HMGA1

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Explore the main themes, entities and connections around HMGA1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Heterochromatin Integration AT-hooks Motif Cross-linking

12 related topics

Interactions

Interact CEBPB Sp1 transcription factor

3 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: HMGA1, HMG-R, HMGA1A, HMGIY, high mobility group AT-hook 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EZD, 2EZE, 2EZF, 2EZG
Band: 6p21.31 · 17 A3.3|17 14.5 cM
Bgee: cartilage tissue · embryo · mucosa of pharynx · ganglionic eminence · skin of abdomen
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 17 (mouse)

Topics to explore

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Overview

Function

Heterochromatin
Integration Retroviral integration
AT-hooks AT-hook
Motif Sequence motif
Cross-linking Cross-link
C-terminal
HMG High mobility group
FRAP Fluorescence recovery after photobleaching
Post-transcriptional modifications Post-transcriptional modification
Posttranslational modifications Posttranslational modification
Diabetic
Insulin receptor

Interactions

Interact Protein-protein interaction
CEBPB
Sp1 transcription factor

Advanced semantic analysis

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Map overview Semantic statistics

Nodes21

Edges20

Triples130

Avg. degree1.9

Density0.095238

Components1

How this topic connects Entity context

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HMGA1

Top relations

Gene ontology · 44

HMGA1 → 5'-deoxyribose-5-phosphate lyase activity, base-excision repair, chromatin, chromatin binding, chromosome, cis-regulatory region sequence-specific DNA binding, cytosol, DNA binding, DNA unwinding involved in DNA replication, DNA-(apurinic or apyrimidinic site) endonuclease activity, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, enzyme binding, establishment of integrated proviral latency, focal adhesion, minor groove of adenine-thymine-rich DNA binding, negative regulation of cell population proliferation, negative regulation of transcription, DNA-templated, nuclear receptor coactivator activity

Bgee · 18

HMGA1 → appendix, cartilage tissue, embryo, epiblast, ganglionic eminence, genital tubercle, lip, mucosa of pharynx, mucosa of transverse colon, nipple, secondary oocyte, skin of abdomen, skin of leg, tail of embryo, thymus, ventricular zone, yolk sac, zygote

RNA expression pattern · 18

related to External links · 13

HMGA1 → High, HMG-I/HMG-Y, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Overview, P17096, PDB, PDBe-KB, This, UniProt, United States National Library

related to Function · 11

HMGA1 → Arg-Gly-Arg-Pro, AT-hook, AT-hooks, C-terminal, DNA, HMG, HMGA, HMGB, HMGN, RGRP, This

Band · 2

HMGA1 → 17 A3.3|17 14.5 cM, 6p21.31

Chr. · 2

HMGA1 → Chromosome 17 (mouse), Chromosome 6 (human)

End · 2

HMGA1 → 27,782,648 bp, 34,246,231 bp

related to Interactions · 2

HMGA1 → CEBPB, Sp1

Aliases · 1

HMGA1 → HMGA1, HMG-R, HMGA1A, HMGIY, high mobility group AT-hook 1

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene human chr chromosome band protein dna heterochromatin proteins group location at-hook hmga chromatin also mouse hmga1a high tail

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
HMGA1	Aliases	HMGA1, HMG-R, HMGA1A, HMGIY, high mobility group AT-hook 1	1.00	infobox
HMGA1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EZD, 2EZE, 2EZF, 2EZG	1.00	infobox
HMGA1	Band	6p21.31	1.00	infobox
HMGA1	Band	17 A3.3\|17 14.5 cM	1.00	infobox
HMGA1	Bgee	cartilage tissue	1.00	infobox
HMGA1	Bgee	embryo	1.00	infobox
HMGA1	Bgee	mucosa of pharynx	1.00	infobox
HMGA1	Bgee	ganglionic eminence	1.00	infobox
HMGA1	Bgee	skin of abdomen	1.00	infobox
HMGA1	Bgee	thymus	1.00	infobox
HMGA1	Bgee	mucosa of transverse colon	1.00	infobox
HMGA1	Bgee	skin of leg	1.00	infobox
HMGA1	Bgee	nipple	1.00	infobox
HMGA1	Bgee	appendix	1.00	infobox
HMGA1	Bgee	epiblast	1.00	infobox
HMGA1	Bgee	tail of embryo	1.00	infobox
HMGA1	Bgee	yolk sac	1.00	infobox
HMGA1	Bgee	genital tubercle	1.00	infobox
HMGA1	Bgee	secondary oocyte	1.00	infobox
HMGA1	Bgee	zygote	1.00	infobox
HMGA1	Bgee	lip	1.00	infobox
HMGA1	Bgee	ventricular zone	1.00	infobox
HMGA1	BioGPS	More reference expression data	1.00	infobox
HMGA1	Chr.	Chromosome 6 (human)	1.00	infobox
HMGA1	Chr.	Chromosome 17 (mouse)	1.00	infobox
HMGA1	Databases	NCBI: entry; OMA: entry	1.00	infobox
HMGA1	End	34,246,231 bp	1.00	infobox
HMGA1	End	27,782,648 bp	1.00	infobox
HMGA1	Ensembl	ENSG00000137309	1.00	infobox
HMGA1	Entrez	3159	1.00	infobox

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Min side: 3