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Methyl-CpG-binding domain protein 2: Function, Interactions & Overview

Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene.

Language: English [EN]
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Methyl-CpG-binding domain protein 2 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around Methyl-CpG-binding domain protein 2.

Related topics
15
Source areas
3
Connected nodes
18
Extracted relationships
108
Related term clusters
12
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 7 topics
Interactions · 6 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MBD2, DMTase, NY-CO-41, methyl-CpG binding domain protein 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L2L
Band
18q21.2 · 18 E2|18 44.54 cM
Bgee
gingival epithelium · tonsil · epithelium of colon · oral cavity · bone marrow cell
BioGPS
More reference expression data
Chr.
Chromosome 18 (human) · Chromosome 18 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Methyl-CpG-binding domain protein 2 connects Entity context

The extracted context around Methyl-CpG-binding domain protein 2 shows recurring relationship patterns in the source. For example, Methyl-CpG-binding domain protein 2 → ageing, C2H2 zinc finger domain binding, cellular response to organic cyclic compound, chromatin, chromatin binding, cytoplasm, cytosol, development of the heart, DNA binding, DNA methylation-dependent heterochromatin assembly, embryonic organ development, heterochromatin, histone deacetylase complex, Maternal behavior, methyl-CpG binding, mRNA binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nucleoplasm, nucleosomal DNA binding Another extracted example is Methyl-CpG-binding domain protein 2 → aortic valve, ascending aorta, bone marrow cell, epithelium of colon, epithelium of female urethra, epithelium of male urethra, epithelium of urethra, gingival epithelium, granulocyte, hair follicle, lip, monocyte, mucosa of esophagus, oral cavity, Paneth cell, parotid gland, submandibular gland, sural nerve, tonsil, white blood cell. Use these groups to spot repeated connection types before inspecting the individual relationships.

Methyl-CpG-binding domain protein 2

Top relations

Gene ontology · 38
Methyl-CpG-binding domain protein 2 → ageing, C2H2 zinc finger domain binding, cellular response to organic cyclic compound, chromatin, chromatin binding, cytoplasm, cytosol, development of the heart, DNA binding, DNA methylation-dependent heterochromatin assembly, embryonic organ development, heterochromatin, histone deacetylase complex, Maternal behavior, methyl-CpG binding, mRNA binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nucleoplasm, nucleosomal DNA binding
Bgee · 20
Methyl-CpG-binding domain protein 2 → aortic valve, ascending aorta, bone marrow cell, epithelium of colon, epithelium of female urethra, epithelium of male urethra, epithelium of urethra, gingival epithelium, granulocyte, hair follicle, lip, monocyte, mucosa of esophagus, oral cavity, Paneth cell, parotid gland, submandibular gland, sural nerve, tonsil, white blood cell
RNA expression pattern · 20
Methyl-CpG-binding domain protein 2 → aortic valve, ascending aorta, bone marrow cell, epithelium of colon, epithelium of female urethra, epithelium of male urethra, epithelium of urethra, gingival epithelium, granulocyte, hair follicle, lip, monocyte, mucosa of esophagus, oral cavity, Paneth cell, parotid gland, submandibular gland, sural nerve, tonsil, white blood cell
related to Interactions · 6
Methyl-CpG-binding domain protein 2 → GATAD2B, HDAC1, Histone, MBD3HINFP, Methyl-CpG-binding, MIZF
Band · 2
Methyl-CpG-binding domain protein 2 → 18 E2|18 44.54 cM, 18q21.2
Chr. · 2
Methyl-CpG-binding domain protein 2 → Chromosome 18 (human), Chromosome 18 (mouse)
End · 2
Methyl-CpG-binding domain protein 2 → 54,224,669 bp, 70,759,202 bp
Aliases · 1
Methyl-CpG-binding domain protein 2 → MBD2, DMTase, NY-CO-41, methyl-CpG binding domain protein 2
Available structures · 1
Methyl-CpG-binding domain protein 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L2L
BioGPS · 1
Methyl-CpG-binding domain protein 2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mbd2 bp protein human gene chr band domain mbd3 chromosome 18 binding dna location function methyl-cpg-binding mouse methylation methylated encoded

Methyl-CpG-binding domain protein 2 relationships Subject–Predicate–Object triples

TTTA extracted 108 structured relationships around Methyl-CpG-binding domain protein 2. Examples in this analysis include Methyl-CpG-binding domain protein 2 → Aliases → MBD2, DMTase, NY-CO-41, methyl-CpG binding domain protein 2 and Methyl-CpG-binding domain protein 2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L2L. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Methyl-CpG-binding domain protein 2AliasesMBD2, DMTase, NY-CO-41, methyl-CpG binding domain protein 21.00infobox
Methyl-CpG-binding domain protein 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L2L1.00infobox
Methyl-CpG-binding domain protein 2Band18q21.21.00infobox
Methyl-CpG-binding domain protein 2Band18 E2|18 44.54 cM1.00infobox
Methyl-CpG-binding domain protein 2Bgeegingival epithelium1.00infobox
Methyl-CpG-binding domain protein 2Bgeetonsil1.00infobox
Methyl-CpG-binding domain protein 2Bgeeepithelium of colon1.00infobox
Methyl-CpG-binding domain protein 2Bgeeoral cavity1.00infobox
Methyl-CpG-binding domain protein 2Bgeebone marrow cell1.00infobox
Methyl-CpG-binding domain protein 2Bgeeparotid gland1.00infobox
Methyl-CpG-binding domain protein 2Bgeewhite blood cell1.00infobox
Methyl-CpG-binding domain protein 2Bgeesural nerve1.00infobox
Methyl-CpG-binding domain protein 2Bgeemucosa of esophagus1.00infobox
Methyl-CpG-binding domain protein 2Bgeemonocyte1.00infobox
Methyl-CpG-binding domain protein 2Bgeeepithelium of urethra1.00infobox
Methyl-CpG-binding domain protein 2Bgeegranulocyte1.00infobox
Methyl-CpG-binding domain protein 2BgeePaneth cell1.00infobox
Methyl-CpG-binding domain protein 2Bgeeepithelium of male urethra1.00infobox
Methyl-CpG-binding domain protein 2Bgeeepithelium of female urethra1.00infobox
Methyl-CpG-binding domain protein 2Bgeehair follicle1.00infobox
Methyl-CpG-binding domain protein 2Bgeeaortic valve1.00infobox
Methyl-CpG-binding domain protein 2Bgeeascending aorta1.00infobox
Methyl-CpG-binding domain protein 2Bgeelip1.00infobox
Methyl-CpG-binding domain protein 2Bgeesubmandibular gland1.00infobox
Methyl-CpG-binding domain protein 2BioGPSMore reference expression data1.00infobox
Methyl-CpG-binding domain protein 2Chr.Chromosome 18 (human)1.00infobox
Methyl-CpG-binding domain protein 2Chr.Chromosome 18 (mouse)1.00infobox
Methyl-CpG-binding domain protein 2DatabasesNCBI: entry; OMA: entry1.00infobox
Methyl-CpG-binding domain protein 2End54,224,669 bp1.00infobox
Methyl-CpG-binding domain protein 2End70,759,202 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Methyl-CpG-binding domain protein 2 bring nearby vocabulary together. In this analysis, examples include Methyl-cpg-binding, Methyl-cpg and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Methyl-CpG-binding domain protein 2
    • Methyl-cpg-binding
    • Methyl-cpg
    • Search
    • Biological
    • Function
    • Location
    • Mbd3
    • Binding
    • Chromosome
    • Protein
    • Bp
    • Chr
  • methyl-cpg-binding domain protein 2
    • Methyl-cpg-binding
    • Protein
    • Mbd2
    • Gene
    • Human
    • Deacetylase
    • Histone
    • Methyl-cpg
    • Search
    • Biological
    • Function
    • Location
  • gene
    • Location
    • Chromosome
    • Mbd2
    • Bp
    • Chr
    • Human
    • E2
    • End
    • Methyl-cpg
    • Mouse
    • Search
    • Transcription
  • mbd2
    • Gene
    • Protein
    • Binding
    • Human
    • Mbd3
    • Complex
    • Mbd1
    • Mecp2
    • Methyl-cpg
    • Nurd
    • Search
    • Transcription
  • methyl-cpg-binding domain
    • Methyl-cpg-binding
    • Protein
    • Mbd2
    • Gene
    • Human
    • Deacetylase
    • Histone
    • Methyl-cpg
    • Search
    • Function
    • Location
    • Mbd3
  • function
    • Biological
    • Methyl-cpg
    • Methylation
    • Search
    • Location
    • Protein
    • Binding
    • Chromosome
    • Bp
    • Chr
    • Development
    • Gene
  • histone deacetylase 2
    • Deacetylase
    • Histone
    • Development
    • Domain
    • Complex
    • E2
    • End
    • Methyl-cpg
    • Methylation
    • Mouse
    • Protein
    • Search
  • protein
    • Biological
    • Deacetylase
    • Histone
    • Methylation
    • Search
    • Mbd3
    • Development
    • Complex
    • E2
    • End
    • Mouse
    • Nurd

Connections between topic areas Semantic bridges

For Methyl-CpG-binding domain protein 2, one of the stronger structural bridges in this analysis connects Methyl-CpG-binding domain protein 2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Methyl-CpG-binding domain protein 2 — Function · splits 11 ⟂ 8
Methyl-CpG-binding domain protein 2 — Interactions · splits 12 ⟂ 7
Methyl-CpG-binding domain protein 2 — Overview · splits 16 ⟂ 3

Map overview Semantic statistics

Methyl-CpG-binding domain protein 2

Nodes19
Edges18
Triples108
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around Methyl-CpG-binding domain protein 2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Methyl-CpG-binding domain protein 2 · EN edition · Analysis: TopicsToTalkAbout

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