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Protein patched homolog 1 is a protein that is the member of the patched family and in humans is encoded by the PTCH1 gene.
The analysis highlights Clinical significance, Function and Overview as prominent areas in the source structure around PTCH1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PTCH1 shows recurring relationship patterns in the source. For example, PTCH1 → animal organ morphogenesis, axonal growth cone, brain development, branching involved in ureteric bud morphogenesis, caveola, cell differentiation involved in kidney development, cell fate determination, cell proliferation involved in metanephros development, cellular response to cholesterol, cholesterol binding, ciliary membrane, cilium, commissural neuron axon guidance, cyclin binding, dendritic growth cone, dorsal/ventral neural tube patterning, dorsal/ventral pattern formation, embryonic limb morphogenesis, embryonic organ development, endocytic vesicle membrane Another extracted example is PTCH1 → cardia, dermis, endometrium, Gonadal ridge, hair follicle, internal globus pallidus, lobe of cerebellum, migratory enteric neural crest cell, molar, pylorus, retinal pigment epithelium, sciatic nerve, sperm, spinal ganglia, sural nerve, tibia, tooth, trigeminal ganglion, upper jaw, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene human bp patched chr band chromosome location protein cell family holoprosencephaly mouse hedgehog ucsc function external mutations associated syndrome
TTTA extracted 162 structured relationships around PTCH1. Examples in this analysis include PTCH1 → Aliases → PTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, patched 1 and PTCH1 → Band → 9q22.32. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PTCH1 | Aliases | PTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, patched 1 | 1.00 | infobox |
| PTCH1 | Band | 9q22.32 | 1.00 | infobox |
| PTCH1 | Band | 13 B3|13 32.8 cM | 1.00 | infobox |
| PTCH1 | Bgee | tibia | 1.00 | infobox |
| PTCH1 | Bgee | spinal ganglia | 1.00 | infobox |
| PTCH1 | Bgee | trigeminal ganglion | 1.00 | infobox |
| PTCH1 | Bgee | sural nerve | 1.00 | infobox |
| PTCH1 | Bgee | pylorus | 1.00 | infobox |
| PTCH1 | Bgee | sperm | 1.00 | infobox |
| PTCH1 | Bgee | retinal pigment epithelium | 1.00 | infobox |
| PTCH1 | Bgee | cardia | 1.00 | infobox |
| PTCH1 | Bgee | internal globus pallidus | 1.00 | infobox |
| PTCH1 | Bgee | endometrium | 1.00 | infobox |
| PTCH1 | Bgee | upper jaw | 1.00 | infobox |
| PTCH1 | Bgee | Gonadal ridge | 1.00 | infobox |
| PTCH1 | Bgee | tooth | 1.00 | infobox |
| PTCH1 | Bgee | molar | 1.00 | infobox |
| PTCH1 | Bgee | vas deferens | 1.00 | infobox |
| PTCH1 | Bgee | migratory enteric neural crest cell | 1.00 | infobox |
| PTCH1 | Bgee | lobe of cerebellum | 1.00 | infobox |
| PTCH1 | Bgee | sciatic nerve | 1.00 | infobox |
| PTCH1 | Bgee | hair follicle | 1.00 | infobox |
| PTCH1 | Bgee | dermis | 1.00 | infobox |
| PTCH1 | BioGPS | More reference expression data | 1.00 | infobox |
| PTCH1 | Chr. | Chromosome 9 (human) | 1.00 | infobox |
| PTCH1 | Chr. | Chromosome 13 (mouse) | 1.00 | infobox |
| PTCH1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PTCH1 | End | 95,517,057 bp | 1.00 | infobox |
| PTCH1 | End | 63,721,412 bp | 1.00 | infobox |
| PTCH1 | Ensembl | ENSG00000185920 | 1.00 | infobox |
The concept neighborhoods around PTCH1 bring nearby vocabulary together. In this analysis, examples include Also, Found and Ucsc. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PTCH1, one of the stronger structural bridges in this analysis connects PTCH1 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PTCH1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PTCH1 · EN edition · Analysis: TopicsToTalkAbout