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Whole genome sequencing

Whole genome sequencing (WGS), also known as full genome sequencing or just genome sequencing, is the process of determining the entirety of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast.

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Overview

History

Experimental details

Commercialization

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Applications

Ethical concerns

Public human genome sequences

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Whole genome sequencing

Nodes156
Edges155
Triples64
Avg. degree1.99
Density0.012821
Components1

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Whole genome sequencing

Top relations

related to Diagnostic use · 19
Whole genome sequencing → Allan Mayer, By, David Dimmock, Dr, Drs Jacob, Geneticist Dr, His, Howard Jacob, IBD, Illumina, In, July, Lead, MCW, Milwaukee Children's Hospital, The, This, Worthey, XIAP
related to Newborn screening · 11
Whole genome sequencing → As, BabySeq, BabySeq Project, BabySeq2, DNA, Green, In, Lancet, NIH, UK, Whole
related to Ethical concerns · 7
Whole genome sequencing → February, Illumina's CEO, Jay Flatley, On, Some, The, This
related to Rare variant association study · 6
Whole genome sequencing → MAF, Meta-analysis, Single-variant, SNP, Some, Whole
related to Mutation frequencies · 5
Whole genome sequencing → An, In, Only, The, Whole
related to Oncology · 5
Whole genome sequencing → Deep, DNA, In, It, This
related to Genomic coverage · 1
Whole genome sequencing → In

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Important terminology

genome sequencing whole dna human first sequence genetic sequenced genomes full citation needed mutation rare genomics data information use also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Amoeba dubiainstance ofboth unicellular and multicellular0.80text
humansinstance ofboth unicellular and multicellular0.80text
bacterial artificial chromosomesinstance ofEukaryotic genomes are sequenced by several methods including Shotgun sequencing of short DNA fragments and sequencing of larger DNA clones from DNA libraries0.80text
Illumina dye sequencinginstance ofsequencing technologies0.80text
pyrosequencinginstance ofsequencing technologies0.80text
and SMRT sequencinginstance ofsequencing technologies0.80text
genetic discriminationinstance ofgenetic testing has potential downsides0.80text
loss of anonymityinstance ofgenetic testing has potential downsides0.80text
and psychological impacts such as discovery of non-paternity.Some ethicists insist that the privacy of individuals undergoing genetic testing must be protectedinstance ofgenetic testing has potential downsides0.80text
and is of particular concern when minors undergo genetic testinginstance ofgenetic testing has potential downsides0.80text
Whole genome sequencingrelated to Diagnostic useIn0.60section
Whole genome sequencingrelated to Diagnostic useIllumina0.60section

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