH1 → GeneReviews/NCBI/NIH/UW, MicrodeletionDrosophila, Nevoid Basal Cell Carcinoma, SyndromeGeneReviews/NCBI/NIH/UW, The Interactive FlyPTCH1, UCSC Genome Browser
Band · 2
PTCH1 → 13 B3|13 32.8 cM, 9q22.32
Chr. · 2
PTCH1 → Chromosome 13 (mouse), Chromosome 9 (human)
End · 2
PTCH1 → 63,721,412 bp, 95,517,057 bp
related to Function · 2
PTCH1 → The PTCH1, This
Aliases · 1
PTCH1 → PTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, patched 1

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Important terminology

gene human bp patched chr band chromosome location protein cell family holoprosencephaly mouse hedgehog ucsc function external mutations associated syndrome

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PTCH1AliasesPTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, patched 11.00infobox
PTCH1Band9q22.321.00infobox
PTCH1Band13 B3|13 32.8 cM1.00infobox
PTCH1Bgeetibia1.00infobox
PTCH1Bgeespinal ganglia1.00infobox
PTCH1Bgeetrigeminal ganglion1.00infobox
PTCH1Bgeesural nerve1.00infobox
PTCH1Bgeepylorus1.00infobox
PTCH1Bgeesperm1.00infobox
PTCH1Bgeeretinal pigment epithelium1.00infobox
PTCH1Bgeecardia1.00infobox
PTCH1Bgeeinternal globus pallidus1.00infobox
PTCH1Bgeeendometrium1.00infobox
PTCH1Bgeeupper jaw1.00infobox
PTCH1BgeeGonadal ridge1.00infobox
PTCH1Bgeetooth1.00infobox
PTCH1Bgeemolar1.00infobox
PTCH1Bgeevas deferens1.00infobox
PTCH1Bgeemigratory enteric neural crest cell1.00infobox
PTCH1Bgeelobe of cerebellum1.00infobox
PTCH1Bgeesciatic nerve1.00infobox
PTCH1Bgeehair follicle1.00infobox
PTCH1Bgeedermis1.00infobox
PTCH1BioGPSMore reference expression data1.00infobox
PTCH1Chr.Chromosome 9 (human)1.00infobox
PTCH1Chr.Chromosome 13 (mouse)1.00infobox
PTCH1DatabasesNCBI: entry; OMA: entry1.00infobox
PTCH1End95,517,057 bp1.00infobox
PTCH1End63,721,412 bp1.00infobox
PTCH1EnsemblENSG000001859201.00infobox

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