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IL3RA: Function, Interactions & Overview

Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene.

Language: English [EN]
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IL3RA topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around IL3RA.

Related topics
10
Source areas
3
Connected nodes
13
Extracted relationships
77
Related term clusters
11
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 8 topics
Interactions · 1 topics
Overview · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra, interleukin 3 receptor subunit alpha
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JZJ
Band
X;Y · 14 A1|14 7.08 cM
Bgee
right uterine tube · right hemisphere of cerebellum · left ovary · upper lobe of left lung · right ovary
BioGPS
More reference expression data
Chr.
X chromosome (human) · Chromosome 14 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How IL3RA connects Entity context

The extracted context around IL3RA shows recurring relationship patterns in the source. For example, IL3RA → apex of heart, body of uterus, embryo, epiblast, granulocyte, left ovary, left uterine tube, muscle layer of sigmoid colon, muscle of thigh, right hemisphere of cerebellum, right ovary, right uterine tube, seminiferous tubule, spermatocyte, stroma of bone marrow, sural nerve, thymus, upper lobe of left lung, yolk sac Another extracted example is IL3RA → cellular response to interleukin-3, cytokine binding, cytokine receptor activity, cytokine-mediated signaling pathway, external side of plasma membrane, integral component of membrane, interleukin-3 receptor activity, interleukin-3-mediated signaling pathway, intracellular anatomical structure, MAPK cascade, membrane, peptidyl-tyrosine phosphorylation, plasma membrane, protein tyrosine kinase activity, receptor complex. Use these groups to spot repeated connection types before inspecting the individual relationships.

IL3RA

Top relations

Bgee · 19
IL3RA → apex of heart, body of uterus, embryo, epiblast, granulocyte, left ovary, left uterine tube, muscle layer of sigmoid colon, muscle of thigh, right hemisphere of cerebellum, right ovary, right uterine tube, seminiferous tubule, spermatocyte, stroma of bone marrow, sural nerve, thymus, upper lobe of left lung, yolk sac
RNA expression pattern · 19
IL3RA → apex of heart, body of uterus, embryo, epiblast, granulocyte, left ovary, left uterine tube, muscle layer of sigmoid colon, muscle of thigh, right hemisphere of cerebellum, right ovary, right uterine tube, seminiferous tubule, spermatocyte, stroma of bone marrow, sural nerve, thymus, upper lobe of left lung, yolk sac
Gene ontology · 15
IL3RA → cellular response to interleukin-3, cytokine binding, cytokine receptor activity, cytokine-mediated signaling pathway, external side of plasma membrane, integral component of membrane, interleukin-3 receptor activity, interleukin-3-mediated signaling pathway, intracellular anatomical structure, MAPK cascade, membrane, peptidyl-tyrosine phosphorylation, plasma membrane, protein tyrosine kinase activity, receptor complex
Band · 2
IL3RA → 14 A1|14 7.08 cM, X;Y
Chr. · 2
IL3RA → Chromosome 14 (mouse), X chromosome (human)
End · 2
IL3RA → 1,382,689 bp, 8,123,488 bp
Aliases · 1
IL3RA → IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra, interleukin 3 receptor subunit alpha
Available structures · 1
IL3RA → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JZJ
BioGPS · 1
IL3RA → More reference expression data
Databases · 1
IL3RA → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp gene receptor chr band interleukin chromosome subunit alpha protein 123 external location cytokine cluster also mouse binding cd123

IL3RA relationships Subject–Predicate–Object triples

TTTA extracted 77 structured relationships around IL3RA. Examples in this analysis include IL3RA → Aliases → IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra, interleukin 3 receptor subunit alpha and IL3RA → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JZJ. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IL3RAAliasesIL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra, interleukin 3 receptor subunit alpha1.00infobox
IL3RAAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JZJ1.00infobox
IL3RABandX;Y1.00infobox
IL3RABand14 A1|14 7.08 cM1.00infobox
IL3RABgeeright uterine tube1.00infobox
IL3RABgeeright hemisphere of cerebellum1.00infobox
IL3RABgeeleft ovary1.00infobox
IL3RABgeeupper lobe of left lung1.00infobox
IL3RABgeeright ovary1.00infobox
IL3RABgeesural nerve1.00infobox
IL3RABgeeleft uterine tube1.00infobox
IL3RABgeemuscle layer of sigmoid colon1.00infobox
IL3RABgeebody of uterus1.00infobox
IL3RABgeeapex of heart1.00infobox
IL3RABgeegranulocyte1.00infobox
IL3RABgeeyolk sac1.00infobox
IL3RABgeestroma of bone marrow1.00infobox
IL3RABgeeembryo1.00infobox
IL3RABgeeseminiferous tubule1.00infobox
IL3RABgeethymus1.00infobox
IL3RABgeespermatocyte1.00infobox
IL3RABgeeepiblast1.00infobox
IL3RABgeemuscle of thigh1.00infobox
IL3RABioGPSMore reference expression data1.00infobox
IL3RAChr.X chromosome (human)1.00infobox
IL3RAChr.Chromosome 14 (mouse)1.00infobox
IL3RADatabasesNCBI: entry; OMA: entry1.00infobox
IL3RAEnd1,382,689 bp1.00infobox
IL3RAEnd8,123,488 bp1.00infobox
IL3RAEnsemblENSG000001852911.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around IL3RA bring nearby vocabulary together. In this analysis, examples include Interleukin, Human and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • IL3RA
    • Interleukin
    • Human
    • Gene
    • Receptor
    • Also
    • Cd123
    • Differentiation
    • External
    • Function
    • Search
    • Cluster
    • Location
  • il3ra
    • Interleukin
    • Human
    • Gene
    • Receptor
    • Also
    • Cd123
    • Differentiation
    • External
    • Function
    • Search
    • Cluster
    • Location
  • gene
    • Receptor
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Il3ra
    • Interleukin
    • A1
    • Cytokine
    • End
    • External
  • interleukin 3
    • Il3ra
    • Receptor
    • Alpha
    • Gene
    • Subunit
    • Also
    • Cd123
    • External
    • Function
    • Search
    • Specific
    • Human
  • interleukin 5
    • Il3ra
    • Receptor
    • Alpha
    • Gene
    • Subunit
    • Also
    • Cd123
    • External
    • Function
    • Search
    • Specific
    • Human
  • colony stimulating factor 2 receptor alpha
    • Factor
    • Stimulating
    • Receptor
    • Also
    • Cd123
    • Colony
    • Gene
    • Interleukin
    • Subunit
    • Cluster
    • Cytokine
    • Search
  • function
    • Search
    • Location
    • Chromosome
    • Bp
    • Chr
    • Gene
    • Il3ra
    • Interleukin
    • Receptor
    • Subunit
    • A1
    • Biological
  • cytokine
    • Gene
    • Receptor
    • Colony
    • End
    • External
    • Factor
    • Function
    • Mouse
    • Search
    • Specific
    • Stimulating
    • Location

Connections between topic areas Semantic bridges

For IL3RA, one of the stronger structural bridges in this analysis connects IL3RA with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IL3RA — Function · splits 5 ⟂ 9

Map overview Semantic statistics

IL3RA

Nodes14
Edges13
Triples77
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around IL3RA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IL3RA · EN edition · Analysis: TopicsToTalkAbout

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