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EF-G

EF-G (elongation factor G, historically known as translocase) is a prokaryotic elongation factor involved in mRNA translation. As a GTPase, EF-G catalyzes the movement (translocation) of transfer RNA (tRNA) and messenger RNA (mRNA) through the ribosome.

Evolution, Clinical significance & Structure

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Key facts & relationships

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Alt. names
Elongation factor G, EF-G
BRENDA
enzyme data
EC no.
3.6.5.3
ExPASy
NiceZyme view
KEGG
enzyme entry
MetaCyc
metabolic pathway

Topics to explore

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Overview

Structure

Function in protein elongation

Function in protein termination

Clinical significance

Evolution

Advanced semantic analysis

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Map overview Semantic statistics

EF-G

Nodes45
Edges44
Triples90
Avg. degree1.96
Density0.044444
Components1

How this topic connects Entity context

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EF-G

Top relations

related to Further reading · 18
EF-G → Andrei, Anna, Carbone, Christine, December, Demo, EM, Gabriel, Gamper, GTP, Hou, Howard, Korostelev, Loveland, Nature Communications, PMC, Time-resolved, Ya-Ming
related to Structure · 18
EF-G → Domain, Domain IV, Domains, Domains III, EF-Tu, Encoded, G-domain, GTP, However, II, IV, N-terminal, POST, PRE, Super-domain, Super-domain II, The, Throughout
related to Function in protein termination · 17
EF-G → B2a/B2b, Class, Class II, GTP, GTP-dependent, IF3, In, Initiation Factor, Protein, RF1, RF2, RF3, RF3/prfC, Ribosome, RRF, The, This
related to Function in protein elongation · 12
EF-G → A/P, As, EF-G-GTP, GDP, GTP, GTP-bound, GTPase, In, P/E, PTC, The, This
related to Evolution · 10
EF-G → Bdellovibrionota, Elongation, However, In, Myxococcota, Planctomycetota, Proteobacteria, Spirochaetota, The, Thermodesulfobacteriota
related to Clinical significance · 3
EF-G → Dityromycin, For, GE82832
Alt. names · 1
EF-G → Elongation factor G, EF-G
BRENDA · 1
EF-G → enzyme data
EC no. · 1
EF-G → 3.6.5.3
ExPASy · 1
EF-G → NiceZyme view

Important terminology Word statistics

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Important terminology

ribosome elongation trna factor translocation ribosomal mrna gtp gtpase binding protein site large bacteria subunit domains super-domain release factors domain

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
EF-GAlt. namesElongation factor G, EF-G1.00infobox
EF-GBRENDAenzyme data1.00infobox
EF-GEC no.3.6.5.31.00infobox
EF-GExPASyNiceZyme view1.00infobox
EF-GKEGGenzyme entry1.00infobox
EF-GMetaCycmetabolic pathway1.00infobox
EF-GNCBIproteins1.00infobox
EF-GPDB structuresRCSB PDB PDBe PDBsum1.00infobox
EF-GPMCarticles1.00infobox
EF-GPubMedarticles1.00infobox
EF-GRheareactions1.00infobox
EF-GSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

Related concept clusters Concept neighborhoods

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    Min side: 3
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