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Hepatic encephalopathy

Hepatic encephalopathy (HE) is an altered level of consciousness as a result of liver failure. Its onset may be gradual or sudden. Other symptoms may include movement problems, changes in mood, or changes in personality. In the advanced stages, it can result in a coma.

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Causes
Liver failure
Complications
hepatic coma.
Diagnostic method
Based on symptoms after ruling out other possible causes
Differential diagnosis
Wernicke–Korsakoff syndrome, delirium tremens, hypoglycemia, subdural hematoma, hyponatremia
Frequency
Affects >40% with cirrhosis
Other names
Portosystemic encephalopathy, hepatic coma, coma hepaticum

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Overview

Signs and symptoms

Causes

Pathogenesis

Diagnosis

Treatment

Epidemiology and prognosis

History

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Map overview Semantic statistics

Hepatic encephalopathy

Nodes159
Edges158
Triples113
Avg. degree1.99
Density0.012579
Components1

How this topic connects Entity context

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Hepatic encephalopathy

Top relations

related to Investigations · 17
Hepatic encephalopathy → CT, EEG, Electroencephalography, HE, However, Hz, II, III, IV, MRI, Other, Rarer, Serum, The, To, Wernicke's, Wilson's
related to history · 13
Hepatic encephalopathy → BCE, Celsus, Cos, Galen, Giovanni Battista Morgagni, Hippocrates, In, London, Many, Professor Dame Sheila Sherlock, Royal Free Hospital, Royal Postgraduate Medical School, The
related to Pathogenesis · 10
Hepatic encephalopathy → Astrocytes, Despite, GABA, In, NH3, Nitrogenous, Other, The, There, This
related to Antibiotics · 9
Hepatic encephalopathy → Due, It, Later, Metronidazole, Neomycin, Rifaximin, The, This, When
related to Epidemiology and prognosis · 9
Hepatic encephalopathy → Child, Historically, In, King's College Criteria, Once, Pugh, The, Together, Wilson's
related to Lactulose/lactitol · 9
Hepatic encephalopathy → Doses, In, Lactulose, More, NH4, Side, The, They, This
has treatment · 8
Hepatic encephalopathy → Hepatic, If, Placement, The, This, Those, TIPS, Transferring
related to Signs and symptoms · 8
Hepatic encephalopathy → Babinski, Coma, EEG, In, It, More, The, There
has cause · 6
Hepatic encephalopathy → Hepatic, In, More, This, TIPS, TIPS-related
related to L-Ornithine and L-aspartate · 5
Hepatic encephalopathy → L-aspartate, L-ornithine, LOLA, The, Very

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Important terminology

encephalopathy hepatic may liver lactulose disease ammonia symptoms failure causes coma treatment levels brain used people level cirrhosis acute severe

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Hepatic encephalopathyCausesLiver failure1.00infobox
Hepatic encephalopathyComplicationshepatic coma.1.00infobox
Hepatic encephalopathyDiagnostic methodBased on symptoms after ruling out other possible causes1.00infobox
Hepatic encephalopathyDifferential diagnosisWernicke–Korsakoff syndrome, delirium tremens, hypoglycemia, subdural hematoma, hyponatremia1.00infobox
Hepatic encephalopathyFrequencyAffects >40% with cirrhosis1.00infobox
Hepatic encephalopathyOther namesPortosystemic encephalopathy, hepatic coma, coma hepaticum1.00infobox
Hepatic encephalopathyPrognosisAverage life expectancy less than a year in those with severe disease1.00infobox
Hepatic encephalopathyRisk factorsInfections, GI bleeding, constipation, electrolyte problems, certain medications1.00infobox
Hepatic encephalopathySpecialtyGastroenterology1.00infobox
Hepatic encephalopathySymptomsAltered level of consciousness, mood changes, personality changes, movement problems slurred speech, Sleep problems, Anxiety or irritability, Muscle twitches (myoclonus), Diffic…1.00infobox
Hepatic encephalopathyTreatmentSupportive care, treating triggers, lactulose, liver transplant1.00infobox
Hepatic encephalopathyTypesAcute, recurrent, persistent1.00infobox
Hepatic encephalopathyis aclinical one0.90text

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