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Gelsemine

Gelsemine (C20H22N2O2) is an indole alkaloid isolated from flowering plants of the genus Gelsemium, a plant native to the subtropical and tropical Americas, and southeast Asia, and is a highly toxic compound that acts as a paralytic, exposure to which can result in death. It has generally potent activity as an agonist of the mammalian glycine receptor…

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Toxicity and toxicology

18 related topics

Chemistry

15 related topics

Popular culture

5 related topics

Summary of biological activities

8 related topics

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3D model (JSmol)
Interactive image
ATC code
none
CAS Number
509-15-9
ChemSpider
4536577
Formula
C20H22N2O2
Molar mass
322.408 g·mol−1

Topics to explore

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Overview

Natural sources

Chemistry

Summary of biological activities

Toxicity and toxicology

Chemical synthesis

Potential medical applications

Popular culture

Advanced semantic analysis

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Map overview Semantic statistics

Gelsemine

Nodes70
Edges69
Triples118
Avg. degree1.97
Density0.028571
Components1

How this topic connects Entity context

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Gelsemine

Top relations

related to Chemical synthesis · 23
Gelsemine → Additional, Alder, Although, Aubé, China, Danishefsky, Diels, Eight, Fleming, Fukuyama, Hart, Johnson, Overman, Pearson, Penkett, Qin, Qiu, Simpkins, Speckamp's, Stork
related to Popular culture · 19
Gelsemine → Agatha Christie, Agatha Christie's Poirot, Cards, Claire, Claire Underwood, In House, It, ITV, Jane Davis, Later, Madame Olivier, Mr, Olivier, Patricia Hodge, Paynter, Stephen Paynter, Steven Pacey, The Big Four, Tom Yates
related to Natural sources · 17
Gelsemine → Ait, All, Americas, Asia, Belize, Benth, Carolina, China, East Asia, Europe, Gelsemiaceae, Gelsemium, Guatemala, Honduras, It, Mexico, The
related to history · 12
Gelsemine → American Chemical Society, Arthur Conan Doyle, Assay, British Medical Journal, December, Division, England, Gelsemium, Gelsimium, On, Pharmaceutical Chemistry, Sayre
related to Chemistry · 9
Gelsemine → Ait, C20H22N2O2, Chakrabarti, Conroy, It, Its, NMR, The, X-ray
related to Modern medical utility · 7
Gelsemine → Based, Diazepam, Gelsemium, In, Pharmacological, Recent, The
has treatment · 4
Gelsemine → Activated, Benzodiazepine, Electrolyte, In
related to Mechanisms of action · 4
Gelsemine → GlyR, These, This, When
related to Summary of biological activities · 4
Gelsemine → Full, In, It, Noted
related to Traditional medical uses · 3
Gelsemine → Applications, Gelsemium, Preparations

Important terminology Word statistics

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Important terminology

alkaloids gelsemium glycine treatment potential activities plant oxidative sempervirens research stress effects natural chemical synthesis indole americas agonist used needed

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Gelsemine3D model (JSmol)Interactive image1.00infobox
GelsemineATC codenone1.00infobox
GelsemineCAS Number509-15-91.00infobox
GelsemineChemSpider45365771.00infobox
GelsemineFormulaC20H22N2O21.00infobox
GelsemineMolar mass322.408 g·mol−11.00infobox
GelseminePubChem CID2790571.00infobox
GelsemineUNII5Y13A78Z721.00infobox
the increase in allopregnanolone production associated with gelsemine poisoninginstance ofresulting in a counteraction of some downstream effects0.80text
Fleminginstance ofAdditional synthetic approaches were discussed by notable scientists0.80text
Storkinstance ofAdditional synthetic approaches were discussed by notable scientists0.80text
Penkettinstance ofAdditional synthetic approaches were discussed by notable scientists0.80text

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