Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

IFNA2: Clinical significance, Gene and protein & Synthesis

Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

IFNA2 topic overview

The analysis highlights Clinical significance, Gene and protein and Synthesis as prominent areas in the source structure around IFNA2.

Related topics
69
Source areas
6
Connected nodes
75
Extracted relationships
106
Concept neighborhoods
27
Bridge connections
75

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 20 topics
Gene and protein · 19 topics
Overview · 15 topics
Synthesis · 7 topics
Function · 4 topics
Mechanism of action · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon, alpha 2, interferon alpha 2, IFN-alpha-2, leIF A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RH2, 3S9D, 1ITF, 2LAG, 4YPG, 2KZ1, 2HYM, 2LMS, 3SE3, 4Z5R
Band
9p21.3 · 4 C4|4 42.02 cM
Bgee
testicle · corpus callosum · putamen · apex of heart · Achilles tendon
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene and protein

Synthesis

Mechanism of action

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IFNA2 connects Entity context

The extracted context around IFNA2 shows recurring relationship patterns in the source. For example, IFNA2 → adaptive immune response, apoptotic process, B cell differentiation, B cell proliferation, blood coagulation, cell surface receptor signaling pathway, cell-cell signaling, collagen-containing extracellular matrix, cytokine activity, cytokine receptor binding, cytokine-mediated signaling pathway, defense response, defense response to virus, extracellular region, extracellular space, humoral immune response, inflammatory response, innate immune response, natural killer cell activation involved in immune response, negative regulation of gene expression Another extracted example is IFNA2 → A-B, According, Arg23Lys, AU-rich, C-terminal, H57R, Helices, His34Arg, IFN, IFNα, IFNα2, N-terminal, R46K, RNA, Several, The, Upstream, UTR. Use these groups to spot repeated connection types before inspecting the individual relationships.

IFNA2

Top relations

Gene ontology · 34
IFNA2 → adaptive immune response, apoptotic process, B cell differentiation, B cell proliferation, blood coagulation, cell surface receptor signaling pathway, cell-cell signaling, collagen-containing extracellular matrix, cytokine activity, cytokine receptor binding, cytokine-mediated signaling pathway, defense response, defense response to virus, extracellular region, extracellular space, humoral immune response, inflammatory response, innate immune response, natural killer cell activation involved in immune response, negative regulation of gene expression
related to Gene and protein · 18
IFNA2 → A-B, According, Arg23Lys, AU-rich, C-terminal, H57R, Helices, His34Arg, IFN, IFNα, IFNα2, N-terminal, R46K, RNA, Several, The, Upstream, UTR
Bgee · 11
IFNA2 → Achilles tendon, amygdala, apex of heart, caudate nucleus, corpus callosum, hippocampus proper, lacrimal gland, mesencephalon, putamen, temporal lobe, testicle
RNA expression pattern · 11
IFNA2 → Achilles tendon, amygdala, apex of heart, caudate nucleus, corpus callosum, hippocampus proper, lacrimal gland, mesencephalon, putamen, temporal lobe, testicle
Band · 2
IFNA2 → 4 C4|4 42.02 cM, 9p21.3
Chr. · 2
IFNA2 → Chromosome 4 (mouse), Chromosome 9 (human)
End · 2
IFNA2 → 21,385,398 bp, 88,602,149 bp
Aliases · 1
IFNA2 → IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon, alpha 2, interferon alpha 2, IFN-alpha-2, leIF A
Available structures · 1
IFNA2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RH2, 3S9D, 1ITF, 2LAG, 4YPG, 2KZ1, 2HYM, 2LMS, 3SE3, 4Z5R
BioGPS · 1
IFNA2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

type ifns ifnα2 cells viral gene ifn human interferon protein bp also iii immune chr band isgs infected several known

IFNA2 relationships Subject–Predicate–Object triples

TTTA extracted 106 structured relationships around IFNA2. Examples in this analysis include IFNA2 → Aliases → IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon, alpha 2, interferon alpha 2, IFN-alpha-2, leIF A and IFNA2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RH2, 3S9D, 1ITF, 2LAG, 4YPG, 2KZ1, 2HYM, 2LMS, 3SE3, 4Z5R. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IFNA2AliasesIFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2, interferon, alpha 2, interferon alpha 2, IFN-alpha-2, leIF A1.00infobox
IFNA2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RH2, 3S9D, 1ITF, 2LAG, 4YPG, 2KZ1, 2HYM, 2LMS, 3SE3, 4Z5R1.00infobox
IFNA2Band9p21.31.00infobox
IFNA2Band4 C4|4 42.02 cM1.00infobox
IFNA2Bgeetesticle1.00infobox
IFNA2Bgeecorpus callosum1.00infobox
IFNA2Bgeeputamen1.00infobox
IFNA2Bgeeapex of heart1.00infobox
IFNA2BgeeAchilles tendon1.00infobox
IFNA2Bgeehippocampus proper1.00infobox
IFNA2Bgeecaudate nucleus1.00infobox
IFNA2Bgeetemporal lobe1.00infobox
IFNA2Bgeeamygdala1.00infobox
IFNA2Bgeemesencephalon1.00infobox
IFNA2Bgeelacrimal gland1.00infobox
IFNA2BioGPSMore reference expression data1.00infobox
IFNA2Chr.Chromosome 9 (human)1.00infobox
IFNA2Chr.Chromosome 4 (mouse)1.00infobox
IFNA2DatabasesNCBI: entry; OMA: entry1.00infobox
IFNA2End21,385,398 bp1.00infobox
IFNA2End88,602,149 bp1.00infobox
IFNA2EnsemblENSG000001883791.00infobox
IFNA2Entrez34401.00infobox
IFNA2External IDsOMIM: 147562; MGI: 107666; GeneCards: IFNA21.00infobox
IFNA2Gene location (Human)Gene location (Human)Chr.Chromosome 9 (human)Band9p21.3Start21,384,255 bpEnd21,385,398 bp1.00infobox
IFNA2Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 4 (mouse)Band4 C4|4 42.02 cMStart88,601,118 bpEnd88,602,149 bp1.00infobox
IFNA2Gene ontologycytokine activity1.00infobox
IFNA2Gene ontologytype I interferon receptor binding1.00infobox
IFNA2Gene ontologyprotein binding1.00infobox
IFNA2Gene ontologycytokine receptor binding1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IFNA2 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Interferon. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • interferon alpha
    • Gene
    • Ifna2
    • Human
    • Protein
    • Chromosome
    • 2b
    • Bp
    • Chr
    • Action
    • Family
    • Type
    • Antiviral
  • cells
    • Infected
    • Type
    • Ifn
    • Ifns
    • System
    • Also
    • Viral
    • Immune
    • Specific
    • Activation
    • Activity
    • Known
  • virus
    • Cell
    • Cellular
    • Immune
    • Infected
    • Viral
    • Protein
    • Band
    • Chromosome
    • End
    • Infections
    • Specific
    • System
  • interferon type i
    • Gene
    • Ifna2
    • Human
    • Protein
    • Chromosome
    • Activity
    • 2b
    • Bp
    • Chr
    • Activation
    • Known
    • Infections
  • interferon type ii
    • Gene
    • Ifna2
    • Human
    • Protein
    • Chromosome
    • Activity
    • 2b
    • Bp
    • Chr
    • Activation
    • Known
    • Infections
  • interferon type iii
    • Gene
    • Ifna2
    • Human
    • Protein
    • Chromosome
    • Activity
    • 2b
    • Bp
    • Chr
    • Type
    • Action
    • Activation
  • epithelial cells
    • Infected
    • Type
    • Ifn
    • Ifns
    • System
    • Also
    • Viral
    • Immune
    • Specific
    • Activation
    • Activity
    • Known
  • interferon alfa 2a
    • Gene
    • Ifna2
    • Human
    • Protein
    • Chromosome
    • 2b
    • Bp
    • Chr
    • Action
    • Family
    • Type
    • Antiviral

Connections between topic areas Semantic bridges

For IFNA2, one of the stronger structural bridges in this analysis connects IFNA2 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IFNA2Clinical significance · splits 55 ⟂ 21
IFNA2Gene and protein · splits 56 ⟂ 20
IFNA2Overview · splits 60 ⟂ 16
IFNA2Synthesis · splits 68 ⟂ 8
IFNA2Mechanism of action · splits 71 ⟂ 5
IFNA2Function · splits 71 ⟂ 5

Map overview Semantic statistics

IFNA2

Nodes76
Edges75
Triples106
Avg. degree1.97
Density0.026316
Components1

Source & methodology

TTTA analyzes the structure around IFNA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Gene and protein & Synthesis, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IFNA2 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.