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MEF2B: Art & Regions

Myocyte enhancer binding factor 2B (MEF2B) is a transcription factor part of the MEF2 gene family including MEF2A, MEF2C, and MEF2D. However, MEF2B is distant from the other three branches of MEF2 genes as it lacks the protein-coding Holliday junction recognition protein C-terminal (HJURP_C) region in vertebrates.

Language: English [EN]
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MEF2B topic overview

The analysis highlights Art and Regions as prominent areas in the source structure around MEF2B.

Related topics
6
Source areas
3
Connected nodes
9
Extracted relationships
44
Concept neighborhoods
7
Bridge connections
9

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 3 topics
Interactions · 2 topics
Clinical relevance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BORCS8-MEF2B, LOC729991-MEF2B, MEF2B, MEF2BNB-MEF2B, BORCS8-MEF2B readthrough, RSRFR2
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1N6J, 1TQE
Databases
NCBI: entry; OMA: entry
Ensembl
ENSG00000064489
Entrez
4207
External IDs
GeneCards: BORCS8-MEF2B

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Clinical relevance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MEF2B connects Entity context

The extracted context around MEF2B shows recurring relationship patterns in the source. For example, MEF2B → DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, histone deacetylase binding, muscle organ development, nucleus, positive regulation of transcription by RNA polymerase II, protein dimerization activity, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription by RNA polymerase II, transcription regulator complex, transcription, DNA-templated Another extracted example is MEF2B → B-cell, BCL6, CABIN1, DLBCL, In, Mutations, Recurrent. Use these groups to spot repeated connection types before inspecting the individual relationships.

MEF2B

Top relations

Gene ontology · 15
MEF2B → DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, histone deacetylase binding, muscle organ development, nucleus, positive regulation of transcription by RNA polymerase II, protein dimerization activity, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription by RNA polymerase II, transcription regulator complex, transcription, DNA-templated
related to Clinical relevance · 7
MEF2B → B-cell, BCL6, CABIN1, DLBCL, In, Mutations, Recurrent
related to Functions · 4
MEF2B → A/T-rich, Overexpression, SMHC, The MEF2
related to External links · 3
MEF2B → Medicine Medical Subject Headings, MeSH, National Library
Aliases · 1
MEF2B → BORCS8-MEF2B, LOC729991-MEF2B, MEF2B, MEF2BNB-MEF2B, BORCS8-MEF2B readthrough, RSRFR2
Available structures · 1
MEF2B → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1N6J, 1TQE
Databases · 1
MEF2B → NCBI: entry; OMA: entry
Ensembl · 1
MEF2B → ENSG00000064489
Entrez · 1
MEF2B → 4207
External IDs · 1
MEF2B → GeneCards: BORCS8-MEF2B

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene mef2 protein muscle binding factor transcription region external smooth family cabin1 human activity development regulation mrna mef2a mef2c mef2d

MEF2B relationships Subject–Predicate–Object triples

TTTA extracted 44 structured relationships around MEF2B. Examples in this analysis include MEF2B → Aliases → BORCS8-MEF2B, LOC729991-MEF2B, MEF2B, MEF2BNB-MEF2B, BORCS8-MEF2B readthrough, RSRFR2 and MEF2B → Available structures → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1N6J, 1TQE. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MEF2BAliasesBORCS8-MEF2B, LOC729991-MEF2B, MEF2B, MEF2BNB-MEF2B, BORCS8-MEF2B readthrough, RSRFR21.00infobox
MEF2BAvailable structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1N6J, 1TQE1.00infobox
MEF2BDatabasesNCBI: entry; OMA: entry1.00infobox
MEF2BEnsemblENSG000000644891.00infobox
MEF2BEntrez42071.00infobox
MEF2BExternal IDsGeneCards: BORCS8-MEF2B1.00infobox
MEF2BGene ontologyDNA-binding transcription factor activity1.00infobox
MEF2BGene ontologyRNA polymerase II cis-regulatory region sequence-specific DNA binding1.00infobox
MEF2BGene ontologyDNA binding1.00infobox
MEF2BGene ontologyDNA-binding transcription activator activity, RNA polymerase II-specific1.00infobox
MEF2BGene ontologyhistone deacetylase binding1.00infobox
MEF2BGene ontologyprotein dimerization activity1.00infobox
MEF2BGene ontologyRNA polymerase II transcription regulatory region sequence-specific DNA binding1.00infobox
MEF2BGene ontologyDNA-binding transcription factor activity, RNA polymerase II-specific1.00infobox
MEF2BGene ontologynucleus1.00infobox
MEF2BGene ontologytranscription regulator complex1.00infobox
MEF2BGene ontologymuscle organ development1.00infobox
MEF2BGene ontologyregulation of transcription, DNA-templated1.00infobox
MEF2BGene ontologytranscription, DNA-templated1.00infobox
MEF2BGene ontologytranscription by RNA polymerase II1.00infobox
MEF2BGene ontologypositive regulation of transcription by RNA polymerase II1.00infobox
MEF2BList of PDB id codesList of PDB id codes1N6J, 1TQE1.00infobox
MEF2BLocation (UCSC)n/a1.00infobox
MEF2BOrthologsOrthologsDatabasesNCBI: entry; OMA: entrySpeciesHumanMouseEntrez4207n/aEnsemblENSG00000064489n/aUniProtQ02080n/aRefSeq (mRNA)NM_005919n/aRefSeq (protein)NP_001139257 NP_00135421…1.00infobox
MEF2BPDBHuman UniProt search: PDBe RCSB1.00infobox
MEF2BRefSeq (mRNA)NM_0059191.00infobox
MEF2BRefSeq (protein)NP_001139257 NP_001354211 NP_005910.11.00infobox
MEF2BSpeciesHuman1.00infobox
MEF2BUniProtQ020801.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MEF2B bring nearby vocabulary together. In this analysis, examples include Mef2, Gene and Muscle. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MEF2B
    • Mef2
    • Gene
    • Muscle
    • Protein
    • Smooth
    • Activity
    • Cabin1
    • Family
    • Human
    • Mrna
    • Region
    • Regulation
  • mef2b
    • Mef2
    • Gene
    • Muscle
    • Protein
    • Smooth
    • Activity
    • Cabin1
    • Family
    • Human
    • Mrna
    • Region
    • Regulation
  • mef2a
    • Mef2c
    • Mef2d
    • Myocyte
    • Part
    • Transcription
    • Mef2b
  • diffuse large b-cell lymphoma
    • B-cell
    • Diffuse
    • Large
    • Mutations
    • Gene
    • Mef2b
  • mef2c
    • Mef2d
    • Myocyte
    • Part
    • Transcription
  • mef2d
    • Myocyte
    • Part
    • Transcription
  • cabin1
    • Mutations
    • Mef2b
    • Gene

Connections between topic areas Semantic bridges

For MEF2B, one of the stronger structural bridges in this analysis connects MEF2B with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MEF2BOverview · splits 6 ⟂ 4
MEF2BInteractions · splits 7 ⟂ 3

Map overview Semantic statistics

MEF2B

Nodes10
Edges9
Triples44
Avg. degree1.8
Density0.2
Components1

Source & methodology

TTTA analyzes the structure around MEF2B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MEF2B · EN edition · Analysis: TopicsToTalkAbout

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