Histamine H2 receptor

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Explore the main themes, entities and connections around Histamine H2 receptor. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Tissue distribution

Parietal cells (oxyntic cells)Vascular smooth muscle Neutrophils Mast cells Heart

15 related topics

Physiological responses

Gastric acid Peptic ulcer disease GERD Smooth muscle Antibody

12 related topics

Function

Mast cells Enterochromaffin-like cells Neurons Rhodopsin G protein-coupled receptors

6 related topics

Overview

Histamine Adenylate cyclase Gs alpha subunit CAMP Protein kinase A

6 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: HRH2, H2R, histamine receptor H2, HH2R
Band: 5q35.2 · 13 B1|13 28.4 cM
Bgee: monocyte · blood · granulocyte · left ventricle · apex of heart
BioGPS: More reference expression data
Chr.: Chromosome 5 (human) · Chromosome 13 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Function

Mast cells Mast cell
Enterochromaffin-like cells
Neurons Neuron
Rhodopsin
G protein-coupled receptors G protein-coupled receptor
Integral membrane protein

Tissue distribution

Parietal cells (oxyntic cells) Parietal cells
Vascular smooth muscle
Neutrophils
Mast cells
Heart
Genitourinary system
Uterus
Bladder
Central nervous system
Caudate Caudate nucleus
Putamen
Cerebral cortex
Hippocampal formation
Dentate nucleus
Cerebellum

Physiological responses

Advanced semantic analysis

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Map overview Semantic statistics

Nodes44

Edges43

Triples102

Avg. degree1.95

Density0.045455

Components1

How this topic connects Entity context

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Histamine H2 receptor

Top relations

Gene ontology · 27

Histamine H2 receptor → chemical synaptic transmission, dendrite, digestive tract development, epithelial cell morphogenesis, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G protein-coupled serotonin receptor activity, G protein-coupled serotonin receptor signaling pathway, gastric acid secretion, gastrin-induced gastric acid secretion, gland development, histamine receptor activity, histamine-induced gastric acid secretion, immune response, integral component of membrane, integral component of plasma membrane, membrane, memory, neurotransmitter receptor activity

Bgee · 18

Histamine H2 receptor → apex of heart, blood, body of stomach, caudate nucleus, decidua, dentate gyrus of hippocampal formation granule cell, epithelium of stomach, granulocyte, internal carotid artery, left ventricle, monocyte, mucous cell of stomach, myocardium of left ventricle, neuron, prefrontal cortex, primary visual cortex, putamen, superior frontal gyrus

RNA expression pattern · 18

related to Physiological responses · 16

Histamine H2 receptor → Activation, COPD, Experimental, GERD, H2, Inhibit, Inhibition, MLC, MLCK, MLCP, PKA, Smooth, Stimulation, T-cell, Target, The

related to Tissue distribution · 3

Histamine H2 receptor → Gastric, Histamine H2, Vascular

Band · 2

Histamine H2 receptor → 13 B1|13 28.4 cM, 5q35.2

Chr. · 2

Histamine H2 receptor → Chromosome 13 (mouse), Chromosome 5 (human)

End · 2

Histamine H2 receptor → 175,710,756 bp, 54,390,199 bp

Aliases · 1

Histamine H2 receptor → HRH2, H2R, histamine receptor H2, HH2R

BioGPS · 1

Histamine H2 receptor → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

histamine h2 receptor bp receptors chr human band chromosome secretion protein activity gene location external activation hrh2 mouse pka gastric

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Histamine H2 receptor	Aliases	HRH2, H2R, histamine receptor H2, HH2R	1.00	infobox
Histamine H2 receptor	Band	5q35.2	1.00	infobox
Histamine H2 receptor	Band	13 B1\|13 28.4 cM	1.00	infobox
Histamine H2 receptor	Bgee	monocyte	1.00	infobox
Histamine H2 receptor	Bgee	blood	1.00	infobox
Histamine H2 receptor	Bgee	granulocyte	1.00	infobox
Histamine H2 receptor	Bgee	left ventricle	1.00	infobox
Histamine H2 receptor	Bgee	apex of heart	1.00	infobox
Histamine H2 receptor	Bgee	body of stomach	1.00	infobox
Histamine H2 receptor	Bgee	putamen	1.00	infobox
Histamine H2 receptor	Bgee	caudate nucleus	1.00	infobox
Histamine H2 receptor	Bgee	myocardium of left ventricle	1.00	infobox
Histamine H2 receptor	Bgee	prefrontal cortex	1.00	infobox
Histamine H2 receptor	Bgee	internal carotid artery	1.00	infobox
Histamine H2 receptor	Bgee	epithelium of stomach	1.00	infobox
Histamine H2 receptor	Bgee	mucous cell of stomach	1.00	infobox
Histamine H2 receptor	Bgee	primary visual cortex	1.00	infobox
Histamine H2 receptor	Bgee	superior frontal gyrus	1.00	infobox
Histamine H2 receptor	Bgee	neuron	1.00	infobox
Histamine H2 receptor	Bgee	decidua	1.00	infobox
Histamine H2 receptor	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Histamine H2 receptor	BioGPS	More reference expression data	1.00	infobox
Histamine H2 receptor	Chr.	Chromosome 5 (human)	1.00	infobox
Histamine H2 receptor	Chr.	Chromosome 13 (mouse)	1.00	infobox
Histamine H2 receptor	Databases	NCBI: entry; OMA: entry	1.00	infobox
Histamine H2 receptor	End	175,710,756 bp	1.00	infobox
Histamine H2 receptor	End	54,390,199 bp	1.00	infobox
Histamine H2 receptor	Ensembl	ENSG00000113749	1.00	infobox
Histamine H2 receptor	Entrez	3274	1.00	infobox
Histamine H2 receptor	External IDs	OMIM: 142703; MGI: 108482; GeneCards: HRH2	1.00	infobox

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