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FGL1: Function, Clinical significance & Overview

Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FGL-1 is encoded by the FGL1 gene. It is classified as a hepatokine. Four splice variants exist for this gene.

Language: English [EN]
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FGL1 topic overview

The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around FGL1.

Related topics
20
Source areas
3
Connected nodes
23
Extracted relationships
60
Concept neighborhoods
13
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 14 topics
Overview · 5 topics
Clinical significance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1, fibrinogen like 1, HPS
Band
8p22 · 8|8 A4
Bgee
right lobe of liver · body of pancreas · sperm · islet of Langerhans · buccal mucosa cell
BioGPS
More reference expression data
Chr.
Chromosome 8 (human) · Chromosome 8 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How FGL1 connects Entity context

The extracted context around FGL1 shows recurring relationship patterns in the source. For example, FGL1 → body of pancreas, buccal mucosa cell, endometrium, islet of Langerhans, left lobe of liver, left testis, motor neuron, pancreatic epithelial cell, Paneth cell, placenta, primary oocyte, primitive streak, proximal tubule, right kidney, right lobe of liver, secondary oocyte, sexually immature organism, sperm, supraoptic nucleus, testicle Another extracted example is FGL1 → 8p22, 8|8 A4. Use these groups to spot repeated connection types before inspecting the individual relationships.

FGL1

Top relations

Bgee · 20
FGL1 → body of pancreas, buccal mucosa cell, endometrium, islet of Langerhans, left lobe of liver, left testis, motor neuron, pancreatic epithelial cell, Paneth cell, placenta, primary oocyte, primitive streak, proximal tubule, right kidney, right lobe of liver, secondary oocyte, sexually immature organism, sperm, supraoptic nucleus, testicle
RNA expression pattern · 20
FGL1 → body of pancreas, buccal mucosa cell, endometrium, islet of Langerhans, left lobe of liver, left testis, motor neuron, pancreatic epithelial cell, Paneth cell, placenta, primary oocyte, primitive streak, proximal tubule, right kidney, right lobe of liver, secondary oocyte, sexually immature organism, sperm, supraoptic nucleus, testicle
Band · 2
FGL1 → 8p22, 8|8 A4
Chr. · 2
FGL1 → Chromosome 8 (human), Chromosome 8 (mouse)
End · 2
FGL1 → 17,910,365 bp, 41,668,193 bp
Aliases · 1
FGL1 → FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1, fibrinogen like 1, HPS
BioGPS · 1
FGL1 → More reference expression data
Databases · 1
FGL1 → NCBI: entry; OMA: entry
Ensembl · 1
FGL1 → ENSG00000104760
Entrez · 1
FGL1 → 2267

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fgl-1 bp gene chr human band fibrinogen chromosome protein location mouse family fibrinogen-like four 910 365 end 17 668 193

FGL1 relationships Subject–Predicate–Object triples

TTTA extracted 60 structured relationships around FGL1. Examples in this analysis include FGL1 → Aliases → FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1, fibrinogen like 1, HPS and FGL1 → Band → 8p22. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FGL1AliasesFGL1, HFREP1, HP-041, LFIRE-1, LFIRE1, fibrinogen like 1, HPS1.00infobox
FGL1Band8p221.00infobox
FGL1Band8|8 A41.00infobox
FGL1Bgeeright lobe of liver1.00infobox
FGL1Bgeebody of pancreas1.00infobox
FGL1Bgeesperm1.00infobox
FGL1Bgeeislet of Langerhans1.00infobox
FGL1Bgeebuccal mucosa cell1.00infobox
FGL1Bgeetesticle1.00infobox
FGL1Bgeepancreatic epithelial cell1.00infobox
FGL1Bgeeendometrium1.00infobox
FGL1Bgeeplacenta1.00infobox
FGL1Bgeeleft testis1.00infobox
FGL1Bgeeleft lobe of liver1.00infobox
FGL1Bgeesexually immature organism1.00infobox
FGL1Bgeemotor neuron1.00infobox
FGL1Bgeeprimary oocyte1.00infobox
FGL1Bgeeright kidney1.00infobox
FGL1Bgeeproximal tubule1.00infobox
FGL1Bgeesecondary oocyte1.00infobox
FGL1Bgeeprimitive streak1.00infobox
FGL1BgeePaneth cell1.00infobox
FGL1Bgeesupraoptic nucleus1.00infobox
FGL1BioGPSMore reference expression data1.00infobox
FGL1Chr.Chromosome 8 (human)1.00infobox
FGL1Chr.Chromosome 8 (mouse)1.00infobox
FGL1DatabasesNCBI: entry; OMA: entry1.00infobox
FGL1End17,910,365 bp1.00infobox
FGL1End41,668,193 bp1.00infobox
FGL1EnsemblENSG000001047601.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around FGL1 bring nearby vocabulary together. In this analysis, examples include Location, Chromosome and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • fibrinogen
    • Family
    • Fibrinogen-like
    • Members
    • Fgl1
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Clinical
    • Function
  • FGL1
    • Location
    • Chromosome
    • Gene
    • Human
    • Bp
    • Chr
    • Clinical
    • Fibrinogen
    • Function
    • Humans
    • References
    • Significance
  • fgl1
    • Location
    • Chromosome
    • Gene
    • Human
    • Bp
    • Chr
    • Clinical
    • Fibrinogen
    • Function
    • Humans
    • References
    • Significance
  • fibrinogen-like protein 2
    • Also
    • Expressed
    • Protein
    • Related
    • Structurally
    • Fibrinogen
    • End
    • Mouse
    • Cells
    • Family
    • Fgl1
    • Lag-3
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Clinical
    • Exist
    • Function
    • Humans
    • References
    • Significance
    • Splice
  • protein
    • Also
    • Expressed
    • Related
    • Structurally
    • Cells
    • End
    • Lag-3
    • Mouse
    • Family
    • Fgl1
    • Location
    • Band
  • clinical significance
    • Clinical
    • Function
    • References
    • Significance
    • Fgl1
    • Location
    • Chromosome
    • Gene
    • Human
    • Bp
    • Chr
    • Fibrinogen
  • function
    • References
    • Significance
    • Location
    • Chromosome
    • Gene
    • Human
    • Bp
    • Chr

Connections between topic areas Semantic bridges

For FGL1, one of the stronger structural bridges in this analysis connects FGL1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FGL1Function · splits 9 ⟂ 15
FGL1Overview · splits 18 ⟂ 6

Map overview Semantic statistics

FGL1

Nodes24
Edges23
Triples60
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around FGL1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — FGL1 · EN edition · Analysis: TopicsToTalkAbout

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