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CD32

CD32 (cluster of differentiation 32), also known as FcγRII or FCGR2, is a surface receptor glycoprotein belonging to the Ig gene superfamily. CD32 can be found on the surface of a variety of immune cells. CD32 has a low-affinity for the Fc region of IgG antibodies in monomeric form, but high affinity for IgG immune complexes. CD32 has two major…

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Alt. symbols
FCG2, FCGR2A1, FCGR2
Domains
InterPro
HGNC
3616
Locus
Chr. 1 q23
NCBI gene
2212
OMIM
146790

Topics to explore

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Overview

Structure and signaling

Functions and locations

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Map overview Semantic statistics

CD32

Nodes56
Edges55
Triples64
Avg. degree1.96
Density0.035714
Components1

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CD32

Top relations

related to Structure and signaling · 17
CD32 → Additionally, Both, CD32A, CD32B, CD32C, IgG, IgG1, IgG2, IgG3, IgG4, ITAM, ITIM, MAP, SH2, The, When, Whereas
related to CD32B · 14
CD32 → Activated CD32B, BCRs, CD32B, CD32B-deficient, FcR-dependent, FDCs, Having, IgG, Likewise, SLE, Some, The, This, Thus
related to CD32A · 12
CD32 → CD32A, CD4, DC's, DCs, IgG, IgG-opsonized Escherichia, ITAM, Langerhans, On, On DCs, PF4, When
related to CD32C · 6
CD32 → ADCC, Animal, CD32C, It, NK, When
related to External links · 4
CD32 → Antigens, Medicine Medical Subject Headings, MeSH, National Library
Alt. symbols · 1
CD32 → FCG2, FCGR2A1, FCGR2
Domains · 1
CD32 → InterPro
HGNC · 1
CD32 → 3616
Locus · 1
CD32 → Chr. 1 q23
NCBI gene · 1
CD32 → 2212

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Important terminology

cd32b cd32a immune cells cd32c found also cell surface complexes responses igg cellular autoimmunity activation region antibodies associated functions plays

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CD32Alt. symbolsFCG2, FCGR2A1, FCGR21.00infobox
CD32DomainsInterPro1.00infobox
CD32HGNC36161.00infobox
CD32LocusChr. 1 q231.00infobox
CD32NCBI gene22121.00infobox
CD32OMIM1467901.00infobox
CD32RefSeqNM_0216421.00infobox
CD32Search forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CD32StructuresSwiss-model1.00infobox
CD32SymbolFCGR2A1.00infobox
CD32UniProtP123181.00infobox
CD32related to CD32ACD32A0.60section

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