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Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2).
Function, CR3 and CR4 & CR3 and CR4 for Disease Therapy
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cr3 ic3b cr4 cells binding phagocytosis shown cd18 cell complement receptor functions integrin cd11b human macrophage-1 antigen involved adhesion therapeutic
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IL-2 may cause a prolongation of the life of the immune cell while the presence of TNF-α induces apoptosis | instance of | phagocytosis and other cell-cell interactions in a variety of cells and circumstances.Upregulation of CR3 in the presence of certain factors | 0.80 | text |
| selective removal of the cell.A fully activated neutrophil may express on its membrane 200 | instance of | phagocytosis and other cell-cell interactions in a variety of cells and circumstances.Upregulation of CR3 in the presence of certain factors | 0.80 | text |
| 000 or more CR3 molecules.Absence of CR3 results in reduced binding | instance of | phagocytosis and other cell-cell interactions in a variety of cells and circumstances.Upregulation of CR3 in the presence of certain factors | 0.80 | text |
| ingestion of Mycobacterium tuberculosis in mice | instance of | phagocytosis and other cell-cell interactions in a variety of cells and circumstances.Upregulation of CR3 in the presence of certain factors | 0.80 | text |
| Macrophage-1 antigen | related to Function | Macrophage-1 | 0.60 | section |
| Macrophage-1 antigen | related to Function | CR3 | 0.60 | section |
| Macrophage-1 antigen | related to Function | CD11b/CD18 | 0.60 | section |
| Macrophage-1 antigen | related to Function | NK | 0.60 | section |
| Macrophage-1 antigen | related to Function | C3b | 0.60 | section |
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