Interleukin 3

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Explore the main themes, entities and connections around Interleukin 3. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Interleukin Immune system GM-CSF IL-5 Interleukin-3 receptor

27 related topics

Receptor

GM-CSF Hemopoietic system Basophils Eosinophils JAK2/STAT5

7 related topics

Immunological therapy

Myelodysplastic syndrome Aplastic anemia

2 related topics

Interactions

Interact IL3RA

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: IL3, interleukin 3, IL-3, MCGF, MULTI-CSF
Available structures: Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1JLI
Band: 5q31.1
Bgee: Achilles tendon · bone marrow · lymph node · appendix
BioGPS: More reference expression data
Chr.: Chromosome 5 (human)

Topics to explore

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Overview

Protein
Humans Human
Gene
Cytokine
Stem cells Stem cell
Progenitors Progenitor cell
Platelets Platelet
Isotype switching Immunoglobulin class switching

Function

Interleukin
Immune system
GM-CSF Granulocyte-macrophage colony-stimulating factor
IL-5 Interleukin 5
Interleukin-3 receptor
T cells T cell
IgG+ IgG
B cells B cell
Myelomonocytic cells Myelomonocyte
Macrophage
Granulocytes Granulocyte
Megakaryocytes Megakaryocyte
Multipotent hematopoietic stem cells Multipotent hematopoietic stem cell
Myeloid progenitor cells Myeloid progenitor cell
Lymphoid progenitor cells Lymphoid progenitor cell
Monocytes Monocyte
Dendritic cells Dendritic cell
Erythropoietin
IL-6 Interleukin 6
T cells
Autocrine
Paracrine
IL-2 Interleukin 2
IL-2 receptor
IL-1 Interleukin 1
Chromosome 5 Chromosome 5 (human)
GM-CSF

Receptor

GM-CSF Granulocyte-macrophage colony-stimulating factor receptor
Hemopoietic system Haematopoiesis
Basophils Basophil
Eosinophils Eosinophil
JAK2/STAT5 JAK-STAT signaling pathway
C‐myc Myc
Ras pathway Ras GTPase

Disease

Antigens Antigen

Immunological therapy

Interactions

Interact Protein-protein interaction
IL3RA

Advanced semantic analysis

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Map overview Semantic statistics

Nodes54

Edges53

Triples69

Avg. degree1.96

Density0.037037

Components1

How this topic connects Entity context

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Interleukin 3

Top relations

Gene ontology · 21

Interleukin 3 → cell-cell signaling, cytokine activity, cytokine-mediated signaling pathway, embryonic hemopoiesis, extracellular region, extracellular space, fever generation, growth factor activity, immune response, interleukin-1 receptor binding, interleukin-3 receptor binding, intracellular anatomical structure, MAPK cascade, nervous system development, peptidyl-tyrosine phosphorylation, positive regulation of cell population proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of tyrosine phosphorylation of STAT protein, protein tyrosine kinase activity, regulation of cytokine-mediated signaling pathway

related to Function · 8

Interleukin 3 → CSF, GM-CSF, However, IgG, IL-3, IL-5, In, Interleukin

related to Discovery · 6

Interleukin 3 → Ginsberg, IL-3, In, Interleukin, Sachs, The

Bgee · 4

Interleukin 3 → Achilles tendon, appendix, bone marrow, lymph node

RNA expression pattern · 4

Interleukin 3 → Achilles tendon, appendix, bone marrow, lymph node

related to Interactions · 2

Interleukin 3 → IL3RA, Interleukin

Aliases · 1

Interleukin 3 → IL3, interleukin 3, IL-3, MCGF, MULTI-CSF

Available structures · 1

Interleukin 3 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1JLI

Band · 1

Interleukin 3 → 5q31.1

BioGPS · 1

Interleukin 3 → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

il-3 cells cell interleukin factor also human gene receptor proliferation chromosome protein growth gm-csf cytokine function produced activated differentiation il3

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Interleukin 3	Aliases	IL3, interleukin 3, IL-3, MCGF, MULTI-CSF	1.00	infobox
Interleukin 3	Available structures	Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1JLI	1.00	infobox
Interleukin 3	Band	5q31.1	1.00	infobox
Interleukin 3	Bgee	Achilles tendon	1.00	infobox
Interleukin 3	Bgee	bone marrow	1.00	infobox
Interleukin 3	Bgee	lymph node	1.00	infobox
Interleukin 3	Bgee	appendix	1.00	infobox
Interleukin 3	BioGPS	More reference expression data	1.00	infobox
Interleukin 3	Chr.	Chromosome 5 (human)	1.00	infobox
Interleukin 3	Databases	NCBI: entry; OMA: entry	1.00	infobox
Interleukin 3	End	132,063,204 bp	1.00	infobox
Interleukin 3	Ensembl	ENSG00000164399	1.00	infobox
Interleukin 3	Entrez	3562	1.00	infobox
Interleukin 3	External IDs	OMIM: 147740; GeneCards: IL3	1.00	infobox
Interleukin 3	Gene location (Human)	Gene location (Human)Chr.Chromosome 5 (human)Band5q31.1Start132,060,655 bpEnd132,063,204 bp	1.00	infobox
Interleukin 3	Gene ontology	growth factor activity	1.00	infobox
Interleukin 3	Gene ontology	interleukin-3 receptor binding	1.00	infobox
Interleukin 3	Gene ontology	cytokine activity	1.00	infobox
Interleukin 3	Gene ontology	protein tyrosine kinase activity	1.00	infobox
Interleukin 3	Gene ontology	interleukin-1 receptor binding	1.00	infobox
Interleukin 3	Gene ontology	extracellular region	1.00	infobox
Interleukin 3	Gene ontology	intracellular anatomical structure	1.00	infobox
Interleukin 3	Gene ontology	extracellular space	1.00	infobox
Interleukin 3	Gene ontology	MAPK cascade	1.00	infobox
Interleukin 3	Gene ontology	embryonic hemopoiesis	1.00	infobox
Interleukin 3	Gene ontology	cell-cell signaling	1.00	infobox
Interleukin 3	Gene ontology	nervous system development	1.00	infobox
Interleukin 3	Gene ontology	positive regulation of peptidyl-tyrosine phosphorylation	1.00	infobox
Interleukin 3	Gene ontology	immune response	1.00	infobox
Interleukin 3	Gene ontology	peptidyl-tyrosine phosphorylation	1.00	infobox

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Connections between topic areas Semantic bridges

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