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LIN28

Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene.

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Function

20 related topics

Overview

13 related topics

Structure

3 related topics

Key facts & relationships

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Aliases
LIN28A, CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A, lin-28 homolog A, Lin28a, LIN28A (gene), Lin-28 homolog A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CQF, 2LI8
Band
1p36.11 · 4|4 D2.3
Bgee
oocyte · secondary oocyte · sperm · gonad · buccal mucosa cell
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

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Overview

Structure

Function

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Map overview Semantic statistics

LIN28

Nodes40
Edges39
Triples124
Avg. degree1.95
Density0.05
Components1

How this topic connects Entity context

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LIN28

Top relations

Gene ontology · 43
LIN28 → cellular response to glucose stimulus, cytoplasm, cytoplasmic stress granule, cytosol, DNA binding, endoplasmic reticulum, G-quadruplex RNA binding, gene silencing, germ cell development, metal ion binding, miRNA binding, miRNA catabolic process, miRNA metabolic process, mRNA binding, negative regulation of glial cell differentiation, negative regulation of translation, nucleic acid binding, nucleolus, nucleus, P-body
Bgee · 19
LIN28 → Achilles tendon, buccal mucosa cell, embryo, epiblast, gonad, granulocyte, left testis, oocyte, otic placode, otic vesicle, primitive streak, right testis, secondary oocyte, somite, sperm, tail of embryo, testicle, yolk sac, zygote
RNA expression pattern · 19
LIN28 → Achilles tendon, buccal mucosa cell, embryo, epiblast, gonad, granulocyte, left testis, oocyte, otic placode, otic vesicle, primitive streak, right testis, secondary oocyte, somite, sperm, tail of embryo, testicle, yolk sac, zygote
related to Structure · 6
LIN28 → Lin28/let-7, Models, NMR, RNA, The, X-ray
related to Stem cell expression · 5
LIN28 → In, In Caenorhabditis, Lin28a, Lin28b, VPCs
related to Tissue regeneration · 5
LIN28 → Appropriate, Lin28a, Mice, The, While
related to Puberty · 4
LIN28 → Aberrant, LIN28B, Mutations, PI3K-mTOR
Band · 2
LIN28 → 1p36.11, 4|4 D2.3
Chr. · 2
LIN28 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
LIN28 → 133,746,152 bp, 26,429,728 bp

Important terminology Word statistics

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Important terminology

human stem gene cells bp chr band protein mouse homolog chromosome lin28a lin-28 mice embryonic expressed location let-7 puberty expression

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LIN28AliasesLIN28A, CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A, lin-28 homolog A, Lin28a, LIN28A (gene), Lin-28 homolog A1.00infobox
LIN28Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CQF, 2LI81.00infobox
LIN28Band1p36.111.00infobox
LIN28Band4|4 D2.31.00infobox
LIN28Bgeeoocyte1.00infobox
LIN28Bgeesecondary oocyte1.00infobox
LIN28Bgeesperm1.00infobox
LIN28Bgeegonad1.00infobox
LIN28Bgeebuccal mucosa cell1.00infobox
LIN28Bgeetesticle1.00infobox
LIN28Bgeeleft testis1.00infobox
LIN28Bgeeright testis1.00infobox
LIN28Bgeeembryo1.00infobox
LIN28BgeeAchilles tendon1.00infobox
LIN28Bgeeprimitive streak1.00infobox
LIN28Bgeetail of embryo1.00infobox
LIN28Bgeeepiblast1.00infobox
LIN28Bgeeotic placode1.00infobox
LIN28Bgeesomite1.00infobox
LIN28Bgeeotic vesicle1.00infobox
LIN28Bgeeyolk sac1.00infobox
LIN28Bgeezygote1.00infobox
LIN28Bgeegranulocyte1.00infobox
LIN28BioGPSMore reference expression data1.00infobox
LIN28Chr.Chromosome 1 (human)1.00infobox
LIN28Chr.Chromosome 4 (mouse)1.00infobox
LIN28DatabasesNCBI: entry; OMA: entry1.00infobox
LIN28End26,429,728 bp1.00infobox
LIN28End133,746,152 bp1.00infobox
LIN28EnsemblENSG000001319141.00infobox

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